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FR2868313B1 - Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2868313B1
FR2868313B1 FR0403359A FR0403359A FR2868313B1 FR 2868313 B1 FR2868313 B1 FR 2868313B1 FR 0403359 A FR0403359 A FR 0403359A FR 0403359 A FR0403359 A FR 0403359A FR 2868313 B1 FR2868313 B1 FR 2868313B1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
compositions containing
heterocyclic compound
antioxidant agent
novel association
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0403359A
Other languages
English (en)
Other versions
FR2868313A1 (fr
Inventor
Louis Casteilla
Luc Penicaud
Pascal Berthelot
Catherine Dacquet
Daniel Henri Caignard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Laboratoires Servier SAS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0403359A priority Critical patent/FR2868313B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Laboratoires Servier SAS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to CNB2005800108104A priority patent/CN100536842C/zh
Priority to JP2007505592A priority patent/JP2007530643A/ja
Priority to EP05744511A priority patent/EP1729767A1/fr
Priority to US10/593,681 priority patent/US20070167502A1/en
Priority to PCT/FR2005/000755 priority patent/WO2005099694A1/fr
Priority to AU2005232420A priority patent/AU2005232420B8/en
Priority to ZA200607798A priority patent/ZA200607798B/en
Priority to BRPI0509389-9A priority patent/BRPI0509389A/pt
Priority to EA200601632A priority patent/EA012966B1/ru
Priority to UAA200611437A priority patent/UA86801C2/ru
Priority to GEAP20059679A priority patent/GEP20094637B/en
Priority to MYPI20051401A priority patent/MY142039A/en
Priority to CA002563104A priority patent/CA2563104A1/fr
Priority to KR1020067022781A priority patent/KR100842567B1/ko
Priority to ARP050101262A priority patent/AR048355A1/es
Publication of FR2868313A1 publication Critical patent/FR2868313A1/fr
Priority to MA29320A priority patent/MA28467B1/fr
Priority to NO20064858A priority patent/NO20064858L/no
Priority to HK07106254.1A priority patent/HK1099689A1/xx
Application granted granted Critical
Publication of FR2868313B1 publication Critical patent/FR2868313B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0403359A 2004-03-31 2004-03-31 Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent Expired - Fee Related FR2868313B1 (fr)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR0403359A FR2868313B1 (fr) 2004-03-31 2004-03-31 Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
GEAP20059679A GEP20094637B (en) 2004-03-31 2005-03-30 Combination of a heterocyclic compound and an antioxidant and use thereof for treating obesity
EP05744511A EP1729767A1 (fr) 2004-03-31 2005-03-30 Association entre un compose heterocyclique et un agent antioxydant et son utilisation pour le traitement de l'obesite
US10/593,681 US20070167502A1 (en) 2004-03-31 2005-03-30 Association between a heterocyclic compound and an antioxidant agent
PCT/FR2005/000755 WO2005099694A1 (fr) 2004-03-31 2005-03-30 Association entre un compose heterocyclique et un agent antioxydant et son utilisation pour le traitement de l’obesite
AU2005232420A AU2005232420B8 (en) 2004-03-31 2005-03-30 Combination of a heterocyclic compound and an antioxidant and use thereof for treating obesity
ZA200607798A ZA200607798B (en) 2004-03-31 2005-03-30 Combination of a heterocyclic compound and an antioxidant and use thereof for treating obesity
CA002563104A CA2563104A1 (fr) 2004-03-31 2005-03-30 Association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
JP2007505592A JP2007530643A (ja) 2004-03-31 2005-03-30 複素環化合物と抗酸化剤との組合わせ、および肥満症を処置するためのその使用
UAA200611437A UA86801C2 (ru) 2004-03-31 2005-03-30 Комбинация гетероциклического соединения и антиоксидантного вещества и фармацевтическая композиция, которая ее содержит
CNB2005800108104A CN100536842C (zh) 2004-03-31 2005-03-30 杂环化合物和抗氧剂之间的联合形式及其在制备用于治疗肥胖药物的应用
EA200601632A EA012966B1 (ru) 2004-03-31 2005-03-30 Комбинация гетероциклического соединения и антиоксиданта, ее применение и содержащая ее фармацевтическая композиция для лечения или предотвращения ожирения
BRPI0509389-9A BRPI0509389A (pt) 2004-03-31 2005-03-30 associação entre um composto heterocìclico e um agente antioxidante e sua utilização para o tratamento da obesidade
KR1020067022781A KR100842567B1 (ko) 2004-03-31 2005-03-30 헤테로시클릭 화합물과 산화방지제의 회합체 및 이의 비만치료를 위한 용도
MYPI20051401A MY142039A (en) 2004-03-31 2005-03-30 New association between a heterocyclic compound and an antioxidant agent, and pharmaceutical compositions containing them
ARP050101262A AR048355A1 (es) 2004-03-31 2005-03-31 Asociacion entre un compuesto heterociclico y un agente antioxidante y las composiciones farmaceuticas que los contienen
MA29320A MA28467B1 (fr) 2004-03-31 2006-09-14 Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
NO20064858A NO20064858L (no) 2004-03-31 2006-10-25 Nye assosiasjon mellom en heterosyklisk forbindelse og et antioksidantmiddel, og farmasoytiske sammensetninger inneholdende dem
HK07106254.1A HK1099689A1 (en) 2004-03-31 2007-06-12 Combination of a heterocyclic compound and an antioxidant and use thereof for the manufacture of a medicament for treating obesity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0403359A FR2868313B1 (fr) 2004-03-31 2004-03-31 Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2868313A1 FR2868313A1 (fr) 2005-10-07
FR2868313B1 true FR2868313B1 (fr) 2008-08-15

