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FR2669631B1 - Nouveaux derives de l'oxazolidine, leur preparation et leur emploi. - Google Patents

Nouveaux derives de l'oxazolidine, leur preparation et leur emploi.

Info

Publication number
FR2669631B1
FR2669631B1 FR909014635A FR9014635A FR2669631B1 FR 2669631 B1 FR2669631 B1 FR 2669631B1 FR 909014635 A FR909014635 A FR 909014635A FR 9014635 A FR9014635 A FR 9014635A FR 2669631 B1 FR2669631 B1 FR 2669631B1
Authority
FR
France
Prior art keywords
preparation
oxazolidine derivatives
new
new oxazolidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR909014635A
Other languages
English (en)
Other versions
FR2669631A1 (fr
Inventor
Alain Commercon
Jean-Marc Paris
Commercon Alain
Paris Jean-Marc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR909014635A priority Critical patent/FR2669631B1/fr
Priority to MX9102128A priority patent/MX9102128A/es
Priority to ZA919224A priority patent/ZA919224B/xx
Priority to YU182691A priority patent/YU48150B/sh
Priority to AT92900928T priority patent/ATE111905T1/de
Priority to NZ247867A priority patent/NZ247867A/en
Priority to ES92900928T priority patent/ES2059207T3/es
Priority to DE69104223T priority patent/DE69104223T2/de
Priority to CZ1993965A priority patent/CZ286749B6/cs
Priority to DE69128971T priority patent/DE69128971T2/de
Priority to DK92900928.0T priority patent/DK0558623T3/da
Priority to DK93119434.4T priority patent/DK0595370T3/da
Priority to AT93119434T priority patent/ATE163415T1/de
Priority to AU90838/91A priority patent/AU655618B2/en
Priority to US08/050,495 priority patent/US5476954A/en
Priority to IE407391A priority patent/IE65642B1/en
Priority to CA002096833A priority patent/CA2096833C/fr
Priority to PT99580A priority patent/PT99580B/pt
Priority to NZ240698A priority patent/NZ240698A/en
Priority to IE950417A priority patent/IE80681B1/en
Priority to JP4502105A priority patent/JP3043411B2/ja
Priority to PL91299189A priority patent/PL166893B1/pl
Priority to RU9193043106A priority patent/RU2095356C1/ru
Priority to PCT/FR1991/000928 priority patent/WO1992009589A1/fr
Priority to EP93119434A priority patent/EP0595370B1/fr
Priority to EP92900928A priority patent/EP0558623B1/fr
Priority to ES93119434T priority patent/ES2112377T3/es
Priority to KR1019930701547A priority patent/KR100206457B1/ko
Priority to SK507-93A priority patent/SK282162B6/sk
Priority to HU9301500A priority patent/HU214332B/hu
Publication of FR2669631A1 publication Critical patent/FR2669631A1/fr
Priority to NO931805A priority patent/NO302699B1/no
Priority to FI932331A priority patent/FI105184B/fi
Application granted granted Critical
Publication of FR2669631B1 publication Critical patent/FR2669631B1/fr
Priority to GR970402588T priority patent/GR3026238T3/el
Priority to FI981590A priority patent/FI106261B/fi
Priority to PT102283A priority patent/PT102283B/pt
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR909014635A 1990-11-23 1990-11-23 Nouveaux derives de l'oxazolidine, leur preparation et leur emploi. Expired - Lifetime FR2669631B1 (fr)

Priority Applications (35)

