FR2719048B1 - Bases nucléiques polycationiques et oligonucléotides les contenant. - Google Patents

Bases nucléiques polycationiques et oligonucléotides les contenant.

Info

Publication number: FR2719048B1
Authority: FR; France
Prior art keywords: oligonucleotides containing; nucleic bases; polycationic nucleic; polycationic; bases
Prior art date: 1994-04-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

FR9405133A

Other languages

English (en)

Other versions

FR2719048A1 (fr

Inventor

Jean-Paul Behr

Nathalie Schmid

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Centre National de la Recherche Scientifique CNRS

Universite de Strasbourg

Original Assignee

Centre National de la Recherche Scientifique CNRS

Universite de Strasbourg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-25

Filing date

1994-04-25

Publication date

1996-07-19

1994-04-25 Application filed by Centre National de la Recherche Scientifique CNRS, Universite de Strasbourg filed Critical Centre National de la Recherche Scientifique CNRS

1994-04-25 Priority to FR9405133A priority Critical patent/FR2719048B1/fr

1995-04-25 Priority to PCT/FR1995/000542 priority patent/WO1995029184A1/fr

1995-10-27 Publication of FR2719048A1 publication Critical patent/FR2719048A1/fr

1996-07-19 Application granted granted Critical

1996-07-19 Publication of FR2719048B1 publication Critical patent/FR2719048B1/fr

2014-04-25 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

108091034117 Oligonucleotide Proteins 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Saccharide Compounds (AREA)

FR9405133A 1994-04-25 1994-04-25 Bases nucléiques polycationiques et oligonucléotides les contenant. Expired - Fee Related FR2719048B1 (fr)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
FR9405133A FR2719048B1 (fr)	1994-04-25	1994-04-25	Bases nucléiques polycationiques et oligonucléotides les contenant.
PCT/FR1995/000542 WO1995029184A1 (fr)	1994-04-25	1995-04-25	Bases nucleiques polycationiques et oligonucleotides les contenant

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9405133A FR2719048B1 (fr)	1994-04-25	1994-04-25	Bases nucléiques polycationiques et oligonucléotides les contenant.

Publications (2)

Publication Number	Publication Date
FR2719048A1 FR2719048A1 (fr)	1995-10-27
FR2719048B1 true FR2719048B1 (fr)	1996-07-19

Family

ID=9462602

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR9405133A Expired - Fee Related FR2719048B1 (fr)	1994-04-25	1994-04-25	Bases nucléiques polycationiques et oligonucléotides les contenant.

Country Status (2)

Country	Link
FR (1)	FR2719048B1 (fr)
WO (1)	WO1995029184A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6312894B1 (en)	1995-04-03	2001-11-06	Epoch Pharmaceuticals, Inc.	Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
US5801155A (en) *	1995-04-03	1998-09-01	Epoch Pharmaceuticals, Inc.	Covalently linked oligonucleotide minor grove binder conjugates
US6770740B1 (en)	1999-07-13	2004-08-03	The Regents Of The University Of Michigan	Crosslinked DNA condensate compositions and gene delivery methods
US7205105B2 (en)	1999-12-08	2007-04-17	Epoch Biosciences, Inc.	Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis
US7348146B2 (en)	2003-10-02	2008-03-25	Epoch Biosciences, Inc.	Single nucleotide polymorphism analysis of highly polymorphic target sequences
DK1687609T3 (en)	2003-10-28	2015-01-12	Epoch Biosciences Inc	Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background

1994
- 1994-04-25 FR FR9405133A patent/FR2719048B1/fr not_active Expired - Fee Related
1995
- 1995-04-25 WO PCT/FR1995/000542 patent/WO1995029184A1/fr active Application Filing

Also Published As

Publication number	Publication date
WO1995029184A1 (fr)	1995-11-02
FR2719048A1 (fr)	1995-10-27

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Legal Events

Date	Code	Title	Description
2006-01-27	ST	Notification of lapse	Effective date: 20051230