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FR2768817B1 - HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL - Google Patents

HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL

Info

Publication number
FR2768817B1
FR2768817B1 FR9711721A FR9711721A FR2768817B1 FR 2768817 B1 FR2768817 B1 FR 2768817B1 FR 9711721 A FR9711721 A FR 9711721A FR 9711721 A FR9711721 A FR 9711721A FR 2768817 B1 FR2768817 B1 FR 2768817B1
Authority
FR
France
Prior art keywords
biological material
determination
detection
phosphorylating activity
homogeneous method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9711721A
Other languages
French (fr)
Other versions
FR2768817A1 (en
Inventor
Gerard Mathis
Eric Trinquet
Marc Preaudat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9711721A priority Critical patent/FR2768817B1/en
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Priority to PCT/FR1998/001976 priority patent/WO1999015896A1/en
Priority to DE69813850T priority patent/DE69813850T2/en
Priority to ES98943995T priority patent/ES2198744T3/en
Priority to US09/486,701 priority patent/US6753156B1/en
Priority to JP2000513143A priority patent/JP4312953B2/en
Priority to EP98943995A priority patent/EP1018009B1/en
Priority to AT98943995T priority patent/ATE238551T1/en
Publication of FR2768817A1 publication Critical patent/FR2768817A1/en
Application granted granted Critical
Publication of FR2768817B1 publication Critical patent/FR2768817B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to a novel homogeneous method of detecting and/or determining the phosphorylating activity of a biological material towards a substrate containing tyrosine and/or serine and/or threonine, and to a kit for carrying out this method.
FR9711721A 1997-09-19 1997-09-19 HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL Expired - Fee Related FR2768817B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9711721A FR2768817B1 (en) 1997-09-19 1997-09-19 HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL
DE69813850T DE69813850T2 (en) 1997-09-19 1998-09-16 HOMOGENEOUS DETECTION METHOD FOR DETERMINING THE PHOSPHORYLATION ACTIVITIES OF BIOLOGICAL MATERIAL
ES98943995T ES2198744T3 (en) 1997-09-19 1998-09-16 HOMOGENEO METHOD FOR THE DETECTION AND / OR DETERMINATION OF THE PHOSPHORILING ACTIVITY OF A BIOLOGICAL MATERIAL.
US09/486,701 US6753156B1 (en) 1997-09-19 1998-09-16 Homogeneous method for detecting and/or determining phosphorylating activity in a biological material
PCT/FR1998/001976 WO1999015896A1 (en) 1997-09-19 1998-09-16 Homogeneous method for detecting and/or determining phosphorylating activity in a biological material
JP2000513143A JP4312953B2 (en) 1997-09-19 1998-09-16 Homogeneous method for detecting and / or measuring the phosphorylation activity of a biological substance and kit used to perform the method
EP98943995A EP1018009B1 (en) 1997-09-19 1998-09-16 Homogeneous method for detecting and/or determining phosphorylating activity in a biological material
AT98943995T ATE238551T1 (en) 1997-09-19 1998-09-16 HOMOGENEOUS DETECTION METHODS FOR DETERMINING THE PHOSPHORYLATION ACTIVITIES OF BIOLOGICAL MATERIAL

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9711721A FR2768817B1 (en) 1997-09-19 1997-09-19 HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL

Publications (2)

Publication Number Publication Date
FR2768817A1 FR2768817A1 (en) 1999-03-26
FR2768817B1 true FR2768817B1 (en) 1999-12-10

Family

ID=9511294

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9711721A Expired - Fee Related FR2768817B1 (en) 1997-09-19 1997-09-19 HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL

Country Status (8)

