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FR2758884B1 - METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM - Google Patents

METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM

Info

Publication number
FR2758884B1
FR2758884B1 FR9701313A FR9701313A FR2758884B1 FR 2758884 B1 FR2758884 B1 FR 2758884B1 FR 9701313 A FR9701313 A FR 9701313A FR 9701313 A FR9701313 A FR 9701313A FR 2758884 B1 FR2758884 B1 FR 2758884B1
Authority
FR
France
Prior art keywords
analyte
reagent
medium
quantifying
isolating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9701313A
Other languages
French (fr)
Other versions
FR2758884A1 (en
Inventor
Agnes Perrin
Alain Theretz
Bernard Mandrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9701313A priority Critical patent/FR2758884B1/en
Application filed by Biomerieux SA filed Critical Biomerieux SA
Priority to AU61045/98A priority patent/AU6104598A/en
Priority to DE69803443T priority patent/DE69803443T2/en
Priority to US09/355,246 priority patent/US6342396B1/en
Priority to EP98905473A priority patent/EP0965045B1/en
Priority to CA002280187A priority patent/CA2280187A1/en
Priority to AT98905473T priority patent/ATE211824T1/en
Priority to PCT/FR1998/000182 priority patent/WO1998034116A1/en
Priority to JP53259598A priority patent/JP4053092B2/en
Publication of FR2758884A1 publication Critical patent/FR2758884A1/en
Application granted granted Critical
Publication of FR2758884B1 publication Critical patent/FR2758884B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method for at least one of detecting, quantifying or isolating at least one analyte from a liquid medium in which the analyte is distributed and comprises providing a reagent comprised of particles having a receptor for an analyte fixed to the particles distributed in the medium and a capturing means having an exposed surface defining an active zone. An intermediate reagent is formed by the complex of the reagent with the analyte. A second receptor is fixed in the active zone to capture either the analyte bound by the reagent or the receptor (capture partners). The active zone serves as a site of isolation and concentration of the capture partners.
FR9701313A 1997-01-30 1997-01-30 METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM Expired - Fee Related FR2758884B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR9701313A FR2758884B1 (en) 1997-01-30 1997-01-30 METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM
DE69803443T DE69803443T2 (en) 1997-01-30 1998-01-30 METHOD FOR ISOLATING, DETECTING OR QUANTIFYING AN ANALYTIC IN A MEDIUM
US09/355,246 US6342396B1 (en) 1997-01-30 1998-01-30 Method for isolating, in particular for detecting or quantifying an analyte in a medium
EP98905473A EP0965045B1 (en) 1997-01-30 1998-01-30 Method for isolating, in particular for detecting or quantifying an analyte in a medium
AU61045/98A AU6104598A (en) 1997-01-30 1998-01-30 Method for isolating, in particular for detecting or quantifying an analyte in amedium
CA002280187A CA2280187A1 (en) 1997-01-30 1998-01-30 Method for isolating, in particular for detecting or quantifying an analyte in a medium
AT98905473T ATE211824T1 (en) 1997-01-30 1998-01-30 METHOD FOR ISOLATION, DETECTION OR QUANTIFICATION OF AN ANALYTE IN A MEDIUM
PCT/FR1998/000182 WO1998034116A1 (en) 1997-01-30 1998-01-30 Method for isolating, in particular for detecting or quantifying an analyte in a medium
JP53259598A JP4053092B2 (en) 1997-01-30 1998-01-30 Method for isolating, in particular detecting or quantifying an analyte in a medium

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9701313A FR2758884B1 (en) 1997-01-30 1997-01-30 METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM

Publications (2)

Publication Number Publication Date
FR2758884A1 FR2758884A1 (en) 1998-07-31
FR2758884B1 true FR2758884B1 (en) 1999-04-02

Family

ID=9503365

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9701313A Expired - Fee Related FR2758884B1 (en) 1997-01-30 1997-01-30 METHOD FOR ISOLATING, IN PARTICULAR DETECTING OR QUANTIFYING AN ANALYTE IN A MEDIUM

Country Status (9)

Country Link
US (1) US6342396B1 (en)
EP (1) EP0965045B1 (en)
JP (1) JP4053092B2 (en)
AT (1) ATE211824T1 (en)
AU (1) AU6104598A (en)
CA (1) CA2280187A1 (en)
DE (1) DE69803443T2 (en)
FR (1) FR2758884B1 (en)
WO (1) WO1998034116A1 (en)

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Also Published As

Publication number Publication date
JP4053092B2 (en) 2008-02-27
FR2758884A1 (en) 1998-07-31
JP2001510565A (en) 2001-07-31
CA2280187A1 (en) 1998-08-06
DE69803443D1 (en) 2002-02-28
US6342396B1 (en) 2002-01-29
WO1998034116A1 (en) 1998-08-06
ATE211824T1 (en) 2002-01-15
EP0965045A1 (en) 1999-12-22
EP0965045B1 (en) 2002-01-09
AU6104598A (en) 1998-08-25
DE69803443T2 (en) 2002-09-05

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