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FR2250793A1 - - Google Patents

Info

Publication number
FR2250793A1
FR2250793A1 FR7340002A FR7340002A FR2250793A1 FR 2250793 A1 FR2250793 A1 FR 2250793A1 FR 7340002 A FR7340002 A FR 7340002A FR 7340002 A FR7340002 A FR 7340002A FR 2250793 A1 FR2250793 A1 FR 2250793A1
Authority
FR
France
Prior art keywords
nov
inclusions
hydrophobic polymeric
substrate
polymeric substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7340002A
Other languages
French (fr)
Other versions
FR2250793B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR7340002A priority Critical patent/FR2250793B1/fr
Priority to CH1465574A priority patent/CH606208A5/xx
Priority to GB47545/74A priority patent/GB1486288A/en
Priority to CA213,032A priority patent/CA1049954A/en
Priority to BE150263A priority patent/BE821909A/en
Priority to IL46010A priority patent/IL46010A/en
Priority to SU742075365A priority patent/SU1060119A3/en
Priority to ZA00747123A priority patent/ZA747123B/en
Priority to JP12882474A priority patent/JPS5639780B2/ja
Priority to IT70296/74A priority patent/IT1024789B/en
Priority to DE2453155A priority patent/DE2453155C2/en
Priority to SE7414081A priority patent/SE419967B/en
Priority to ES431778A priority patent/ES431778A1/en
Priority to NL7414588.A priority patent/NL164874C/en
Publication of FR2250793A1 publication Critical patent/FR2250793A1/fr
Priority to US05/737,453 priority patent/US4196065A/en
Application granted granted Critical
Publication of FR2250793B1 publication Critical patent/FR2250793B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C08J7/16—Chemical modification with polymerisable compounds
    • C08J7/18—Chemical modification with polymerisable compounds using wave energy or particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/38—Graft polymerization

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Graft Or Block Polymers (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

1486288 Sustained release of medicaments COMMISSARIAT A L'ENERGIE ATOMIQUE 4 Nov 1974 [9 Nov 1973] 47545/74 Heading A5B [Also in Division C3] A hydrophobic polymeric substrate has cross-linked polymerised hydrophilic inclusions derived from an hydrophilic ethylenically unsaturated monomer grafted to the substrate and distributed throughout the volume thereof and has a medicament, soluble in polar solvents, stored in said inclusions and desorbable therefrom on contacting the hydrophobic polymeric substrate with a polar solvent.
FR7340002A 1973-11-09 1973-11-09 Expired FR2250793B1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR7340002A FR2250793B1 (en) 1973-11-09 1973-11-09
CH1465574A CH606208A5 (en) 1973-11-09 1974-11-01
GB47545/74A GB1486288A (en) 1973-11-09 1974-11-04 Hydrophobic substrates having grafted hydrophilic inclusions containing polar soluble substances
CA213,032A CA1049954A (en) 1973-11-09 1974-11-05 Hydrophobic substrate with grafted hydrophilic inclusions
IL46010A IL46010A (en) 1973-11-09 1974-11-06 Hydrophobic poylmerized substrates comprising grafted hydrophilic inclusions containing polar solvent-soluble substrates and their production
SU742075365A SU1060119A3 (en) 1973-11-09 1974-11-06 Process for preparing polymeric absorbent substrate
ZA00747123A ZA747123B (en) 1973-11-09 1974-11-06 A method for the volumetric inclusion and grafting of hydrophilic compounds in a hydrophobic substrate
BE150263A BE821909A (en) 1973-11-09 1974-11-06 HYDROPHOBIC SUBSTRATE CONTAINING GRAFT HYDROPHILIC INCLUSIONS
JP12882474A JPS5639780B2 (en) 1973-11-09 1974-11-08
IT70296/74A IT1024789B (en) 1973-11-09 1974-11-08 POLYMER WATER-REPELLENT SUBSTRATE CONTAINING HYDROPHILIC INCLUSIONS PARTICULARLY USEFUL AS A SELECTIVE PERNEABILITY MEMBRANE
DE2453155A DE2453155C2 (en) 1973-11-09 1974-11-08 Method for reversibly storing a substance in a polymerized hydrophobic substrate
SE7414081A SE419967B (en) 1973-11-09 1974-11-08 SET IN A POLYMERIZED HYDROPHOBAT SUBSTRATE STORAGE A SOLID SUBSTANCE IN A POLISHED SOLVENT AND RELEASE THE SUBSTANCE FROM THE SUBSTRATE
ES431778A ES431778A1 (en) 1973-11-09 1974-11-08 Hydrophobic substrates having grafted hydrophilic inclusions containing polar soluble substances
NL7414588.A NL164874C (en) 1973-11-09 1974-11-08 METHOD FOR STORING A SUBSTANCE IN A POLYMER SUBSTRATE WHICH CAN BE FREED OUT OF THIS SUBSTRATE LATER.
US05/737,453 US4196065A (en) 1973-11-09 1976-11-01 Hydrophobic substrate with grafted hydrophilic inclusions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7340002A FR2250793B1 (en) 1973-11-09 1973-11-09

