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FR2388558A1 - Procede de preparation de solutions injectables a base d'une association sulfamide-potentiateur - Google Patents

Procede de preparation de solutions injectables a base d'une association sulfamide-potentiateur

Info

Publication number
FR2388558A1
FR2388558A1 FR7712761A FR7712761A FR2388558A1 FR 2388558 A1 FR2388558 A1 FR 2388558A1 FR 7712761 A FR7712761 A FR 7712761A FR 7712761 A FR7712761 A FR 7712761A FR 2388558 A1 FR2388558 A1 FR 2388558A1
Authority
FR
France
Prior art keywords
water
trimethoprim
propylene glycol
sulpha
prepn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7712761A
Other languages
English (en)
Other versions
FR2388558B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vetoquinol SA
Original Assignee
Vetoquinol SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vetoquinol SA filed Critical Vetoquinol SA
Priority to FR7712761A priority Critical patent/FR2388558A1/fr
Priority to DE19782818281 priority patent/DE2818281A1/de
Publication of FR2388558A1 publication Critical patent/FR2388558A1/fr
Application granted granted Critical
Publication of FR2388558B1 publication Critical patent/FR2388558B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

a. Procédé de préparation d'une solution injectable qui consiste à mettre en solution, dans un milieu solubilisant, une association d'un sulfamidé sous la forme de l'un de ses sels hydrosolubles physiologiquement acceptables, notamment la sulfaméthoxypyndazine, et d'un potentiateur approprié, notamment le triméthoprim. b. Il se caractérise dans le fait que le milieu solubilisant est constitué par un mélange d'eau, de 1,2-propylèneglycol et de diméthylacétamide. c. Ce procédé permet la préparation de solutions injectables à activite anti-bactérienne.
FR7712761A 1977-04-27 1977-04-27 Procede de preparation de solutions injectables a base d'une association sulfamide-potentiateur Granted FR2388558A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7712761A FR2388558A1 (fr) 1977-04-27 1977-04-27 Procede de preparation de solutions injectables a base d'une association sulfamide-potentiateur
DE19782818281 DE2818281A1 (de) 1977-04-27 1978-04-26 Sulfamethoxypyridazin-trimethoprim- assoziat-konzentrat oder -loesung und verfahren zu ihrer herstellung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7712761A FR2388558A1 (fr) 1977-04-27 1977-04-27 Procede de preparation de solutions injectables a base d'une association sulfamide-potentiateur

Publications (2)

Publication Number Publication Date
FR2388558A1 true FR2388558A1 (fr) 1978-11-24
FR2388558B1 FR2388558B1 (fr) 1981-01-09

Family

ID=9189998

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7712761A Granted FR2388558A1 (fr) 1977-04-27 1977-04-27 Procede de preparation de solutions injectables a base d'une association sulfamide-potentiateur

Country Status (2)

Country Link
DE (1) DE2818281A1 (fr)
FR (1) FR2388558A1 (fr)

Also Published As

Publication number Publication date
FR2388558B1 (fr) 1981-01-09
DE2818281A1 (de) 1978-11-02

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Legal Events

Date Code Title Description
ST Notification of lapse