Country Link
US (1) US6753156B1 (en)
EP (1) EP1018009B1 (en)
JP (1) JP4312953B2 (en)
AT (1) ATE238551T1 (en)
DE (1) DE69813850T2 (en)
ES (1) ES2198744T3 (en)
FR (1) FR2768817B1 (en)
WO (1) WO1999015896A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6938493B2 (en) 1997-07-21 2005-09-06 Helix Technology Corporation Apparatus and methods for heat loss pressure measurement
WO2001007638A2 (en) * 1999-07-27 2001-02-01 University Of Utah Research Foundation Homogeneous fluorescence method for assaying structural modifications of biomolecules
CN1222767C (en) * 2000-02-28 2005-10-12 第一化学药品株式会社 Measuring method using long life fluorescence of excitation type
JP4206378B2 (en) * 2002-07-08 2009-01-07 哲雄 長野 Fluorescent probe
US20060211122A1 (en) * 2002-10-16 2006-09-21 Tetsuo Nagano Reagents for the measurement of peroxynitrites
US7696245B2 (en) * 2003-03-28 2010-04-13 Sekisui Medical Co., Ltd. Fluorescent probe for zinc
DE10321901A1 (en) * 2003-05-06 2004-12-02 Proteosys Ag Affinity enrichment of phosphorylated peptides and / or proteins
JP2005194244A (en) * 2004-01-09 2005-07-21 Shigenobu Yano Zinc ion fluorescence sensor
DE102004022628A1 (en) * 2004-05-07 2005-12-15 Sensient Imaging Technologies Gmbh FRET bioassay
WO2005113563A1 (en) * 2004-05-19 2005-12-01 Merck Patent Gmbh Metal complexes
DE102004034517A1 (en) * 2004-07-16 2006-02-16 Covion Organic Semiconductors Gmbh metal complexes
FR2899689B1 (en) * 2006-04-10 2016-05-20 Cis Bio Int METHOD OF SUPPRESSING A FRET SIGNAL, FREQUENCY SIGNALING AGENTS AND USE IN A BIOLOGICAL MULTIPLEXING METHOD
US7605009B2 (en) * 2007-03-12 2009-10-20 Silverbrook Research Pty Ltd Method of fabrication MEMS integrated circuits
DE102011001368B4 (en) 2011-03-17 2013-01-31 Bundesanstalt für Materialforschung und -Prüfung (BAM) Lanthanoid chelates containing particles, their preparation and their use in bioanalysis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570703B1 (en) * 1984-09-26 1988-07-08 Commissariat Energie Atomique RARE EARTH MACROPOLYCYCLIC COMPLEXES AND APPLICATION AS FLUORESCENT MARKERS
US5279943A (en) * 1985-08-02 1994-01-18 Compagnie Oris Industrie Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present
FR2585836B1 (en) * 1985-08-02 1987-11-27 Commissariat Energie Atomique HOMOGENEOUS METHOD FOR LUMINESCENCE DETECTION AND / OR DETERMINATION OF AN ANALYTE IN A MEDIUM CONTAINING IT
WO1992000388A1 (en) * 1990-07-02 1992-01-09 The Regents Of The University Of California Detection of analytes using fluorescent energy transfer
FR2680787B1 (en) * 1991-08-30 1994-11-04 Cis Bio Int MACROCYCLIC RARE EARTH COMPLEXES AND THEIR USE FOR REDUCING INTERFERENCE IN FLUORESCENCE ASSAY.
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
FR2735238B1 (en) * 1995-06-09 1997-09-05 Cis Bio Int USE OF A BINDING PHYCOBILIPROTEIN-PEPTIDE COMPLEX AS A FLUORESCENT TRACER
EP0915989B1 (en) * 1996-07-16 2010-06-02 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
US5925558A (en) * 1996-07-16 1999-07-20 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
US5759787A (en) * 1996-08-26 1998-06-02 Tularik Inc. Kinase assay
US6203994B1 (en) * 1997-12-05 2001-03-20 Pharmacia & Upjohn Company Fluorescence-based high throughput sereening assays for protein kinases and phosphatases

Also Published As

Publication number Publication date
ATE238551T1 (en) 2003-05-15
DE69813850T2 (en) 2004-04-01
FR2768817A1 (en) 1999-03-26
EP1018009A1 (en) 2000-07-12
JP4312953B2 (en) 2009-08-12
EP1018009B1 (en) 2003-04-23
DE69813850D1 (en) 2003-05-28
JP2001517796A (en) 2001-10-09
US6753156B1 (en) 2004-06-22
WO1999015896A1 (en) 1999-04-01
ES2198744T3 (en) 2004-02-01

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Legal Events

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