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FR2368452A1 - Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques - Google Patents

Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques

Info

Publication number
FR2368452A1
FR2368452A1 FR7803365A FR7803365A FR2368452A1 FR 2368452 A1 FR2368452 A1 FR 2368452A1 FR 7803365 A FR7803365 A FR 7803365A FR 7803365 A FR7803365 A FR 7803365A FR 2368452 A1 FR2368452 A1 FR 2368452A1
Authority
FR
France
Prior art keywords
analysis
application
biological fluids
derivatives
carbamates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7803365A
Other languages
English (en)
Other versions
FR2368452B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Union Carbide Corp
Original Assignee
Union Carbide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Carbide Corp filed Critical Union Carbide Corp
Publication of FR2368452A1 publication Critical patent/FR2368452A1/fr
Application granted granted Critical
Publication of FR2368452B1 publication Critical patent/FR2368452B1/fr
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne des dérivés marqués à l'iode radio-actif qui servent à l'analyse de divers composés des fluides biologiques. Ces dérivés sont obtenus par réaction d'un composé tel qu'un stéroïde ou une hormone, avec un isocyanate hydroxylé protégé, élimination du groupe protecteur et radio-iodation. Ces derivés permettent l'analyse des réactions antigène-anticorps dans le sang, d'une manière quantitative par comptage de désintégrations. Application à l'analyse du sang.
FR7803365A 1976-05-17 1978-02-07 Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques Expired FR2368452B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/687,149 US4115539A (en) 1976-05-17 1976-05-17 Analytical or clinical derivatives, tagged derivatives and methods of analysis using such derivatives

Publications (2)

Publication Number Publication Date
FR2368452A1 true FR2368452A1 (fr) 1978-05-19
FR2368452B1 FR2368452B1 (fr) 1985-09-06

Family

ID=24759277

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7714947A Granted FR2369284A1 (fr) 1976-05-17 1977-05-16 Produits de reaction d'isocyanates silyles avec des composes interessants du point de vue chimiqu
FR7803364A Granted FR2368453A1 (fr) 1976-05-17 1978-02-07 Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique
FR7803365A Expired FR2368452B1 (fr) 1976-05-17 1978-02-07 Derives radio-iodes de carbamates hydroxyles et leur application a l'analyse de fluides biologiques

Family Applications Before (2)

Application Number Title Priority Date Filing Date
FR7714947A Granted FR2369284A1 (fr) 1976-05-17 1977-05-16 Produits de reaction d'isocyanates silyles avec des composes interessants du point de vue chimiqu
FR7803364A Granted FR2368453A1 (fr) 1976-05-17 1978-02-07 Carbamates hydroxyles provenant de la reaction d'isocyanates avec des composes interessants du point de vue chimique

Country Status (13)

Country Link
US (1) US4115539A (fr)
JP (2) JPS5315359A (fr)
AU (1) AU519191B2 (fr)
BE (1) BE854692A (fr)
BR (1) BR7703146A (fr)
CA (1) CA1093486A (fr)
DE (1) DE2722038C2 (fr)
DK (1) DK213177A (fr)
FR (3) FR2369284A1 (fr)
GB (2) GB1586185A (fr)
IL (1) IL52095A0 (fr)
NL (1) NL7705411A (fr)
SE (2) SE447025B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433509A1 (fr) * 1978-08-17 1980-03-14 Sheludyakov Viktor Procede de preparation d'isocyanates