Publications (2)

Publication Number Publication Date
FR2250793A1 true FR2250793A1 (en) 1975-06-06
FR2250793B1 FR2250793B1 (en) 1978-12-29

Family

ID=9127552

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7340002A Expired FR2250793B1 (en) 1973-11-09 1973-11-09

Country Status (14)

Country Link
JP (1) JPS5639780B2 (en)
BE (1) BE821909A (en)
CA (1) CA1049954A (en)
CH (1) CH606208A5 (en)
DE (1) DE2453155C2 (en)
ES (1) ES431778A1 (en)
FR (1) FR2250793B1 (en)
GB (1) GB1486288A (en)
IL (1) IL46010A (en)
IT (1) IT1024789B (en)
NL (1) NL164874C (en)
SE (1) SE419967B (en)
SU (1) SU1060119A3 (en)
ZA (1) ZA747123B (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433949A1 (en) * 1978-08-25 1980-03-21 Commissariat Energie Atomique HYDROPHOBIC SUBSTRATE CAPABLE OF RELEASING A CHEMICAL SUBSTANCE
FR2436606A1 (en) * 1978-09-25 1980-04-18 Jenapharm Veb PHARMACEUTICAL EXCIPIENT PRODUCT, ITS PREPARATION AND ITS USE IN THE PREPARATION OF SOLID DRUG FORMS
EP0043319A1 (en) * 1980-06-30 1982-01-06 COMMISSARIAT A L'ENERGIE ATOMIQUE Etablissement de Caractère Scientifique Technique et Industriel Inert support made of a reticulated copolymer, method of preparing it, and its use in making sustained-release drugs
FR2505879A1 (en) * 1981-05-15 1982-11-19 Chloe Chemie DIAPHRAGM, PROCESS FOR PREPARING THE SAME, AND ELECTROLYSIS METHOD FOR CARRYING OUT THE SAME
FR2513256A1 (en) * 1981-09-18 1983-03-25 Commissariat Energie Atomique ELASTOMER SEPARATOR ELEMENT, PROCESS FOR PREPARING THE SAME AND USE THEREOF IN HYDROPNEUMATIC SUSPENSION SYSTEMS
EP0033262B1 (en) * 1980-01-29 1986-12-30 Elf Atochem S.A. Electrolysis diaphragm and method for its manufacture
EP0229019A2 (en) * 1986-01-07 1987-07-15 Mitsubishi Rayon Co., Ltd. Hydrophilized porous membrane and production process thereof
EP0299063A1 (en) * 1987-01-28 1989-01-18 Membrex Inc Hydrophilic article and method of producing same.
EP0342239A1 (en) * 1987-11-04 1989-11-23 Mitsubishi Rayon Co., Ltd Porous membrane and process for its production
EP0463627A2 (en) * 1990-06-29 1992-01-02 Gore Enterprise Holdings, Inc. Hydrophylized microporous polytetrafluorethylene membrane and production process thereof
EP0526203A1 (en) * 1991-07-30 1993-02-03 Tonen Chemical Corporation Separation membrane
FR2699406A1 (en) * 1992-12-21 1994-06-24 Commissariat Energie Atomique Copolymer-based films, their applications in transdermal systems and their methods of preparation

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2311792A1 (en) * 1975-05-20 1976-12-17 Anvar Acrylic acid grafted PVC sheet - used for selectively permeable membrane
JPS5477661A (en) * 1977-12-02 1979-06-21 Teijin Ltd Crosslinked or uncrosslinked linear aromatic polyester composition and its production
JPH0323530B2 (en) * 1979-03-21 1991-03-29 Nat Res Dev
JPS5969570U (en) * 1982-10-29 1984-05-11 日本電気ホームエレクトロニクス株式会社 display device
GB2186485B (en) * 1986-02-13 1988-09-07 Ethical Pharma Ltd Slow release formulation
US4897433A (en) * 1986-12-08 1990-01-30 Japan Atomic Energy Research Inst. Process for producing an anti-thrombogenic material by graft polymerization
US4906374A (en) * 1986-12-23 1990-03-06 Pall Corporation Filtration media with low protein adsorbability
US4959150A (en) * 1988-09-26 1990-09-25 Pall Corporation Fluid treatment system having low affinity for proteinaceous materials
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2056057A5 (en) * 1969-08-26 1971-05-14 Raffinage Cie Francaise
JPS4934302A (en) * 1972-07-27 1974-03-29

