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FR2539412B1 - 5-FLUORURACIL DERIVATIVES AND THEIR THERAPEUTIC USES AS CARCINOSTATIC AGENTS - Google Patents

5-FLUORURACIL DERIVATIVES AND THEIR THERAPEUTIC USES AS CARCINOSTATIC AGENTS

Info

Publication number
FR2539412B1
FR2539412B1 FR8300457A FR8300457A FR2539412B1 FR 2539412 B1 FR2539412 B1 FR 2539412B1 FR 8300457 A FR8300457 A FR 8300457A FR 8300457 A FR8300457 A FR 8300457A FR 2539412 B1 FR2539412 B1 FR 2539412B1
Authority
FR
France
Prior art keywords
fluoruracil
derivatives
therapeutic uses
carcinostatic agents
carcinostatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8300457A
Other languages
French (fr)
Other versions
FR2539412A1 (en
Inventor
Shoichiro Ozaki
Tomonori Hoshiko
Tomio Ogasawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR8300457A priority Critical patent/FR2539412B1/en
Publication of FR2539412A1 publication Critical patent/FR2539412A1/en
Application granted granted Critical
Publication of FR2539412B1 publication Critical patent/FR2539412B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8300457A 1983-01-13 1983-01-13 5-FLUORURACIL DERIVATIVES AND THEIR THERAPEUTIC USES AS CARCINOSTATIC AGENTS Expired FR2539412B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8300457A FR2539412B1 (en) 1983-01-13 1983-01-13 5-FLUORURACIL DERIVATIVES AND THEIR THERAPEUTIC USES AS CARCINOSTATIC AGENTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8300457A FR2539412B1 (en) 1983-01-13 1983-01-13 5-FLUORURACIL DERIVATIVES AND THEIR THERAPEUTIC USES AS CARCINOSTATIC AGENTS

Publications (2)

Publication Number Publication Date
FR2539412A1 FR2539412A1 (en) 1984-07-20
FR2539412B1 true FR2539412B1 (en) 1986-02-21

Family

ID=9284900

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8300457A Expired FR2539412B1 (en) 1983-01-13 1983-01-13 5-FLUORURACIL DERIVATIVES AND THEIR THERAPEUTIC USES AS CARCINOSTATIC AGENTS

Country Status (1)

Country Link
FR (1) FR2539412B1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240352B1 (en) * 1986-04-02 1992-12-16 Chisso Corporation 5-fluorouracil derivatives and processes for producing thereof
PL170961B1 (en) * 1991-08-14 1997-02-28 Procter & Gamble Pharma Method of obtaining novelurea derivatives useful as agents against arrythmia and fibrillation
EP1092432A1 (en) * 1999-10-15 2001-04-18 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Anti-ischemic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324951B2 (en) * 1973-11-28 1978-07-24
JPS607622B2 (en) * 1976-04-26 1985-02-26 三井東圧化学株式会社 1-Production method of carbamoyl-uracils
JPS5946509B2 (en) * 1976-11-04 1984-11-13 三井東圧化学株式会社 1-Substituted cyclohexylcarbamoyl-5-fluorouracils and their production method
JPS6011705B2 (en) * 1976-11-05 1985-03-27 小野薬品工業株式会社 5-Fluorouracil derivative compound
EP0010941B1 (en) * 1978-10-30 1982-05-12 Fujisawa Pharmaceutical Co., Ltd. 5-fluorouracil derivatives, preparation thereof and their pharmaceutical compositions
JPS5569569A (en) * 1978-11-21 1980-05-26 Mitsui Toatsu Chem Inc Carcinostatic
JPS55136267A (en) * 1979-04-08 1980-10-23 Tokyo Kinzoku Kogyo Kk Pyrimidine derivative

Also Published As

Publication number Publication date
FR2539412A1 (en) 1984-07-20

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Legal Events

Date Code Title Description
ST Notification of lapse