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256833A (en) * 1979-01-08 1981-03-17 Majid Ali Enzyme immunoassay for allergic disorders
US4358435A (en) * 1980-06-09 1982-11-09 The Research Foundation Of State University Of New York Ligand compositions and processes for their manufacture and their use in radioimmunoassay
US4670406A (en) * 1984-01-06 1987-06-02 Becton Dickinson And Company Tracers for use in assays
US4595656A (en) * 1984-01-06 1986-06-17 Becton Dickinson & Company Coupling agents and products produced therefrom
ES8801129A1 (es) * 1984-07-05 1987-12-16 Nelson Jerald C Celula para dialisis.
US4736046A (en) * 1985-12-23 1988-04-05 The Dow Chemical Company β-isocyanato organosilanes
GB9625895D0 (en) 1996-12-13 1997-01-29 Riley Patrick A Novel compound useful as therapeutic agents and assay reagents
WO2002008174A1 (fr) * 2000-07-26 2002-01-31 Patrick Anthony Riley Derives de phenylethylamine et leur utilisation dans le traitement de melanome
ES2857626T3 (es) 2010-01-15 2021-09-29 Suzhou Neupharma Co Ltd Ciertas entidades químicas, composiciones y métodos
WO2012027957A1 (fr) 2010-08-28 2012-03-08 Suzhou Neupharma Co., Ltd. Dérivés de bufaline, compositions pharmaceutiques et utilisation de ceux-ci
EP2670763B1 (fr) 2011-02-02 2018-08-01 Suzhou Neupharma Co., Ltd Certaines entités chimiques, compositions et procédés
EP3453713B1 (fr) 2012-04-29 2021-09-08 Neupharma, Inc. Dérivés bufadiènolides substitués en position 3 par un groupement amine pour le traitement du cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2285613A1 (fr) * 1974-09-11 1976-04-16 Abbott Lab Dosage radio-immunologique competitif de la digoxine dans le serum
US3963697A (en) * 1974-08-29 1976-06-15 Curtis Nuclear Corporation Labelled cardiotonic glycosides for use in radioimmunoassay

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953431A (en) * 1971-05-24 1976-04-27 Becton, Dickinson & Company Derivatives of digoxigenin
US3996344A (en) * 1972-05-15 1976-12-07 Biological Developments, Inc. Phenethylamine antigenic conjugates, their preparation, antibodies and use
US3843696A (en) * 1972-09-05 1974-10-22 Syva Co Methadone analog compounds
US3878187A (en) * 1972-09-11 1975-04-15 Syva Co Polypeptide derivatives of amphetamine and analogs for immunoassays
US3867366A (en) * 1972-11-06 1975-02-18 Synvar Associates A K A Syva C Opiate imidates and protein conjugates thereof
US3888866A (en) * 1973-06-01 1975-06-10 Syva Co Nitrogen derivatives of benzoyl ecgonine
SE396478B (sv) * 1974-04-03 1977-09-19 Pharmacia Ab Radioaktivt merkt antigen, hapten eller antikropp for anvendning vid radioimmunologiska bestemningsmetoder

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963697A (en) * 1974-08-29 1976-06-15 Curtis Nuclear Corporation Labelled cardiotonic glycosides for use in radioimmunoassay
FR2285613A1 (fr) * 1974-09-11 1976-04-16 Abbott Lab Dosage radio-immunologique competitif de la digoxine dans le serum

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433509A1 (fr) * 1978-08-17 1980-03-14 Sheludyakov Viktor Procede de preparation d'isocyanates

Also Published As

Publication number Publication date
AU2518777A (en) 1978-11-23
SE8205750D0 (sv) 1982-10-08
FR2368453B1 (fr) 1981-10-02
AU519191B2 (en) 1981-11-19
FR2368453A1 (fr) 1978-05-19
JPS5315359A (en) 1978-02-13
FR2369284B1 (fr) 1981-10-02
GB1586185A (en) 1981-03-18
CA1093486A (fr) 1981-01-13
BE854692A (fr) 1977-11-16
SE447025B (sv) 1986-10-20
DE2722038A1 (de) 1977-12-15
JPS5823699A (ja) 1983-02-12
DK213177A (da) 1977-11-18
DE2722038C2 (de) 1983-05-19
JPS6332356B2 (fr) 1988-06-29
FR2369284A1 (fr) 1978-05-26
BR7703146A (pt) 1978-04-04
GB1586186A (en) 1981-03-18
SE8205750L (sv) 1982-10-08
IL52095A0 (en) 1977-07-31
FR2368452B1 (fr) 1985-09-06
NL7705411A (nl) 1977-11-21
SE446738B (sv) 1986-10-06
SE7705191L (sv) 1977-11-18
US4115539A (en) 1978-09-19

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TP Transmission of property
ST Notification of lapse