FR23C1023I2 - Anticorps anti-il-36r - Google Patents
Anticorps anti-il-36rInfo
- Publication number
- FR23C1023I2 FR23C1023I2 FR23C1023C FR23C1023C FR23C1023I2 FR 23C1023 I2 FR23C1023 I2 FR 23C1023I2 FR 23C1023 C FR23C1023 C FR 23C1023C FR 23C1023 C FR23C1023 C FR 23C1023C FR 23C1023 I2 FR23C1023 I2 FR 23C1023I2
- Authority
- FR
- France
- Prior art keywords
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229940099539 IL-36 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
- G01N2333/7155—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/20—Dermatological disorders
- G01N2800/205—Scaling palpular diseases, e.g. psoriasis, pytiriasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161560554P | 2011-11-16 | 2011-11-16 | |
US201261644111P | 2012-05-08 | 2012-05-08 | |
US201261713713P | 2012-10-15 | 2012-10-15 | |
PCT/US2012/064933 WO2013074569A1 (en) | 2011-11-16 | 2012-11-14 | Anti il-36r antibodies |
Publications (2)
Publication Number | Publication Date |
---|---|
FR23C1023I1 FR23C1023I1 (fr) | 2023-07-21 |
FR23C1023I2 true FR23C1023I2 (fr) | 2024-03-29 |
Family
ID=47215803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR23C1023C Active FR23C1023I2 (fr) | 2011-11-16 | 2023-05-31 | Anticorps anti-il-36r |
Country Status (39)
Country | Link |
---|---|
US (4) | US9023995B2 (ko) |
EP (2) | EP3536710A1 (ko) |
JP (3) | JP6289375B2 (ko) |
KR (3) | KR102159109B1 (ko) |
CN (5) | CN112812183B (ko) |
AP (1) | AP2014007571A0 (ko) |
AR (1) | AR089178A1 (ko) |
AU (1) | AU2012339734B2 (ko) |
BR (1) | BR112014011594B1 (ko) |
CA (1) | CA2852994C (ko) |
CL (1) | CL2014001123A1 (ko) |
CO (1) | CO7020871A2 (ko) |
CY (2) | CY1122278T1 (ko) |
DK (1) | DK2780373T3 (ko) |
EA (1) | EA031948B1 (ko) |
EC (1) | ECSP14004976A (ko) |
ES (1) | ES2755732T3 (ko) |
FI (1) | FIC20230020I1 (ko) |
FR (1) | FR23C1023I2 (ko) |
HR (1) | HRP20191835T1 (ko) |
HU (2) | HUE047437T2 (ko) |
IL (2) | IL232100B (ko) |
LT (2) | LT2780373T (ko) |
MX (1) | MX347164B (ko) |
MY (1) | MY195289A (ko) |
NL (1) | NL301233I2 (ko) |
NO (2) | NO2023024I1 (ko) |
PE (1) | PE20142041A1 (ko) |
PH (1) | PH12014501108B1 (ko) |
PL (1) | PL2780373T3 (ko) |
PT (1) | PT2780373T (ko) |
RS (1) | RS59248B1 (ko) |
SG (1) | SG11201402283PA (ko) |
SI (1) | SI2780373T1 (ko) |
TW (1) | TWI573804B (ko) |
UA (1) | UA115540C2 (ko) |
UY (1) | UY34456A (ko) |
WO (1) | WO2013074569A1 (ko) |
ZA (1) | ZA201402491B (ko) |
Families Citing this family (45)
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EP3885366A3 (en) | 2011-01-14 | 2021-12-29 | The Regents of the University of California | Therapeutic antibodies against ror-1 protein and methods for use of same |
ES2755732T3 (es) | 2011-11-16 | 2020-04-23 | Boehringer Ingelheim Int | Anticuerpos anti IL-36R |
ME02928B (me) | 2012-02-24 | 2018-04-20 | Abbvie Stemcentrx Llc | Dll3 modulatori i metode upotrebe |
US20150259420A1 (en) * | 2014-03-14 | 2015-09-17 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
