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FR2581456B1 - Villine humaine, en tant que marqueur de cellules malignes primaires originaires du tube digestif, et moyens, en particulier anticorps diriges contre la villine humaine, pour la detection desdites cellules malignes - Google Patents

Villine humaine, en tant que marqueur de cellules malignes primaires originaires du tube digestif, et moyens, en particulier anticorps diriges contre la villine humaine, pour la detection desdites cellules malignes

Info

Publication number
FR2581456B1
FR2581456B1 FR8506707A FR8506707A FR2581456B1 FR 2581456 B1 FR2581456 B1 FR 2581456B1 FR 8506707 A FR8506707 A FR 8506707A FR 8506707 A FR8506707 A FR 8506707A FR 2581456 B1 FR2581456 B1 FR 2581456B1
Authority
FR
France
Prior art keywords
villine
malignant cells
human
marker
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8506707A
Other languages
English (en)
Other versions
FR2581456A1 (fr
Inventor
Daniel Louvard
Brigitte Dudouet
Sylvie Robine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8506707A priority Critical patent/FR2581456B1/fr
Application filed by Institut Pasteur filed Critical Institut Pasteur
Priority to EP92105747A priority patent/EP0502553B1/fr
Priority to PCT/FR1986/000150 priority patent/WO1986006494A1/fr
Priority to EP86400957A priority patent/EP0206849B1/fr
Priority to JP61502415A priority patent/JP2688481B2/ja
Priority to DE86400957T priority patent/DE3689084T2/de
Priority to AT92105747T priority patent/ATE156136T1/de
Priority to DE3650641T priority patent/DE3650641T2/de
Priority to AT86400957T priority patent/ATE95313T1/de
Publication of FR2581456A1 publication Critical patent/FR2581456A1/fr
Application granted granted Critical
Publication of FR2581456B1 publication Critical patent/FR2581456B1/fr
Priority to US07/662,992 priority patent/US5188967A/en
Priority to JP6290159A priority patent/JP2698326B2/ja
Priority to US08/422,613 priority patent/US5635389A/en
Priority to JP7290113A priority patent/JP2698337B2/ja
Priority to JP9145137A priority patent/JPH1066574A/ja
Priority to JP10225587A priority patent/JPH11123091A/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4735—Villin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR8506707A 1985-05-02 1985-05-02 Villine humaine, en tant que marqueur de cellules malignes primaires originaires du tube digestif, et moyens, en particulier anticorps diriges contre la villine humaine, pour la detection desdites cellules malignes Expired FR2581456B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR8506707A FR2581456B1 (fr) 1985-05-02 1985-05-02 Villine humaine, en tant que marqueur de cellules malignes primaires originaires du tube digestif, et moyens, en particulier anticorps diriges contre la villine humaine, pour la detection desdites cellules malignes
AT86400957T ATE95313T1 (de) 1985-05-02 1986-04-30 Verfahren zur in vitro-diagnose von boesartigen zellen aus dem verdauungstrakt.
PCT/FR1986/000150 WO1986006494A1 (fr) 1985-05-02 1986-04-30 Moyens pour le diagnostic in vitro de cellules malignesorigi naires du tube digestif
EP86400957A EP0206849B1 (fr) 1985-05-02 1986-04-30 Moyens pour le diagnostic in vitro de cellules malignes originaires du tube digestif
JP61502415A JP2688481B2 (ja) 1985-05-02 1986-04-30 消化管起源の悪性細胞のｉｎ ｖｉｔｒｏ検出方法
DE86400957T DE3689084T2 (de) 1985-05-02 1986-04-30 Verfahren zur in vitro-Diagnose von bösartigen Zellen aus dem Verdauungstrakt.
AT92105747T ATE156136T1 (de) 1985-05-02 1986-04-30 Peptidfragment des menschlichen villins und antikörper dagegen
DE3650641T DE3650641T2 (de) 1985-05-02 1986-04-30 Peptidfragment des menschlichen Villins und Antikörper dagegen
EP92105747A EP0502553B1 (fr) 1985-05-02 1986-04-30 Fragment peptidique de la villine humaine et anticorps la reconnaissant
US07/662,992 US5188967A (en) 1985-05-02 1991-02-28 Agents for the in vitro diagnosis of malignant cells originating in the digestive tract
JP6290159A JP2698326B2 (ja) 1985-05-02 1994-11-24 消化管起源の悪性細胞のｉｎ ｖｉｔｒｏ検出に使用し得る絨毛タンパク質をコードするＤＮＡの合成法
US08/422,613 US5635389A (en) 1985-05-02 1995-04-13 Antibodies which recognize and bind human villin
JP7290113A JP2698337B2 (ja) 1985-05-02 1995-11-08 消化管起源の悪性細胞のｉｎ ｖｉｔｒｏ検出に使用し得る抗絨毛モノクローナル抗体
JP9145137A JPH1066574A (ja) 1985-05-02 1997-06-03 消化管起源の悪性細胞のｉｎ ｖｉｔｒｏ検出に使用し得る抗絨毛タンパク質をコードするＤＮＡ
JP10225587A JPH11123091A (ja) 1985-05-02 1998-08-10 消化管起源の悪性細胞のｉｎ ｖｉｔｒｏ検出に使用し得るヒト絨毛タンパク質

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8506707A FR2581456B1 (fr) 1985-05-02 1985-05-02 Villine humaine, en tant que marqueur de cellules malignes primaires originaires du tube digestif, et moyens, en particulier anticorps diriges contre la villine humaine, pour la detection desdites cellules malignes

Publications (2)

Publication Number Publication Date
FR2581456A1 FR2581456A1 (fr) 1986-11-07
FR2581456B1 true FR2581456B1 (fr) 1987-07-17

Family

ID=9318907

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8506707A Expired FR2581456B1 (fr) 1985-05-02 1985-05-02 Villine humaine, en tant que marqueur de cellules malignes primaires originaires du tube digestif, et moyens, en particulier anticorps diriges contre la villine humaine, pour la detection desdites cellules malignes

Country Status (2)

Country Link
JP (1) JP2688481B2 (fr)
FR (1) FR2581456B1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2919060B1 (fr) 2007-07-19 2012-11-30 Biomerieux Sa Procede de dosage de l'ezrine pour le diagnostic in vitro du cancer colorectal.
JP5715817B2 (ja) 2007-07-19 2015-05-13 ビオメリューＢｉｏｍｅｒｉｅｕｘ 結腸直腸癌のインビトロ診断のための肝臓脂肪酸結合タンパク質、ｃｅａおよびｃａ１９−９のアッセイのための方法
FR2919064B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine all pour le diagnostic in vitro du cancer colorectal
FR2919063B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
FR2919065B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal
FR2919062B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'aminoacylase 1 pour le diagnostic in vitro du cancer colorectal.
FR2933773B1 (fr) 2008-07-10 2013-02-15 Biomerieux Sa Procede de dosage de la proteine disulfide isomerase pour le diagnostic in vitro du cancer colorectal

Also Published As

Publication number Publication date
JPS62502687A (ja) 1987-10-15
FR2581456A1 (fr) 1986-11-07
JP2688481B2 (ja) 1997-12-10

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Legal Events

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TP Transmission of property
ST Notification of lapse