Family

ID=34945535

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0403359A Expired - Fee Related FR2868313B1 (fr) 2004-03-31 2004-03-31 Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent

Country Status (19)

Country Link
US (1) US20070167502A1 (fr)
EP (1) EP1729767A1 (fr)
JP (1) JP2007530643A (fr)
KR (1) KR100842567B1 (fr)
CN (1) CN100536842C (fr)
AR (1) AR048355A1 (fr)
AU (1) AU2005232420B8 (fr)
BR (1) BRPI0509389A (fr)
CA (1) CA2563104A1 (fr)
EA (1) EA012966B1 (fr)
FR (1) FR2868313B1 (fr)
GE (1) GEP20094637B (fr)
HK (1) HK1099689A1 (fr)
MA (1) MA28467B1 (fr)
MY (1) MY142039A (fr)
NO (1) NO20064858L (fr)
UA (1) UA86801C2 (fr)
WO (1) WO2005099694A1 (fr)
ZA (1) ZA200607798B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2894965B1 (fr) * 2005-12-20 2008-01-25 Servier Lab Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2898125B1 (fr) * 2006-03-06 2008-06-13 Servier Lab Nouveaux derives heterocycliques cycloalkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015595A1 (fr) * 1993-01-06 1994-07-21 Jemo-Pharm A/S Preparation comprenant une substance active pharmacologique/biologique
AU748608B2 (en) * 1997-05-01 2002-06-06 Bristol-Myers Squibb Company MTP inhibitors and fat soluble vitamin therapeutic combinations to lower serum lipid levels
US6020383A (en) * 1999-01-11 2000-02-01 Eastman Chemicals Company Method for reducing blood cholesterol and/or blood triglycerides
FR2804431A1 (fr) * 2000-02-02 2001-08-03 Adir Nouveaux derives heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE10044805A1 (de) * 2000-09-11 2002-04-04 Martin Klingenberg Verwendung von Coenzym Q zur Regulierung der Funktion der Entkopplerproteine
CA2426625C (fr) * 2000-10-26 2010-06-01 Fournier Laboratories Ireland Limited Combinaison de fenofibrate et de coenzyme q10 permettant de traiter un dysfonctionnement endothelial
JP2003116487A (ja) * 2001-10-15 2003-04-22 Beverly Corporation:Kk 痩身用食品
FR2845601B1 (fr) * 2002-10-11 2005-07-08 Servier Lab Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
WO2005099694A8 (fr) 2006-11-09
MA28467B1 (fr) 2007-03-01
EA200601632A1 (ru) 2007-04-27
GEP20094637B (en) 2009-03-10
CN100536842C (zh) 2009-09-09
AR048355A1 (es) 2006-04-19
MY142039A (en) 2010-08-30
AU2005232420A1 (en) 2005-10-27
UA86801C2 (ru) 2009-05-25
KR100842567B1 (ko) 2008-07-01
AU2005232420B2 (en) 2009-02-19
EA012966B1 (ru) 2010-02-26
BRPI0509389A (pt) 2007-09-18
HK1099689A1 (en) 2008-10-24
CN1938024A (zh) 2007-03-28
JP2007530643A (ja) 2007-11-01
ZA200607798B (en) 2008-05-28
WO2005099694A1 (fr) 2005-10-27
CA2563104A1 (fr) 2005-10-27
FR2868313A1 (fr) 2005-10-07
NO20064858L (no) 2006-10-25
AU2005232420B8 (en) 2009-06-11
EP1729767A1 (fr) 2006-12-13
US20070167502A1 (en) 2007-07-19
KR20060133073A (ko) 2006-12-22

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20111130