FR2259588A1 - O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects - Google Patents
O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effectsInfo
- Publication number
- FR2259588A1 FR2259588A1 FR7403288A FR7403288A FR2259588A1 FR 2259588 A1 FR2259588 A1 FR 2259588A1 FR 7403288 A FR7403288 A FR 7403288A FR 7403288 A FR7403288 A FR 7403288A FR 2259588 A1 FR2259588 A1 FR 2259588A1
- Authority
- FR
- France
- Prior art keywords
- acid
- antiinflammatory
- esters
- salts
- analgesic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
O-Malylsalicylic acid, its salts and esters are of formula (I) (where R' and R2 are H, alkali or alkaline eath metal cations, Al, opt. substd. aliphatic or aromatic amines, quat. ammonium ions, residues of amino acids or opt. substd. aminoalcohols, or R2 may be the group The cpds. have antipyretic and analgesic action of salicylic acid and are free of toxic actions, e.g. induction of tinnitus. The antiinflammatory and decongestant action of alicylic acid is improved by the presence in the molecule of a constituent of the Krebs cycle.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7403288A FR2259588A1 (en) | 1974-01-31 | 1974-01-31 | O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7403288A FR2259588A1 (en) | 1974-01-31 | 1974-01-31 | O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2259588A1 true FR2259588A1 (en) | 1975-08-29 |
FR2259588B1 FR2259588B1 (en) | 1977-09-09 |
Family
ID=9134303
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7403288A Granted FR2259588A1 (en) | 1974-01-31 | 1974-01-31 | O-malylsalicyclic acid, esters and salts - with antiinflammatory, analgesic and antipyretic activity and reduced side-effects |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2259588A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2374039A1 (en) * | 1976-12-15 | 1978-07-13 | Procter & Gamble | COMPOSITIONS CONTAINING A DERIVATIVE OF SALICYLIC ACID AND MEDICINAL APPLICATIONS |
WO2015043688A1 (en) * | 2013-09-27 | 2015-04-02 | Ratiopharm Gmbh | Prodrugs of monomethyl fumarate (mmf) |
-
1974
- 1974-01-31 FR FR7403288A patent/FR2259588A1/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2374039A1 (en) * | 1976-12-15 | 1978-07-13 | Procter & Gamble | COMPOSITIONS CONTAINING A DERIVATIVE OF SALICYLIC ACID AND MEDICINAL APPLICATIONS |
WO2015043688A1 (en) * | 2013-09-27 | 2015-04-02 | Ratiopharm Gmbh | Prodrugs of monomethyl fumarate (mmf) |
Also Published As
Publication number | Publication date |
---|---|
FR2259588B1 (en) | 1977-09-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |