FR2444679A2 - 1-Ethyl or (iso)propyl tetra:hydro-pyridin-4-yl indole - are antidepressants, neuroleptics and antiemetics - Google Patents
1-Ethyl or (iso)propyl tetra:hydro-pyridin-4-yl indole - are antidepressants, neuroleptics and antiemeticsInfo
- Publication number
- FR2444679A2 FR2444679A2 FR7836168A FR7836168A FR2444679A2 FR 2444679 A2 FR2444679 A2 FR 2444679A2 FR 7836168 A FR7836168 A FR 7836168A FR 7836168 A FR7836168 A FR 7836168A FR 2444679 A2 FR2444679 A2 FR 2444679A2
- Authority
- FR
- France
- Prior art keywords
- neuroleptics
- antiemetics
- ethyl
- indole
- antidepressants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003474 anti-emetic effect Effects 0.000 title abstract 2
- 239000000935 antidepressant agent Substances 0.000 title abstract 2
- 229940005513 antidepressants Drugs 0.000 title abstract 2
- 229940125683 antiemetic agent Drugs 0.000 title abstract 2
- 239000002111 antiemetic agent Substances 0.000 title abstract 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 title abstract 2
- -1 1-Ethyl Chemical group 0.000 title 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention claims 3-(1-substd.-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivs. (I) as novel cpds. In (I) R is H and X is ethyl or isopropyl or R = methoxy and X = propyl. (I) are anti-depressants, neuroleptics and antiemetics. The cpds. may be administered orally (5-200 mg/day), parenterally or rectally.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7836168A FR2444679A2 (en) | 1978-12-22 | 1978-12-22 | 1-Ethyl or (iso)propyl tetra:hydro-pyridin-4-yl indole - are antidepressants, neuroleptics and antiemetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7836168A FR2444679A2 (en) | 1978-12-22 | 1978-12-22 | 1-Ethyl or (iso)propyl tetra:hydro-pyridin-4-yl indole - are antidepressants, neuroleptics and antiemetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2444679A2 true FR2444679A2 (en) | 1980-07-18 |
| FR2444679B2 FR2444679B2 (en) | 1982-09-17 |
Family
ID=9216468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7836168A Granted FR2444679A2 (en) | 1978-12-22 | 1978-12-22 | 1-Ethyl or (iso)propyl tetra:hydro-pyridin-4-yl indole - are antidepressants, neuroleptics and antiemetics |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2444679A2 (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2227873A1 (en) * | 1973-05-04 | 1974-11-29 | Boehringer Sohn Ingelheim |
-
1978
- 1978-12-22 FR FR7836168A patent/FR2444679A2/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2227873A1 (en) * | 1973-05-04 | 1974-11-29 | Boehringer Sohn Ingelheim |
Non-Patent Citations (1)
| Title |
|---|
| EXBK/75 * |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2444679B2 (en) | 1982-09-17 |
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