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FR2198736A1 - 4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity - Google Patents

4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity

Info

Publication number
FR2198736A1
FR2198736A1 FR7232370A FR7232370A FR2198736A1 FR 2198736 A1 FR2198736 A1 FR 2198736A1 FR 7232370 A FR7232370 A FR 7232370A FR 7232370 A FR7232370 A FR 7232370A FR 2198736 A1 FR2198736 A1 FR 2198736A1
Authority
FR
France
Prior art keywords
alkyl
formula
quinolines
antiinflammatory
thienyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7232370A
Other languages
French (fr)
Other versions
FR2198736B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7232370A priority Critical patent/FR2198736A1/en
Priority to ES418688A priority patent/ES418688A1/en
Publication of FR2198736A1 publication Critical patent/FR2198736A1/en
Application granted granted Critical
Publication of FR2198736B1 publication Critical patent/FR2198736B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Antinflammatory and analgesic agents of formula (where R' is H, halogen 1-5C alkyl, alkoxy or alkylthio, CF3, OCF3, -SCF3, NO2, CN, 1-5C alkylamino, 1-5C alkyl sulphonyloxy acylamino; R2 is H, CI, CH3; Y is a gp. of formula (i) (iii):- where R3 is H or 1-3C alkyl; X is H; 1-6C alkyl; phenyl; a gp of formula -(CH2).N(Z')2 or where Z' gps singly are 1-6C alkyl or together form 4-5C alkylene; M is 1-6C alkyl; n = 1-6 Z2 is halogen; or X is morpholinoalkyl (1-6C alkyl); 2,3-dihydroxypropyl; a gp -CH2 where P' and P2 are 1-5C alkyl or a gp having the formula P3 where P3 is 1-6C alkyl, and their acid-addn salts, excepting (I; R2 is H; R' is 8-CF3; Y is (I) or (II); and X is H, CH3, 2,3-dihydroxypropyl or 2,3-dihydroxypropyl acetonide).
FR7232370A 1972-09-13 1972-09-13 4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity Granted FR2198736A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7232370A FR2198736A1 (en) 1972-09-13 1972-09-13 4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity
ES418688A ES418688A1 (en) 1972-09-13 1973-09-12 A procedure to prepare new derivatives of quinolein. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7232370A FR2198736A1 (en) 1972-09-13 1972-09-13 4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity

Publications (2)

Publication Number Publication Date
FR2198736A1 true FR2198736A1 (en) 1974-04-05
FR2198736B1 FR2198736B1 (en) 1975-11-28

Family

ID=9104196

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7232370A Granted FR2198736A1 (en) 1972-09-13 1972-09-13 4-(Carboxy thienyl) quinolines - with antiinflammatory and analgesic activity

Country Status (2)

Country Link
ES (1) ES418688A1 (en)
FR (1) FR2198736A1 (en)

Also Published As

Publication number Publication date
ES418688A1 (en) 1976-02-16
FR2198736B1 (en) 1975-11-28

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Legal Events

Date Code Title Description
ST Notification of lapse