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FR2445833A1 - Nouveaux sels d'antibiotiques amines a cycle beta lactame - Google Patents

Nouveaux sels d'antibiotiques amines a cycle beta lactame

Info

Publication number
FR2445833A1
FR2445833A1 FR7900148A FR7900148A FR2445833A1 FR 2445833 A1 FR2445833 A1 FR 2445833A1 FR 7900148 A FR7900148 A FR 7900148A FR 7900148 A FR7900148 A FR 7900148A FR 2445833 A1 FR2445833 A1 FR 2445833A1
Authority
FR
France
Prior art keywords
water soluble
carbonate
soluble salts
antibiotics
lactam ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7900148A
Other languages
English (en)
Other versions
FR2445833B1 (fr
Inventor
Jean Blum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chimie and Biologie
Original Assignee
Chimie and Biologie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimie and Biologie filed Critical Chimie and Biologie
Priority to FR7900148A priority Critical patent/FR2445833A1/fr
Publication of FR2445833A1 publication Critical patent/FR2445833A1/fr
Application granted granted Critical
Publication of FR2445833B1 publication Critical patent/FR2445833B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

La présente invention a pour objet de nouveaux sels d'antibiotiques aminés à cycle beta lactame caractérisés en ce qu'ils sont préparés en milieu anhydre par réaction entre l'antibiotique libre et un carbonate ou bicarbonate métallique pharmaceutiquement acceptable. La présente invention a également pour objet le procédé de fabrication de ces nouveaux sels et leur utilisation comme médicaments pour les thérapeutiques humaine et vétérinaire.
FR7900148A 1979-01-04 1979-01-04 Nouveaux sels d'antibiotiques amines a cycle beta lactame Granted FR2445833A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7900148A FR2445833A1 (fr) 1979-01-04 1979-01-04 Nouveaux sels d'antibiotiques amines a cycle beta lactame

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7900148A FR2445833A1 (fr) 1979-01-04 1979-01-04 Nouveaux sels d'antibiotiques amines a cycle beta lactame

Publications (2)

Publication Number Publication Date
FR2445833A1 true FR2445833A1 (fr) 1980-08-01
FR2445833B1 FR2445833B1 (fr) 1982-02-12

Family

ID=9220462

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7900148A Granted FR2445833A1 (fr) 1979-01-04 1979-01-04 Nouveaux sels d'antibiotiques amines a cycle beta lactame

Country Status (1)

Country Link
FR (1) FR2445833A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2532849A1 (fr) * 1982-09-10 1984-03-16 Glaxo Group Ltd Composition pharmaceutique solide contenant des antibiotiques b-lactamiques, son procede de preparation et procede pour stabiliser une composition pharmaceutique
EP0303223A3 (en) * 1987-08-10 1990-11-28 Fujisawa Pharmaceutical Co., Ltd. Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
WO2006072577A1 (fr) * 2005-01-07 2006-07-13 Sandoz Ag Procede de preparation de granules comprenant de l’amoxicilline

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2124499A1 (fr) * 1971-02-05 1972-09-22 Squibb & Sons Inc
US3969524A (en) * 1974-08-13 1976-07-13 Hoffmann-La Roche Inc. Stable amoxicillin dosage form

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2124499A1 (fr) * 1971-02-05 1972-09-22 Squibb & Sons Inc
US3969524A (en) * 1974-08-13 1976-07-13 Hoffmann-La Roche Inc. Stable amoxicillin dosage form

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2532849A1 (fr) * 1982-09-10 1984-03-16 Glaxo Group Ltd Composition pharmaceutique solide contenant des antibiotiques b-lactamiques, son procede de preparation et procede pour stabiliser une composition pharmaceutique
EP0303223A3 (en) * 1987-08-10 1990-11-28 Fujisawa Pharmaceutical Co., Ltd. Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
US5104866A (en) * 1987-08-10 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Water-soluble antibiotic composition and water-soluble salts of cephem compounds
WO2006072577A1 (fr) * 2005-01-07 2006-07-13 Sandoz Ag Procede de preparation de granules comprenant de l’amoxicilline

Also Published As

Publication number Publication date
FR2445833B1 (fr) 1982-02-12

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Legal Events

Date Code Title Description
ST Notification of lapse