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FR2807434B1 - Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides - Google Patents

Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides

Info

Publication number
FR2807434B1
FR2807434B1 FR0004324A FR0004324A FR2807434B1 FR 2807434 B1 FR2807434 B1 FR 2807434B1 FR 0004324 A FR0004324 A FR 0004324A FR 0004324 A FR0004324 A FR 0004324A FR 2807434 B1 FR2807434 B1 FR 2807434B1
Authority
FR
France
Prior art keywords
tetrahydroisoquinolein
fungicides
derivatives
novel
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0004324A
Other languages
English (en)
Other versions
FR2807434A1 (fr
Inventor
Didier Babin
Yannick Benedetti
Fabienne Chatreaux
John Weston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0004324A priority Critical patent/FR2807434B1/fr
Application filed by Hoechst Marion Roussel, Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel
Priority to CA002405126A priority patent/CA2405126A1/fr
Priority to IL15207201A priority patent/IL152072A0/xx
Priority to MXPA02009764A priority patent/MXPA02009764A/es
Priority to PCT/FR2001/001004 priority patent/WO2001074808A1/fr
Priority to EP01921468A priority patent/EP1272485A1/fr
Priority to US10/240,014 priority patent/US20030187267A1/en
Priority to JP2001572498A priority patent/JP2003529599A/ja
Priority to AU2001248456A priority patent/AU2001248456A1/en
Publication of FR2807434A1 publication Critical patent/FR2807434A1/fr
Application granted granted Critical
Publication of FR2807434B1 publication Critical patent/FR2807434B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FR0004324A 2000-04-05 2000-04-05 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides Expired - Fee Related FR2807434B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR0004324A FR2807434B1 (fr) 2000-04-05 2000-04-05 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides
IL15207201A IL152072A0 (en) 2000-04-05 2001-04-04 New derivatives of 1,2,3,4-tetrahydroisoquinoline, their preparation process and their use as fungicides
MXPA02009764A MXPA02009764A (es) 2000-04-05 2001-04-04 Nuevos derivados de 1,2,3,4-tetrahidroisoquinoleina, su procedimiento de preparacion y su aplicacion como fungicidas.
PCT/FR2001/001004 WO2001074808A1 (fr) 2000-04-05 2001-04-04 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides
CA002405126A CA2405126A1 (fr) 2000-04-05 2001-04-04 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides
EP01921468A EP1272485A1 (fr) 2000-04-05 2001-04-04 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides
US10/240,014 US20030187267A1 (en) 2000-04-05 2001-04-04 Novel 1,2,3,4-tetrahydroisoquinoline, their preparation method and their use as fungicides
JP2001572498A JP2003529599A (ja) 2000-04-05 2001-04-04 １，２，３，４−テトラヒドロイソキノリンの新誘導体、それらの製造方法及びそれらの殺真菌剤としての使用
AU2001248456A AU2001248456A1 (en) 2000-04-05 2001-04-04 Novel 1,2,3,4-tetrahydrosioquinoline, their preparation method and their use as fungicides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0004324A FR2807434B1 (fr) 2000-04-05 2000-04-05 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides

Publications (2)

Publication Number Publication Date
FR2807434A1 FR2807434A1 (fr) 2001-10-12
FR2807434B1 true FR2807434B1 (fr) 2002-10-18

Family

ID=8848876

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0004324A Expired - Fee Related FR2807434B1 (fr) 2000-04-05 2000-04-05 Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides

Country Status (9)

Country Link
US (1) US20030187267A1 (fr)
EP (1) EP1272485A1 (fr)
JP (1) JP2003529599A (fr)
AU (1) AU2001248456A1 (fr)
CA (1) CA2405126A1 (fr)
FR (1) FR2807434B1 (fr)
IL (1) IL152072A0 (fr)
MX (1) MXPA02009764A (fr)
WO (1) WO2001074808A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824325B1 (fr) * 2001-05-04 2003-08-15 Aventis Pharma Sa Nouveaux derives d'azole ou de triazole, leur procede de preparation et leur application comme fongicides
FR2824324B1 (fr) 2001-05-04 2003-08-15 Aventis Pharma Sa Nouveaux derives d'azole ou de triazole, leur procede de preparation et leur application comme medicaments anti-fongiques
ITMI20032020A1 (it) * 2003-10-17 2005-04-18 Italfarmaco Spa Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici
AR080375A1 (es) 2010-03-05 2012-04-04 Sanofi Aventis Procedimiento para la preparacion de 2-(cicloheximetil)-n-{2-[(2s)-1-metilpirrolidin-2-il] etil}-1,2,3,4-tetrahidroisoquinolina- 7-sulfonamida
EP2571871B1 (fr) * 2010-05-19 2017-06-21 Sandoz AG Procédé de préparation de triazolones chiraux
CA2828909C (fr) * 2011-03-04 2019-03-19 Dafra Pharma Research&Development Bvba Oleyl-phosphocholine pour le traitement des mycoses
BR112014028991A2 (pt) 2012-05-22 2017-06-27 Autifony Therapeutics Ltd triazóis como inibidores de kv3

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2813872A (en) * 1957-11-19 New sympatholytic allyl amine com-
DE3039087A1 (de) * 1980-10-16 1982-05-19 Hoechst Ag, 6000 Frankfurt 1-(1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung und ihre verwendung
DE3484023D1 (de) * 1983-03-03 1991-03-07 Basf Ag Azolylmethylcycloalkane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3308554A1 (de) * 1983-03-10 1984-09-13 Hoechst Ag, 6230 Frankfurt 1-/1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung und ihre verwendung
GB8412480D0 (en) * 1984-05-16 1984-06-20 Elliott M Pesticides
US5258544A (en) * 1991-03-05 1993-11-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Synthesis of aldehydes useful in the preparations of HMG-CoA reductase inhibitors
US6140340A (en) * 1998-10-06 2000-10-31 Hoechst Marion Roussel Derivatives of 2-[3-phenyl-2-propenyl]-1,2,3,4-tetrahydro isoquinoline, their process and their use as fungicides

Also Published As

Publication number Publication date
MXPA02009764A (es) 2003-03-27
WO2001074808A1 (fr) 2001-10-11
AU2001248456A1 (en) 2001-10-15
CA2405126A1 (fr) 2001-10-11
EP1272485A1 (fr) 2003-01-08
US20030187267A1 (en) 2003-10-02
JP2003529599A (ja) 2003-10-07
FR2807434A1 (fr) 2001-10-12
IL152072A0 (en) 2003-05-29

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Legal Events

Date Code Title Description
ST Notification of lapse