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FR2712493B1 - Use of photosensitizers derived from the phorbine nucleus for the decontamination of blood infected by parasites and / or viruses. - Google Patents

Use of photosensitizers derived from the phorbine nucleus for the decontamination of blood infected by parasites and / or viruses.

Info

Publication number
FR2712493B1
FR2712493B1 FR9313666A FR9313666A FR2712493B1 FR 2712493 B1 FR2712493 B1 FR 2712493B1 FR 9313666 A FR9313666 A FR 9313666A FR 9313666 A FR9313666 A FR 9313666A FR 2712493 B1 FR2712493 B1 FR 2712493B1
Authority
FR
France
Prior art keywords
phorbine
decontamination
parasites
viruses
nucleus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9313666A
Other languages
French (fr)
Other versions
FR2712493A1 (en
Inventor
Schrevel Joseph
Grellier Philippe
Santus Rene
Maziere Jean-Claude
Gatt Shimon
Dagan Arie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9313666A priority Critical patent/FR2712493B1/en
Priority to PCT/FR1994/001317 priority patent/WO1995013809A1/en
Publication of FR2712493A1 publication Critical patent/FR2712493A1/en
Application granted granted Critical
Publication of FR2712493B1 publication Critical patent/FR2712493B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Use of phorbine ring derived photosensitizer compounds for the decontamination of parasite and/or virus-infected blood products. The invention also concerns a method for the production of drugs for the extracorporeal treatment of parasite or viral pathologies.
FR9313666A 1993-11-16 1993-11-16 Use of photosensitizers derived from the phorbine nucleus for the decontamination of blood infected by parasites and / or viruses. Expired - Fee Related FR2712493B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9313666A FR2712493B1 (en) 1993-11-16 1993-11-16 Use of photosensitizers derived from the phorbine nucleus for the decontamination of blood infected by parasites and / or viruses.
PCT/FR1994/001317 WO1995013809A1 (en) 1993-11-16 1994-11-10 Use of phorbine ring derived photosensitizer compounds for the decontamination of parasite and/or virus-infected blood

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9313666A FR2712493B1 (en) 1993-11-16 1993-11-16 Use of photosensitizers derived from the phorbine nucleus for the decontamination of blood infected by parasites and / or viruses.

Publications (2)

Publication Number Publication Date
FR2712493A1 FR2712493A1 (en) 1995-05-24
FR2712493B1 true FR2712493B1 (en) 1996-01-19

Family

ID=9452900

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9313666A Expired - Fee Related FR2712493B1 (en) 1993-11-16 1993-11-16 Use of photosensitizers derived from the phorbine nucleus for the decontamination of blood infected by parasites and / or viruses.

Country Status (2)

Country Link
FR (1) FR2712493B1 (en)
WO (1) WO1995013809A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5492924A (en) * 1993-09-24 1996-02-20 Fox Chase Cancer Center Phorbine derivatives and their use in the diagnosis and therapy of cancer
CA2474448C (en) * 2002-02-01 2010-09-07 Gambro, Inc. Inactivation of west nile virus and malaria using photosensitizers
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61275228A (en) * 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド Photodynamic inactivity of virus in therapeutical protein composition
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
JPH0786109B2 (en) * 1987-12-21 1995-09-20 浜理薬品工業株式会社 Pheophorbide derivative
AU648631B2 (en) * 1990-12-20 1994-04-28 Baxter International Inc. Systems and methods for simultaneously removing free and entrained contaminants in fluids like blood using photoactive therapy and cellular separation techniques
US5288605A (en) * 1992-03-02 1994-02-22 Steritech, Inc. Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen

Also Published As

Publication number Publication date
FR2712493A1 (en) 1995-05-24
WO1995013809A1 (en) 1995-05-26

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Legal Events

Date Code Title Description
ST Notification of lapse