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FR2073251A1 - Flavanol polyacid complexes - useful for stabilizing and purifying flavanol monomers for antiscorbutic use - Google Patents

Flavanol polyacid complexes - useful for stabilizing and purifying flavanol monomers for antiscorbutic use

Info

Publication number
FR2073251A1
FR2073251A1 FR6941644A FR6941644A FR2073251A1 FR 2073251 A1 FR2073251 A1 FR 2073251A1 FR 6941644 A FR6941644 A FR 6941644A FR 6941644 A FR6941644 A FR 6941644A FR 2073251 A1 FR2073251 A1 FR 2073251A1
Authority
FR
France
Prior art keywords
flavanol
complexes
useful
monomers
antiscorbutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6941644A
Other languages
French (fr)
Other versions
FR2073251B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THERAPEUTI BUREAU ET
Original Assignee
THERAPEUTI BUREAU ET
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by THERAPEUTI BUREAU ET filed Critical THERAPEUTI BUREAU ET
Priority to FR6941644A priority Critical patent/FR2073251A1/en
Publication of FR2073251A1 publication Critical patent/FR2073251A1/en
Application granted granted Critical
Publication of FR2073251B1 publication Critical patent/FR2073251B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Complexes are made from flavanol monomers and polyacids chosen from organic polyacid-alcohols, phosphoric acid, and boric acid. These complexes arer stable and thus useful in preserving the flavanol monomers for antiscorbutic use. If the complexes are made from several flavanol monomers and polymers in a mixture, the complexes can be selectively dissolved in different solvents, and this is a useful method for purifying flavanols. The preferred polyacids are citric and tartaric acids, and the prefd. flavanols are (-)epicatechin and leucoanthocyanidol.
FR6941644A 1969-12-03 1969-12-03 Flavanol polyacid complexes - useful for stabilizing and purifying flavanol monomers for antiscorbutic use Granted FR2073251A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6941644A FR2073251A1 (en) 1969-12-03 1969-12-03 Flavanol polyacid complexes - useful for stabilizing and purifying flavanol monomers for antiscorbutic use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6941644A FR2073251A1 (en) 1969-12-03 1969-12-03 Flavanol polyacid complexes - useful for stabilizing and purifying flavanol monomers for antiscorbutic use

Publications (2)

Publication Number Publication Date
FR2073251A1 true FR2073251A1 (en) 1971-10-01
FR2073251B1 FR2073251B1 (en) 1974-08-09

Family

ID=9043994

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6941644A Granted FR2073251A1 (en) 1969-12-03 1969-12-03 Flavanol polyacid complexes - useful for stabilizing and purifying flavanol monomers for antiscorbutic use

Country Status (1)

Country Link
FR (1) FR2073251A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166861A (en) * 1976-03-23 1979-09-04 Inverni Della Beffa S.P.A. Pharmacologically active polyphenolic substances
EP0263132A4 (en) * 1986-04-07 1988-11-16 Clemetson Ab Charles Catechin coated ascorbic acid and method.
EP0275224A3 (en) * 1987-01-14 1989-09-27 Indena S.P.A. Phospholipidic complexes of vitis vinifera extracts, process for their preparation and pharmaceutical and cosmetic compositions containing them

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166861A (en) * 1976-03-23 1979-09-04 Inverni Della Beffa S.P.A. Pharmacologically active polyphenolic substances
EP0263132A4 (en) * 1986-04-07 1988-11-16 Clemetson Ab Charles Catechin coated ascorbic acid and method.
EP0275224A3 (en) * 1987-01-14 1989-09-27 Indena S.P.A. Phospholipidic complexes of vitis vinifera extracts, process for their preparation and pharmaceutical and cosmetic compositions containing them

Also Published As

Publication number Publication date
FR2073251B1 (en) 1974-08-09

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