FR2778105A1 - PLANT EXTRACTS USED TO COMBAT HAIR LOSS AND THEIR PREPARATION - Google Patents

Abstract

The invention concerns extracts obtained by decoction and steam distillation of a combination of plants comprising essentially: 35 to 80 % of myrtle (leaves and fruits); 20 to 65 % of Phyllantus emblica (fruit) or a combination of 2 to 15 % of aniseed, 2 to 15 % zyzyphus (leaves and fruits) and 6 to 25 % of myrobalan, the percentages being expressed in weight with respect to the resulting mixture weight, and optionally plants whereof the extracts have astringent and nutrient properties. The invention also concerns the method for preparing said extracts and their use.

Description

PLANT EXTRACTS USED TO FIGHT AGAINST

  HAIR LOSS AND THEIR PREPARATION

  The invention relates to plant extracts used for combating hair loss, a process for preparing them, and their use for combating hair loss and promoting their regrowth. The problem of hair loss has long held the attention of researchers and many products, either natural or synthetic, have been proposed and try to solve the problem of

  lo more or less satisfactory.

  In addition, certain treatments, notably based on natural products, impose application times of several hours which oblige the user to keep them overnight, with the disadvantages

  because of their fatty character, their smell, etc ...

  The invention overcomes these drawbacks by providing aqueous or oily compositions, requiring shorter application times and giving advantageous results. There is, in fact, a halt in hair loss in two to three

  weeks and a clear regrowth in three months.

  These compositions are obtained from a specific combination of plants which is treated by decoction and distillation by entrainment in water vapor and provides an aqueous composition of plant extracts which can be used as it is or transformed into an oily composition. with vegetable oil or a mixture

vegetable oils.

  The association or mixture of plants contains, as essential constituents, - 35 to 80% myrtle (leaves and fruits) - 20 to 65% of Phyllantus emblica (fruit) or a mixture of green anise, zyzyphus (leaves and fruits) and myrobalam in proportions such as green anise, zyzyphus and myrobalam represent 2 to 15%, 2 to 15% and 6 to 25% respectively

total plant mix.

  Lower proportions of plants with an astringent or nourishing character can be used, and in particular for their astringent role, up to 10% of Rosa gallica or from 1 to 5% of cloves (nails and bark), and for their nourishing role up to 10% potentilla or up to 15% acorn (crushed). These percentages

  are expressed relative to the total weight of the base association.

  In a variant, at most half of the myrtle can be replaced by cypress (leaves and fruits). The above percentages are percentages by weight expressed in relation to fresh myrtle and cypress and in relation to others

dry plants.

  When using a mixture of green anise, zyzyphus and myrobalam, the percentages are chosen so that the total mixture

contains at least 20%.

  Before being used, some plants need to be crushed. The zyzyphus and the cloves will be ground, for example in a rotary grinder, until a powder with an average particle size of 0.5 mm is obtained while the cypress (leaves and fruits) will be ground, for example manually pestle and mortar, until a coarse paste is obtained. The absence of grinding apparently does not allow the extraction of the plant elements constituting

  some of the active ingredients of the hair compositions of the invention.

  Once the mixture of plants has been prepared, twice its weight of water is added to it, it is heated to boiling so as to evaporate substantially half of the water in about five hours at atmospheric pressure and a composition is collected. aqueous extracts of

  plants entrained by water vapor.

  Other procedures or conditions for decoction and distillation by entrainment in steam are among the

  general knowledge of a person skilled in the art.

  After cooling, the aqueous composition can be used

  directly as a processing composition.

  It can also be transformed into an oily composition

according to the following treatment.

  The aqueous composition is added to about once its weight of vegetable oils, preferably chosen from olive oil, sesame oil and bay oil or their mixtures. It is possible in particular to use sesame oil containing from 10 to 50% of olive oil or a mixture of at least 30% of sesame oil and olive oil and

  bay oil in varying proportions.

  The whole is brought to 100 ° C. under moderate conditions and with stirring to remove the water in about three hours. Avoid heating above 100 C to avoid damaging the active ingredients in the composition. Moderate conditions are necessary so as not to entrain the active ingredients with the evaporating water. The operation of extracting the active ingredients with a vegetable oil can also be carried out at temperatures below C or at ambient temperature with laboratory extractors. The oily composition thus obtained is ready for use after cooling. The above aqueous and oily compositions constitute oily lotions and preparations which can be used as such but they can be used to prepare shampoos,

  emulsions or be liposomal, microencapsulated, etc.

  The cosmetic treatment consists in massaging the clean and dry scalp with, at each application, 2 to 5 g of an oily or aqueous composition. Brushing is recommended

  hyperemic beforehand to prepare the scalp for treatment.

  After massage, leave on for at least one to two hours. This minimum duration, however, allows the treatment to be applied in the evening and shampoo before bedtime. In the case where an aqueous composition is used, the shampoo is not even necessary because

  the composition dries quickly, is not greasy and allows styling.

  The application is daily at the start of treatment then will be spaced up to twice a week and will continue for as long

as necessary.

  After four to five weeks, there is a considerable slowdown in the fall and a slight regrowth. Significant regrowth was seen after five / six months in subjects with old alopecia, some even having a factor

aggravating genetics.

  The preparation of the aqueous and oily compositions of

  the invention will be described in more detail in the examples below.

Example 1

  Preparation of an aqueous extract Weigh: - 62.5 g of myrtle (leaves and fruit) - 37.5 g of cypress (leaves and fruit) - 25 g of green anise, g of zyzyphus - 50 g of myrobalam - 10 g of cloves (nails and bark) The zyzyphus and the cloves were previously ground in a rotary mill to obtain a powder with a particle size of 0.5 mm, while the cypress is crushed with a pestle and

  mortar until a coarse paste is formed.

  The plants are introduced into a flask equipped with a thermometer and a refrigerant. Double their weight, 420 g of water, is added and the mixture is heated under moderate conditions to evaporate half of the water in about 5 hours. The residual contents of the flask are discarded and 220 ml of an aqueous extract containing water are collected and

  the compounds distilled by steam entrainment.

  After cooling, the extract obtained can be used directly as an aqueous composition for treating hair loss or else transformed into an oily composition as described.

below.

Example 2

  Preparation of an oily composition.

  200 g of olive oil and 800 g of sesame oil are added to 1 liter of an aqueous extract obtained according to the procedure of Example 1 and the mixture is heated to 100 ° C. under moderate conditions for

evaporate the water in three hours.

Example 3

  Aqueous extracts are then prepared, then oily compositions using the vegetable products and the oils indicated in the following table in the proportions (in% by weight) also indicated in

table.

  Example A B C D E F Myrtle 35 45 53 49 40 69

Cypress 25 25 20 7 26 -

Phyllantus 40 - 27 44 - 31

Zyzyphus - 10 - - 10 -

Anise - 10 10-

Myrobalam - 10 - 14 -

Clove - 5 - - 5 -

  Olive oil 25 40 42 50 40 15 Sesame 75 50 40 50 60 30 Laurel - 10 18 - 55 Each of the aqueous and oily compositions obtained in Examples 1, 2 and 3A to 3F is used to treat the scalp of patients suffering from old or recent alopecia. In each case, a clean and dry scalp is brushed beforehand, which makes it possible to prepare it for the application of

the treatment composition.

  Apply 3 g each time (the dose can range from 2 to 5 g) of the composition and massage the scalp 2 to 3 minutes before leaving

ask two hours.

  The application is done, for practical reasons, in the evening and

  oily compositions are removed before bedtime by shampoo.

  The aqueous compositions can also be removed by shampoo but this is not essential because they dry quickly and do not

not grease the scalp.

  After four to five weeks, there is a fall arrest and slight regrowth. We can then space the application which, on a daily basis, will gradually become two to three times per

week.

  Treatment for three months causes significant hair regrowth, which demonstrates the effectiveness of the previous hair compositions.

Claims (10)

  1. Extracts obtained by decoction and distillation by steam entrainment of a combination of plants which essentially comprises: 35 to 80% myrtle (leaves and fruits) - 20 to 65% of Phyllantus emblica (fruit) or d 'a combination of 2 to 15% of green anise, 2 to 15% of zyzyphus (leaves and fruits) and 6 to% of myrobalam, the percentages being expressed by weight relative to the weight of the lo mixture thus obtained, as well as possibly plants whose   extracts have an astringent or nourishing character.   2. Extracts according to claim 1, for which obtaining at most half of the myrtle contained in the combination of plants has been   replaced by cypress (leaves and fruit).   3. Extracts according to claim 1 or 2, for which one uses up to 10% of Rosa gallica and / or 1 to 5% of cloves (nails and bark), as a plant with astringent character, and / or up to 10% of cinquefoil and / or up to 15% of acorn of crushed oak, as a nourishing agent, the percentages being expressed by weight   compared to the combination of basic plants.   4. Extracts according to any one of claims 1 to 3, set   in oily form by extraction of the initial aqueous extract with a vegetable oil.   5. Extracts according to claim 4, obtained by using olive oil, sesame oil or bay oil or a mixture thereof. 6. Method for preparing extracts according to one of   Claims 1 to 3, characterized in that the association of   plants twice its weight of water, it is heated to a boil under moderate conditions by substantially distilling half of the water at atmospheric pressure in five hours, and collecting an extract   aqueous containing active ingredients entrained by water vapor.   7. Process for the preparation of extracts according to one or other of the   Claims 4 and 5, characterized in that the aqueous extract is added   obtained by the method of claim 6 at about once its weight of vegetable oil and heated to 100 C under moderate conditions and with stirring for about two hours to evaporate the water. 8. Process for the preparation of extracts according to one or other of the   Claims 6 and 7, characterized in that, before mixing the plants,   we grind the zyzyphus and the possible clove, in a grinder   rotary, with a particle size of about 0.5 mm.   9. Process for the preparation of extracts according to any one of   Claims 6 to 8, characterized in that the cypress (leaves and fruits),   possibly used and crushed manually with pestle and mortar   until a coarse paste is obtained.   10. Use of extracts according to any one of   claims 1 to 5 or obtained by the process according to any one   of claims 6 to 9, for a cosmetic treatment of the scalp   in order to fight against hair loss and to promote their regrowth.