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FR2759584B1 - PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF HETEROCYCLIC COMPOUNDS IN QUATERNARY AMMONIUM FORM - Google Patents

PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF HETEROCYCLIC COMPOUNDS IN QUATERNARY AMMONIUM FORM

Info

Publication number
FR2759584B1
FR2759584B1 FR9701825A FR9701825A FR2759584B1 FR 2759584 B1 FR2759584 B1 FR 2759584B1 FR 9701825 A FR9701825 A FR 9701825A FR 9701825 A FR9701825 A FR 9701825A FR 2759584 B1 FR2759584 B1 FR 2759584B1
Authority
FR
France
Prior art keywords
pharmaceutical composition
quaternary ammonium
oral administration
heterocyclic compounds
ammonium form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9701825A
Other languages
French (fr)
Other versions
FR2759584A1 (en
Inventor
Jean-Claude Gautier
Xavier Boulenc
Regine Bellamy
Bernard Abramovici
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR9701825A priority Critical patent/FR2759584B1/en
Priority to HR9701825A priority patent/HRP980075A2/en
Priority to ARP980100675A priority patent/AR011805A1/en
Priority to AU64049/98A priority patent/AU6404998A/en
Priority to JP53543298A priority patent/JP2001511795A/en
Priority to EP98909549A priority patent/EP0969825A1/en
Priority to ZA981289A priority patent/ZA981289B/en
Priority to CA002281560A priority patent/CA2281560A1/en
Priority to BR9807694A priority patent/BR9807694A/en
Priority to PCT/FR1998/000298 priority patent/WO1998035662A1/en
Publication of FR2759584A1 publication Critical patent/FR2759584A1/en
Application granted granted Critical
Publication of FR2759584B1 publication Critical patent/FR2759584B1/en
Priority to NO993928A priority patent/NO993928D0/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FR9701825A 1997-02-17 1997-02-17 PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF HETEROCYCLIC COMPOUNDS IN QUATERNARY AMMONIUM FORM Expired - Fee Related FR2759584B1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR9701825A FR2759584B1 (en) 1997-02-17 1997-02-17 PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF HETEROCYCLIC COMPOUNDS IN QUATERNARY AMMONIUM FORM
ARP980100675A AR011805A1 (en) 1997-02-17 1998-02-16 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION OF AN ACTIVE SUBSTANCE.
HR9701825A HRP980075A2 (en) 1997-02-17 1998-02-16 Pharmaceutical composition for oral administration of heterocyclic compounds in the form of quaternary ammonium
JP53543298A JP2001511795A (en) 1997-02-17 1998-02-17 Pharmaceutical compositions for oral administration of heterocyclic compounds in the form of quaternary ammonium
EP98909549A EP0969825A1 (en) 1997-02-17 1998-02-17 Pharmaceutical composition for oral administration of heterocyclic compounds in the form of quaternary ammonium
ZA981289A ZA981289B (en) 1997-02-17 1998-02-17 Pharmaceutical composition for the oral administration of heterocyclic compounds in quaternary ammonium form
AU64049/98A AU6404998A (en) 1997-02-17 1998-02-17 Pharmaceutical composition for oral administration of heterocyclic compounds in the form of quaternary ammonium
CA002281560A CA2281560A1 (en) 1997-02-17 1998-02-17 Pharmaceutical composition for oral administration of heterocyclic compounds in the form of quaternary ammonium
BR9807694A BR9807694A (en) 1997-02-17 1998-02-17 of an active principle
PCT/FR1998/000298 WO1998035662A1 (en) 1997-02-17 1998-02-17 Pharmaceutical composition for oral administration of heterocyclic compounds in the form of quaternary ammonium
NO993928A NO993928D0 (en) 1997-02-17 1999-08-16 Pharmaceutical composition for oral administration of heterocyclic compounds in the form of quaternary ammonium

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9701825A FR2759584B1 (en) 1997-02-17 1997-02-17 PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF HETEROCYCLIC COMPOUNDS IN QUATERNARY AMMONIUM FORM

Publications (2)

Publication Number Publication Date
FR2759584A1 FR2759584A1 (en) 1998-08-21
FR2759584B1 true FR2759584B1 (en) 1999-06-11

Family

ID=9503804

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9701825A Expired - Fee Related FR2759584B1 (en) 1997-02-17 1997-02-17 PHARMACEUTICAL COMPOSITION FOR THE ORAL ADMINISTRATION OF HETEROCYCLIC COMPOUNDS IN QUATERNARY AMMONIUM FORM

Country Status (11)

Country Link
EP (1) EP0969825A1 (en)
JP (1) JP2001511795A (en)
AR (1) AR011805A1 (en)
AU (1) AU6404998A (en)
BR (1) BR9807694A (en)
CA (1) CA2281560A1 (en)
FR (1) FR2759584B1 (en)
HR (1) HRP980075A2 (en)
NO (1) NO993928D0 (en)
WO (1) WO1998035662A1 (en)
ZA (1) ZA981289B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102188424B (en) * 2011-03-23 2013-03-27 浙江理工大学 Anti-leukemia effects of SR140333

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676054B1 (en) * 1991-05-03 1993-09-03 Sanofi Elf NOVEL N-ALKYLENEPIPERIDINO COMPOUNDS AND THEIR ENANTIOMERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2676055B1 (en) * 1991-05-03 1993-09-03 Sanofi Elf AMINO POLYCYCLIC COMPOUNDS AND THEIR ENANTIOMERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2688219B1 (en) * 1992-03-03 1994-07-08 Sanofi Elf AMATONIUM QUATERNARY SALTS OF AMINO AROMATIC COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2696178B1 (en) * 1992-09-30 1994-12-30 Sanofi Elf Quaternary basic amides, process for their preparation and pharmaceutical compositions containing them.
FR2717804B1 (en) * 1994-03-25 1996-06-21 Sanofi Sa Salts of substituted nitrogen heteroaromatic compounds, process for their preparation and pharmaceutical compositions containing them.
DE69508093T2 (en) * 1994-08-25 1999-07-15 Merrell Pharmaceuticals Inc., Cincinnati, Ohio SUBSTITUTED PIPERIDINE FOR THE TREATMENT OF ALLERGIC DISEASES
FR2725900B1 (en) * 1994-10-21 1997-07-18 Sanofi Sa USE OF NK1 RECEPTOR ANTAGONISTS FOR THE PREPARATION OF DRUGS WITH CARDIOREGULATORY ACTION
FR2725986B1 (en) * 1994-10-21 1996-11-29 Adir NOVEL PIPERIDINE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2729954B1 (en) * 1995-01-30 1997-08-01 Sanofi Sa SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2729951B1 (en) * 1995-01-30 1997-04-18 Sanofi Sa NOVEL HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

Also Published As

Publication number Publication date
EP0969825A1 (en) 2000-01-12
NO993928L (en) 1999-08-16
CA2281560A1 (en) 1998-08-20
AU6404998A (en) 1998-09-08
AR011805A1 (en) 2000-09-13
ZA981289B (en) 1998-08-26
BR9807694A (en) 2000-03-21
FR2759584A1 (en) 1998-08-21
HRP980075A2 (en) 1998-10-31
JP2001511795A (en) 2001-08-14
NO993928D0 (en) 1999-08-16
WO1998035662A1 (en) 1998-08-20

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Legal Events

Date Code Title Description
ST Notification of lapse