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2433949A1 (en) * 1978-08-25 1980-03-21 Commissariat Energie Atomique HYDROPHOBIC SUBSTRATE CAPABLE OF RELEASING A CHEMICAL SUBSTANCE
EP0009423A1 (en) * 1978-08-25 1980-04-02 COMMISSARIAT A L'ENERGIE ATOMIQUE Etablissement de Caractère Scientifique Technique et Industriel Hydrophobic substrate capable of liberating a chemical compound, process for its preparation and its application as an intra-uterine device
FR2436606A1 (en) * 1978-09-25 1980-04-18 Jenapharm Veb PHARMACEUTICAL EXCIPIENT PRODUCT, ITS PREPARATION AND ITS USE IN THE PREPARATION OF SOLID DRUG FORMS
EP0033262B1 (en) * 1980-01-29 1986-12-30 Elf Atochem S.A. Electrolysis diaphragm and method for its manufacture
EP0043319A1 (en) * 1980-06-30 1982-01-06 COMMISSARIAT A L'ENERGIE ATOMIQUE Etablissement de Caractère Scientifique Technique et Industriel Inert support made of a reticulated copolymer, method of preparing it, and its use in making sustained-release drugs
FR2505879A1 (en) * 1981-05-15 1982-11-19 Chloe Chemie DIAPHRAGM, PROCESS FOR PREPARING THE SAME, AND ELECTROLYSIS METHOD FOR CARRYING OUT THE SAME
FR2513256A1 (en) * 1981-09-18 1983-03-25 Commissariat Energie Atomique ELASTOMER SEPARATOR ELEMENT, PROCESS FOR PREPARING THE SAME AND USE THEREOF IN HYDROPNEUMATIC SUSPENSION SYSTEMS
EP0077227A1 (en) * 1981-09-18 1983-04-20 Commissariat à l'Energie Atomique Elastomeric separator membrane, its preparation process and its use in hydropneumatic suspension systems
EP0229019A3 (en) * 1986-01-07 1989-02-01 Mitsubishi Rayon Co. Ltd. Hydrophilized porous membrane and production process thereof
EP0229019A2 (en) * 1986-01-07 1987-07-15 Mitsubishi Rayon Co., Ltd. Hydrophilized porous membrane and production process thereof
EP0299063A1 (en) * 1987-01-28 1989-01-18 Membrex Inc Hydrophilic article and method of producing same.
EP0299063A4 (en) * 1987-01-28 1989-10-11 Membrex Inc Hydrophilic article and method of producing same.
EP0342239A1 (en) * 1987-11-04 1989-11-23 Mitsubishi Rayon Co., Ltd Porous membrane and process for its production
EP0342239A4 (en) * 1987-11-04 1990-01-08 Mitsubishi Rayon Co Porous membrane and process for its production.
EP0463627A2 (en) * 1990-06-29 1992-01-02 Gore Enterprise Holdings, Inc. Hydrophylized microporous polytetrafluorethylene membrane and production process thereof
EP0463627A3 (en) * 1990-06-29 1992-05-20 Chemie Ag Bitterfeld-Wolfen Hydrophylized microporous polytetrafluorethylene membrane and production process thereof
EP0526203A1 (en) * 1991-07-30 1993-02-03 Tonen Chemical Corporation Separation membrane
FR2699406A1 (en) * 1992-12-21 1994-06-24 Commissariat Energie Atomique Copolymer-based films, their applications in transdermal systems and their methods of preparation
WO1994014425A1 (en) * 1992-12-21 1994-07-07 Commissariat A L'energie Atomique Copolymer-based films, applications thereof in transdermal systems and processes for their preparation
US5556635A (en) * 1992-12-21 1996-09-17 Spi-Bio Films based on copolymers, their applications in transdermal systems and their processes of preparation

Also Published As

Publication number Publication date
ZA747123B (en) 1976-03-31
NL164874B (en) 1980-09-15
SE7414081L (en) 1976-05-10
CH606208A5 (en) 1978-10-31
IT1024789B (en) 1978-07-20
GB1486288A (en) 1977-09-21
ES431778A1 (en) 1977-05-16
FR2250793B1 (en) 1978-12-29
CA1049954A (en) 1979-03-06
IL46010A (en) 1978-09-29
NL164874C (en) 1981-02-16
DE2453155C2 (en) 1986-01-30
SE419967B (en) 1981-09-07
NL7414588A (en) 1975-05-13
JPS5639780B2 (en) 1981-09-16
DE2453155A1 (en) 1975-05-15
IL46010A0 (en) 1975-05-22
SU1060119A3 (en) 1983-12-07
BE821909A (en) 1975-03-03
JPS50112479A (en) 1975-09-03

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Legal Events

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TP Transmission of property
CL Concession to grant licences
TP Transmission of property
TP Transmission of property
TP Transmission of property
TP Transmission of property