Application Number Priority Date Filing Date Title
FR909014635A FR2669631B1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de l'oxazolidine, leur preparation et leur emploi.
MX9102128A MX9102128A (es) 1990-11-23 1991-11-19 Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
YU182691A YU48150B (sh) 1990-11-23 1991-11-21 Postupak za dobivanje derivata taksana i dobiveni novi derivati
ZA919224A ZA919224B (en) 1990-11-23 1991-11-21 Process for preparing taxane derivatives,new derivatives obtained and pharmaceutical compositions containing them
PL91299189A PL166893B1 (pl) 1990-11-23 1991-11-22 Sposób wytwarzania pochodnych taksanu PL PL
ES92900928T ES2059207T3 (es) 1990-11-23 1991-11-22 Procedimiento para la preparacion de derivados del taxano, nuevos derivados obtenidos y composiciones farmaceuticas que les contienen.
DE69104223T DE69104223T2 (de) 1990-11-23 1991-11-22 Verfahren zur herstellung von taxanderivaten, so erhaltene neue derivate und pharmazeutische zusammensetzungen, die sie enthalten.
CZ1993965A CZ286749B6 (cs) 1990-11-23 1991-11-22 Způsob přípravy derivátů taxanu, nové takto získané deriváty a farmaceutické kompozice tyto deriváty obsahující
DE69128971T DE69128971T2 (de) 1990-11-23 1991-11-22 Verfahren zur Herstellung von Taxanderivaten und deren Zwischenprodukte
DK92900928.0T DK0558623T3 (da) 1990-11-23 1991-11-22 Fremgangsmåde til fremstilling af taxanderivater, herved fremstillede nye derivater og farmaceutiske præparater indeholdende disse derivater
DK93119434.4T DK0595370T3 (da) 1990-11-23 1991-11-22 Fremgangsmåde til fremstilling af taxanderivater og derved anvendte mellemprodukter
AT93119434T ATE163415T1 (de) 1990-11-23 1991-11-22 Verfahren zur herstellung von taxanderivaten und deren zwischenprodukte
AU90838/91A AU655618B2 (en) 1990-11-23 1991-11-22 Method for preparing taxane derivatives, novel derivatives thereby obtained and pharmaceutical compositions containing same
US08/050,495 US5476954A (en) 1990-11-23 1991-11-22 Process for preparing taxane derivatives, new derivatives obtained and pharmaceutical compositions containing them
IE407391A IE65642B1 (en) 1990-11-23 1991-11-22 Process for preparing taxane derivatives new derivatives obtained and pharmaceutical compositions containing them
CA002096833A CA2096833C (fr) 1990-11-23 1991-11-22 Procede de preparation de derives de taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent
PT99580A PT99580B (pt) 1990-11-23 1991-11-22 Processo de preparacao de derivados do taxol ou de 10-desacetiltaxol, dos seus intermediarios e de composicoes farmaceuticas que os contem
NZ240698A NZ240698A (en) 1990-11-23 1991-11-22 Process for preparing taxanes using oxazolidine derivatives, taxane derivatives and pharmaceutical compositions
AT92900928T ATE111905T1 (de) 1990-11-23 1991-11-22 Verfahren zur herstellung von taxanderivaten, so erhaltene neue derivate und pharmazeutische zusammensetzungen, die sie enthalten.
JP4502105A JP3043411B2 (ja) 1990-11-23 1991-11-22 タクサン誘導体の製造法、製造される新規な誘導体、及びこれを含む製薬学的組成物
NZ247867A NZ247867A (en) 1990-11-23 1991-11-22 Oxazolidine derivatives and their preparation
RU9193043106A RU2095356C1 (ru) 1990-11-23 1991-11-22 Способ получения производных таксана и производные таксана
PCT/FR1991/000928 WO1992009589A1 (fr) 1990-11-23 1991-11-22 Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent
EP93119434A EP0595370B1 (fr) 1990-11-23 1991-11-22 Procédé de préparation de dérivés du taxane et intermédiaires
EP92900928A EP0558623B1 (fr) 1990-11-23 1991-11-22 Procede de preparation de derives du taxane, nouveaux derives obtenus et compositions pharmaceutiques qui les contiennent
ES93119434T ES2112377T3 (es) 1990-11-23 1991-11-22 Procedimiento para la preparacion de derivados del taxano y productos intermedios.
KR1019930701547A KR100206457B1 (ko) 1990-11-23 1991-11-22 탁산 유도체의 제조 방법, 이로써 얻어진 신규한 유도체 및 이를 함유하는 제약학적 조성물
SK507-93A SK282162B6 (sk) 1990-11-23 1991-11-22 Spôsob prípravy derivátov taxánu, deriváty taxánu, deriváty oxazolínu ako medziprodukty na prípravu derivátov taxánu a spôsob ich prípravy
HU9301500A HU214332B (hu) 1990-11-23 1991-11-22 Eljárás taxánszármazékok és az új származékokat tartalmazó gyógyszerkészítmények előállítására
IE950417A IE80681B1 (en) 1990-11-23 1991-11-22 Process for preparing taxane derivatives new derivatives obtained and pharmaceutical compositions containing them
NO931805A NO302699B1 (no) 1990-11-23 1993-05-18 Fremstilling av taxanderivater samt mellomprodukter til bruk ved fremstillingen
FI932331A FI105184B (fi) 1990-11-23 1993-05-21 Menetelmä taksaanijohdannaisten valmistamiseksi ja välituotteet
GR970402588T GR3026238T3 (en) 1990-11-23 1998-02-26 Method for preparing taxane derivatives, novel derivatives thereby obtained and pharmaceutical compositions containing same.
FI981590A FI106261B (fi) 1990-11-23 1998-07-10 Menetelmä uusien terapeuttisesti käyttökelpoisten taksaanijohdannaisten valmistamiseksi
PT102283A PT102283B (pt) 1990-11-23 1999-04-07 Processo de preparacao de derivados de taxol ou de 10-desacetiltaxol e intermediarios

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909014635A FR2669631B1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de l'oxazolidine, leur preparation et leur emploi.

Publications (2)

Publication Number Publication Date
FR2669631A1 FR2669631A1 (fr) 1992-05-29
FR2669631B1 true FR2669631B1 (fr) 1994-09-09

Family

ID=9402517

Family Applications (1)

Application Number Title Priority Date Filing Date
FR909014635A Expired - Lifetime FR2669631B1 (fr) 1990-11-23 1990-11-23 Nouveaux derives de l'oxazolidine, leur preparation et leur emploi.

Country Status (2)

Country Link
FR (1) FR2669631B1 (fr)
ZA (1) ZA919224B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5728725A (en) * 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
CA2170661A1 (fr) 1995-03-22 1996-09-23 John K. Thottathil Methodes pour la preparation de taxanes a l'aide d'oxazolidines comme produits intermediaires
JP2000510470A (ja) 1996-05-06 2000-08-15 フロリダ・ステイト・ユニバーシティ １―デオキシバッカチンｉｉｉ、１―デオキシタキソールおよび１―デオキシタキソール類似体、ならびにこれらの製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
ZA919224B (en) 1992-08-26
FR2669631A1 (fr) 1992-05-29

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