RU2582569C2 (ru) * | 2014-07-24 | 2016-04-27 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Днк, кодирующая полноразмерный антагонист рецептора интерлейкина-36 человека, днк, кодирующая полноразмерный антагонист рецептора интерлейкина-36 человека с с-концевым полигистидиновым тагом, плазмидный экспрессионный вектор (варианты), штамм бактерий escherichia coli bl21 star[de3] (рет-il36raf), - продуцент полноразмерного рецепторного антагониста интерлейкина-36 и штамм бактерий escherichia coli bl21 star[de3] (pet-il36raf-his), - продуцент полноразмерного рецепторного антагониста интерлейкина-36 с с-концевым полигистидиновым тагом |
SG11201707705UA (en) | 2015-04-01 | 2017-10-30 | Anaptysbio Inc | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
MX2017013080A (es) | 2015-04-15 | 2018-02-09 | Anaptysbio Inc | Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r). |
EP3307772B1 (en) * | 2015-06-12 | 2020-09-09 | Ludwig Institute For Cancer Research Limited | Tgf-beta 3 specific antibodies and methods and uses thereof |
JP6654773B2 (ja) * | 2015-12-25 | 2020-02-26 | 国立大学法人名古屋大学 | インターロイキン36受容体アンタゴニスト欠損症の治療薬 |
BR112019008861A2 (pt) | 2016-11-01 | 2019-07-09 | Anaptysbio Inc | anticorpos direcionados contra imunoglobulina de células t e proteína de mucina 3 (tim-3) |
SG10201913083SA (en) | 2017-01-09 | 2020-03-30 | Tesaro Inc | Methods of treating cancer with anti-tim-3 antibodies |
EP3601350A1 (en) * | 2017-03-27 | 2020-02-05 | Boehringer Ingelheim International GmbH | Anti il-36r antibodies combination therapy |
US11207294B2 (en) * | 2018-01-08 | 2021-12-28 | Chemocentryx, Inc. | Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2 |
WO2019177888A1 (en) * | 2018-03-14 | 2019-09-19 | Boehringer Ingelheim International Gmbh | Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis |
WO2019177883A2 (en) * | 2018-03-14 | 2019-09-19 | Boehringer Ingelheim International Gmbh | Use of anti-il-36r antibodies for treatment of inflammatory bowel disease |
BR112020027015A2 (pt) * | 2018-07-16 | 2021-04-06 | Regeneron Pharmaceuticals, Inc. | Proteína de ligação a antígeno isolada, anticorpo ou fragmento de ligação a antígeno do mesmo, complexo, método para produzir uma proteína de ligação a antígeno, proteína de ligação a antígeno ou cadeia de imunoglobulina, polipeptídeo, polinucleotídeo, vetor, célula hospedeira, composição ou kit, composição farmacêutica, recipiente ou dispositivo de injeção, e, método para tratar ou prevenir doenças |
US11589562B2 (en) | 2018-07-16 | 2023-02-28 | Regeneran Pharmaceuticals, Inc. | Mouse model of DITRA disease and uses thereof |
EP3837283B1 (en) | 2018-08-16 | 2024-04-17 | Cantargia AB | Anti-il1rap antibody compositions |
US20210380675A1 (en) * | 2018-09-28 | 2021-12-09 | Kyowa Kirin Co., Ltd. | Il-36 antibodies and uses thereof |
AU2019405782A1 (en) * | 2018-12-21 | 2021-06-17 | 23Andme, Inc. | Anti-IL-36 antibodies and methods of use thereof |
TW202037604A (zh) * | 2018-12-27 | 2020-10-16 | 德商百靈佳殷格翰國際股份有限公司 | 治療掌蹠膿疱症之抗il-36r抗體 |
KR20210137520A (ko) * | 2019-03-08 | 2021-11-17 | 베링거 인겔하임 인터내셔날 게엠베하 | 항-il-36r 항체 제형 |
