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FR2442M - L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. - Google Patents

L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.

Info

Publication number
FR2442M
FR2442M FR912469A FR912469A FR2442M FR 2442 M FR2442 M FR 2442M FR 912469 A FR912469 A FR 912469A FR 912469 A FR912469 A FR 912469A FR 2442 M FR2442 M FR 2442M
Authority
FR
France
Prior art keywords
derivatives
nervous system
central nervous
new central
system depressants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR912469A
Other languages
English (en)
Inventor
Henry Eugene Jean-Mari Meunier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR912469A priority Critical patent/FR2442M/fr
Priority to US314892A priority patent/US3301754A/en
Priority to GB40450/63A priority patent/GB980279A/en
Priority to US331103A priority patent/US3325361A/en
Application granted granted Critical
Publication of FR2442M publication Critical patent/FR2442M/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR912469A 1962-10-17 1962-10-17 L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. Expired FR2442M (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR912469A FR2442M (fr) 1962-10-17 1962-10-17 L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.
US314892A US3301754A (en) 1962-10-17 1963-10-09 Methods and compositions for potentiating central nervous system depressants
GB40450/63A GB980279A (en) 1962-10-17 1963-10-14 Improvements in or relating to therapeutic compositions
US331103A US3325361A (en) 1962-10-17 1963-12-17 Anticonvulsant agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR912469A FR2442M (fr) 1962-10-17 1962-10-17 L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.

Publications (1)

Publication Number Publication Date
FR2442M true FR2442M (fr) 1964-04-06

Family

ID=8788845

Family Applications (1)

Application Number Title Priority Date Filing Date
FR912469A Expired FR2442M (fr) 1962-10-17 1962-10-17 L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.

Country Status (3)

Country Link
US (2) US3301754A (fr)
FR (1) FR2442M (fr)
GB (1) GB980279A (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034172B1 (fr) * 1979-08-20 1983-05-18 Abbott Laboratories Sel melange d'acide valproique
FR2547499A1 (fr) * 1983-06-15 1984-12-21 Opochimiotherapie Lab Medicaments contenant du dipropylacetate de calcium
US4558070A (en) * 1983-10-26 1985-12-10 Abbott Laboratories Acid salts of valproic acid
US4895873A (en) * 1987-03-20 1990-01-23 Desitin Arzenimittel GmbH Calcium salt of valproic acid
US4988731A (en) * 1979-08-20 1991-01-29 Abbott Laboratories Sodium hydrogen divalproate oligomer
US5212326A (en) * 1979-08-20 1993-05-18 Abbott Laboratories Sodium hydrogen divalproate oligomer

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523155A (en) * 1967-10-03 1970-08-04 Henry E Meunier Processes for preparation of therapeutic serums
US3716552A (en) * 1969-10-09 1973-02-13 Sumitomo Chemical Co N'-alkanoyl-n''-dihalophenyl imidazolidinediones
GB1485269A (en) * 1974-06-26 1977-09-08 Labaz Pharmaceutical compositions containing acetic acid derivatives
JPS5427564A (en) * 1977-08-02 1979-03-01 Sumitomo Chem Co Ltd 1-branched alkylcarbonyl-3-(3,5-dihalogenophenyl) hydantoins, their preparation, and bactericides for pomicultural and horticultural uses containing the same as active agent.
US4238389A (en) * 1979-02-12 1980-12-09 Syva Company Valproate conjugation using dicarbonyls
IT1121282B (it) * 1979-06-08 1986-04-02 Medea Res Srl Composto ad attivita'antiepilettica e anticonvulsivante,processo per la sua preparazione e composizioni farmaceutiche relative
FR2470758A1 (fr) 1979-12-07 1981-06-12 Sanofi Sa Procede pour la fixation de groupes alkyles sur une chaine carbonee portant un groupe fonctionnel
US4301176A (en) * 1980-08-18 1981-11-17 Warner-Lambert Company Method of administering calcium valproate
LU83729A1 (fr) * 1981-11-04 1983-09-01 Galephar Sels d'acide valproique,leur preparation et leur utilisation
IL67623A (en) * 1983-01-05 1984-09-30 Teva Pharma 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
IL72381A (en) * 1983-07-20 1988-03-31 Sanofi Sa Pharmaceutical composition based on valproic acid
DE4231085A1 (de) * 1992-09-12 1994-03-17 Desitin Arzneimittel Gmbh VPA-analoge Antiepileptika
EP0632008B1 (fr) * 1993-06-01 1998-02-04 Ono Pharmaceutical Co., Ltd. Dérivés de l'acide pentanoique
US6300373B1 (en) 1993-09-10 2001-10-09 American Biogenetic Sciences, Inc. Antiproliferative and neurotrophic molecules
US5672746A (en) 1994-08-30 1997-09-30 American Biogenetic Sciences, Inc. Antiproliferative and neurotrophic molecules
IT1285801B1 (it) * 1996-10-10 1998-06-24 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione dell'acido valproico
CN1310622A (zh) 1998-06-22 2001-08-29 美国生物基因科学有限公司 丙戊酸类似物在治疗和预防偏头痛与情感性疾病中的应用
US6610326B2 (en) * 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets
US20040105886A1 (en) * 2001-02-16 2004-06-03 Chih-Ming Chen Divalproex sodium tablets
US20050276848A1 (en) * 2004-06-15 2005-12-15 Nilobon Podhipleux Sustained release neutralized divalproex sodium
US7713550B2 (en) * 2004-06-15 2010-05-11 Andrx Corporation Controlled release sodium valproate formulation
US9050302B2 (en) 2013-03-01 2015-06-09 Jazz Pharmaceuticals Ireland Limited Method of administration of gamma hydroxybutyrate with monocarboxylate transporters
CN114763319B (zh) * 2022-05-16 2023-03-31 湖南大学 一种联产丙戊酰胺和丙戊酸钠的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB672475A (en) * 1950-06-13 1952-05-21 Specific Pharmaceuticals Inc Bismuth salt of di-n-propyl acetic acid

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034172B1 (fr) * 1979-08-20 1983-05-18 Abbott Laboratories Sel melange d'acide valproique
US4988731A (en) * 1979-08-20 1991-01-29 Abbott Laboratories Sodium hydrogen divalproate oligomer
US5212326A (en) * 1979-08-20 1993-05-18 Abbott Laboratories Sodium hydrogen divalproate oligomer
FR2547499A1 (fr) * 1983-06-15 1984-12-21 Opochimiotherapie Lab Medicaments contenant du dipropylacetate de calcium
US4558070A (en) * 1983-10-26 1985-12-10 Abbott Laboratories Acid salts of valproic acid
US4895873A (en) * 1987-03-20 1990-01-23 Desitin Arzenimittel GmbH Calcium salt of valproic acid

Also Published As

Publication number Publication date
US3325361A (en) 1967-06-13
GB980279A (en) 1965-01-13
US3301754A (en) 1967-01-31

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