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FR2148400A1 - Halocyclobutane anaesthetics - for inhalation - Google Patents

Halocyclobutane anaesthetics - for inhalation

Info

Publication number
FR2148400A1
FR2148400A1 FR7141576A FR7141576A FR2148400A1 FR 2148400 A1 FR2148400 A1 FR 2148400A1 FR 7141576 A FR7141576 A FR 7141576A FR 7141576 A FR7141576 A FR 7141576A FR 2148400 A1 FR2148400 A1 FR 2148400A1
Authority
FR
France
Prior art keywords
anaesthetics
inhalation
halocyclobutane
chz2
xhc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7141576A
Other languages
French (fr)
Other versions
FR2148400B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GCP Products UK Ltd
WR Grace and Co Conn
Original Assignee
WR Grace Ltd
WR Grace and Co Conn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WR Grace Ltd, WR Grace and Co Conn filed Critical WR Grace Ltd
Publication of FR2148400A1 publication Critical patent/FR2148400A1/en
Application granted granted Critical
Publication of FR2148400B1 publication Critical patent/FR2148400B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C23/00—Compounds containing at least one halogen atom bound to a ring other than a six-membered aromatic ring
    • C07C23/02—Monocyclic halogenated hydrocarbons
    • C07C23/06—Monocyclic halogenated hydrocarbons with a four-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
    • C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
    • C07C17/206—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being HX
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
    • C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
    • C07C17/208—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being MX
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/23—Preparation of halogenated hydrocarbons by dehalogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/272—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions
    • C07C17/275—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions of hydrocarbons and halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/272—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions
    • C07C17/278—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions of only halogenated hydrocarbons

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel cpds. of formula (I) (where X=F or Me) e.g. 1-chloro-2,4,4-trifluoro cyclobutane are inhalation anaesthetics, which do not provoke convulsions. They are prepd. by reacting a cpd. Z'HC=CF2 with XHC=CHZ2 (where Z1, Z2 are H or Cl).
FR7141576A 1971-08-09 1971-11-19 Halocyclobutane anaesthetics - for inhalation Granted FR2148400A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17033171A 1971-08-09 1971-08-09
US17029471A 1971-08-09 1971-08-09
US17028071A 1971-08-09 1971-08-09

Publications (2)

Publication Number Publication Date
FR2148400A1 true FR2148400A1 (en) 1973-03-23
FR2148400B1 FR2148400B1 (en) 1975-02-07

Family

ID=27389798

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7141576A Granted FR2148400A1 (en) 1971-08-09 1971-11-19 Halocyclobutane anaesthetics - for inhalation

Country Status (7)

Country Link
JP (1) JPS4828453A (en)
AR (2) AR193628A1 (en)
BE (1) BE775619A (en)
BR (1) BR7107739D0 (en)
DE (1) DE2157399A1 (en)
FR (1) FR2148400A1 (en)
NL (1) NL7115894A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5728463Y2 (en) * 1976-07-09 1982-06-21
JP2006225292A (en) * 2005-02-16 2006-08-31 National Institute Of Advanced Industrial & Technology 1,1,2,2,3,3-hexafluorocyclobutane and method for producing the same
JP4919270B2 (en) * 2006-08-07 2012-04-18 独立行政法人産業技術総合研究所 1,2-dichloro-3,3,4,4-tetrafluorocyclobutane and method for producing the same
JP4919283B2 (en) * 2007-03-28 2012-04-18 独立行政法人産業技術総合研究所 Fluorine-containing cyclic compound and method for producing the same
EP3329966B1 (en) 2012-07-10 2021-12-22 The Regents of The University of California Methods of inducing anesthesia
US20160113887A1 (en) 2014-06-05 2016-04-28 The Regents Of The University Of California Halogenated ether compounds and methods of inducing anesthesia

Also Published As

Publication number Publication date
NL7115894A (en) 1973-02-13
AR194497A1 (en) 1973-07-23
FR2148400B1 (en) 1975-02-07
DE2157399A1 (en) 1973-02-22
JPS4828453A (en) 1973-04-14
BR7107739D0 (en) 1973-04-12
AR193628A1 (en) 1973-05-11
BE775619A (en) 1972-05-19

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Legal Events

Date Code Title Description
ST Notification of lapse