WO2021112196A1 (ja) * | 2019-12-05 | 2021-06-10 | 学校法人東京薬科大学 | 筋組織の減少を抑制するための組成物 |
AR120913A1 (es) * | 2019-12-27 | 2022-03-30 | Teijin Pharma Ltd | Anticuerpo que inhibe específicamente la señalización de il-36r |
EP4153233A1 (en) | 2020-05-19 | 2023-03-29 | Boehringer Ingelheim International GmbH | Anti-il-36r antibodies for the treatment of atopic dermatitis |
EP4182022A1 (en) | 2020-07-17 | 2023-05-24 | Boehringer Ingelheim International GmbH | Anti-il-36r antibodies for the treatment of neutrophilic dermatoses |
IL299648A (en) * | 2020-07-30 | 2023-03-01 | Anaptysbio Inc | Anti-interleukin 36 receptor therapy for psoriasis |
WO2022026829A1 (en) | 2020-07-30 | 2022-02-03 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for skin toxicity |
MX2023003723A (es) | 2020-09-30 | 2023-04-24 | Boehringer Ingelheim Int | Anticuerpos anti-il-36r para el tratamiento de dolor inflamatorio cronico. |
CN112094349B (zh) * | 2020-11-04 | 2021-02-09 | 上海华奥泰生物药业股份有限公司 | 靶向于白介素36r的抗体及其制备方法和应用 |
CN116685605A (zh) | 2020-12-17 | 2023-09-01 | 上海华奥泰生物药业股份有限公司 | 靶向il-17a和il-36r的双特异性抗体及其应用 |
WO2022150642A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa |
WO2022150644A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for acne |
WO2022166977A1 (zh) * | 2021-02-08 | 2022-08-11 | 上海普铭生物科技有限公司 | 抗人il-36r抗体及其应用 |
BR112023014103A2 (pt) | 2021-03-04 | 2023-10-10 | Boehringer Ingelheim Int | Métodos para o tratamento de gpp |
WO2022192531A2 (en) | 2021-03-12 | 2022-09-15 | Boehringer Ingelheim International Gmbh | Biomarkers associated with anti-il-36r antibody treatment in generalized pustular psoriasis |
BR112023017717A2 (pt) * | 2021-05-03 | 2024-01-09 | Boehringer Ingelheim Int | Método para produção de espesolimabe |
BR112023026429A2 (pt) * | 2021-06-18 | 2024-03-05 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Anticorpo anti-il-36r isolado ou um fragmento de ligação ao antígeno deste, imunoconjugado ou molécula multiespecífica, composição farmacêutica, método para inibir a transdução de sinal de il-36/il-36r e método para tratar doenças e condições relacionadas mediadas por il-36/il-36r em um sujeito em necessidade |
WO2023285362A1 (en) | 2021-07-12 | 2023-01-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of il-36 inhibitors for the treatment of netherton syndrome |
WO2023019232A1 (en) | 2021-08-13 | 2023-02-16 | Boehringer Ingelheim International Gmbh | Anti-il-36r antibodies for the treatment of a fibrotic condition |
JP2024537724A (ja) | 2021-09-28 | 2024-10-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 目に見える皮膚発現を有する好中球性皮膚疾患の重症度を評価するためのシステム及び方法 |
WO2023077091A1 (en) * | 2021-10-28 | 2023-05-04 | Abbvie Inc. | Anti-amyloid beta antibodies and methods of using the same |
CN115724975A (zh) * | 2022-10-20 | 2023-03-03 | 江苏荃信生物医药股份有限公司 | 抗人白介素36受体单克隆抗体及其应用 |
TW202502379A (zh) | 2023-03-09 | 2025-01-16 | 德商百靈佳殷格翰國際股份有限公司 | 抗il-36r抗體用於治療化膿性汗腺炎(hs)之用途 |
TW202515606A (zh) | 2023-06-09 | 2025-04-16 | 德商百靈佳殷格翰國際股份有限公司 | 用於治療及預防全身型膿疱性乾癬之方法 |
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