FR2796073B1 - ANTI-IDIOTYPIC ANTIBODIES FOR FIBROBLAST GROWTH FACTORS AND THEIR USE AS MEDICAMENTS - Google Patents
ANTI-IDIOTYPIC ANTIBODIES FOR FIBROBLAST GROWTH FACTORS AND THEIR USE AS MEDICAMENTSInfo
- Publication number
- FR2796073B1 FR2796073B1 FR9908779A FR9908779A FR2796073B1 FR 2796073 B1 FR2796073 B1 FR 2796073B1 FR 9908779 A FR9908779 A FR 9908779A FR 9908779 A FR9908779 A FR 9908779A FR 2796073 B1 FR2796073 B1 FR 2796073B1
- Authority
- FR
- France
- Prior art keywords
- medicaments
- growth factors
- fibroblast growth
- idiotypic antibodies
- idiotypic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000018233 Fibroblast Growth Factor Human genes 0.000 title 1
- 108050007372 Fibroblast Growth Factor Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6873—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an immunoglobulin; the antibody being an anti-idiotypic antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Botany (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9908779A FR2796073B1 (en) | 1999-07-07 | 1999-07-07 | ANTI-IDIOTYPIC ANTIBODIES FOR FIBROBLAST GROWTH FACTORS AND THEIR USE AS MEDICAMENTS |
EP00949660A EP1189947A1 (en) | 1999-07-07 | 2000-07-06 | Anti-idiotypic antibodies of fibroblast growth factors and their use as medicines |
AU62947/00A AU6294700A (en) | 1999-07-07 | 2000-07-06 | Anti-idiotypic antibodies of fibroblast growth factors and their use as medicines |
JP2001509769A JP2003504379A (en) | 1999-07-07 | 2000-07-06 | Anti-idiotypic antibodies of fibroblast growth factor and their use as drugs |
PCT/FR2000/001952 WO2001004160A1 (en) | 1999-07-07 | 2000-07-06 | Anti-idiotypic antibodies of fibroblast growth factors and their use as medicines |
CA002378451A CA2378451A1 (en) | 1999-07-07 | 2000-07-06 | Anti-idiotypic antibodies of fibroblast growth factors and their use as medicines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9908779A FR2796073B1 (en) | 1999-07-07 | 1999-07-07 | ANTI-IDIOTYPIC ANTIBODIES FOR FIBROBLAST GROWTH FACTORS AND THEIR USE AS MEDICAMENTS |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2796073A1 FR2796073A1 (en) | 2001-01-12 |
FR2796073B1 true FR2796073B1 (en) | 2003-08-29 |
Family
ID=9547809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9908779A Expired - Fee Related FR2796073B1 (en) | 1999-07-07 | 1999-07-07 | ANTI-IDIOTYPIC ANTIBODIES FOR FIBROBLAST GROWTH FACTORS AND THEIR USE AS MEDICAMENTS |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1189947A1 (en) |
JP (1) | JP2003504379A (en) |
AU (1) | AU6294700A (en) |
CA (1) | CA2378451A1 (en) |
FR (1) | FR2796073B1 (en) |
WO (1) | WO2001004160A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100531796C (en) * | 2002-01-31 | 2009-08-26 | 马普科技促进协会 | FGFR agonists |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1332761A1 (en) * | 2002-01-31 | 2003-08-06 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Agonists of fibroblast growth factor receptors (FGFR) |
CN1662254A (en) * | 2002-05-03 | 2005-08-31 | 雷文生物技术公司 | ALCAM and ALCAM modulators |
WO2004022095A1 (en) * | 2002-09-04 | 2004-03-18 | Abtech | Anti-idiotypic antibodies as vegf or fgf agonists for bone therapy |
FR2845691B1 (en) * | 2002-10-10 | 2004-12-10 | Centre Nat Rech Scient | NOVEL ENDOTHELIAL CELLS, ANTIBODIES DIRECTED AGAINST THESE CELLS AND THEIR USE, IN PARTICULAR FOR SCREENING ANGIOGENESIS-INHIBITING SUBSTANCES |
FR2858326A1 (en) * | 2003-08-01 | 2005-02-04 | Abtech | METHOD FOR PREPARING MIMETIC ANTIBODIES OF A SUBSTANCE AND ANTIBODIES THUS OBTAINED |
US7872016B2 (en) | 2004-05-25 | 2011-01-18 | Yale University | Method for treating skeletal disorders resulting from FGFR malfunction |
CA2834879C (en) * | 2011-05-16 | 2019-10-22 | Genentech, Inc. | Fgfr1 agonists and methods of use |
TWI728373B (en) | 2013-12-23 | 2021-05-21 | 美商建南德克公司 | Antibodies and methods of use |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2742662B1 (en) * | 1995-12-21 | 1998-01-23 | Centre Nat Rech Scient | ANTI-IDIOTYPIC ANTIBODIES OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND THEIR USE AS MEDICAMENTS |
US6214795B1 (en) * | 1996-11-12 | 2001-04-10 | Praecis Pharmaceuticals, Inc. | Peptide compounds useful for modulating FGF receptor activity |
CA2310252A1 (en) * | 1998-03-06 | 1999-09-10 | Imclone Systems Incorporated | Active immunization against angiogenesis-associated antigens |
-
1999
- 1999-07-07 FR FR9908779A patent/FR2796073B1/en not_active Expired - Fee Related
-
2000
- 2000-07-06 EP EP00949660A patent/EP1189947A1/en not_active Withdrawn
- 2000-07-06 WO PCT/FR2000/001952 patent/WO2001004160A1/en not_active Application Discontinuation
- 2000-07-06 AU AU62947/00A patent/AU6294700A/en not_active Abandoned
- 2000-07-06 JP JP2001509769A patent/JP2003504379A/en not_active Withdrawn
- 2000-07-06 CA CA002378451A patent/CA2378451A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100531796C (en) * | 2002-01-31 | 2009-08-26 | 马普科技促进协会 | FGFR agonists |
Also Published As
Publication number | Publication date |
---|---|
JP2003504379A (en) | 2003-02-04 |
WO2001004160A1 (en) | 2001-01-18 |
EP1189947A1 (en) | 2002-03-27 |
CA2378451A1 (en) | 2001-01-18 |
AU6294700A (en) | 2001-01-30 |
FR2796073A1 (en) | 2001-01-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |