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FR2016718A1 - Anti inflammatory 2 methyl 3 (2 (2diethylaminoethoxy) - phenyl) quinazolin 4 one - Google Patents

Anti inflammatory 2 methyl 3 (2 (2diethylaminoethoxy) - phenyl) quinazolin 4 one

Info

Publication number
FR2016718A1
FR2016718A1 FR6929508A FR6929508A FR2016718A1 FR 2016718 A1 FR2016718 A1 FR 2016718A1 FR 6929508 A FR6929508 A FR 6929508A FR 6929508 A FR6929508 A FR 6929508A FR 2016718 A1 FR2016718 A1 FR 2016718A1
Authority
FR
France
Prior art keywords
quinazolin
phenyl
methyl
anti inflammatory
provoked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6929508A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Troponwerke Dinklage and Co
Meda Manufacturing GmbH
Original Assignee
Troponwerke Dinklage and Co
Tropon GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Dinklage and Co, Tropon GmbH filed Critical Troponwerke Dinklage and Co
Publication of FR2016718A1 publication Critical patent/FR2016718A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Anti-inflammatory 2-methyl-3-(2-(2-diethylaminoethoxy) phenyl)-quinazolin-4-one. M3A. Has formula (I): and in expts. on kaolin-provoked oedema in the rat paw, it is as active as 1,2-diphenyl-4-n-butyl-3,5-dioxopyrazolidine when given orally at the rate of 10-100 mg./kg. and more active than this cpd., against albumin- or formalin-provoked oedema. Clinical results show (I) to have little toxicity and to be well tolerated.
FR6929508A 1968-08-31 1969-08-28 Anti inflammatory 2 methyl 3 (2 (2diethylaminoethoxy) - phenyl) quinazolin 4 one Withdrawn FR2016718A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6271868 1968-08-31

Publications (1)

Publication Number Publication Date
FR2016718A1 true FR2016718A1 (en) 1970-05-08

Family

ID=13208386

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6929508A Withdrawn FR2016718A1 (en) 1968-08-31 1969-08-28 Anti inflammatory 2 methyl 3 (2 (2diethylaminoethoxy) - phenyl) quinazolin 4 one

Country Status (4)

Country Link
BE (1) BE737950A (en)
DE (1) DE1939109A1 (en)
ES (1) ES370743A1 (en)
FR (1) FR2016718A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1717230A1 (en) * 2004-02-13 2006-11-02 Banyu Pharmaceutical Co., Ltd. Fused-ring 4-oxopyrimidine derivative

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3166627D1 (en) * 1980-12-12 1984-11-15 Thomae Gmbh Dr K Pyrimidones, their preparation and medicines containing them
WO2006085692A1 (en) 2005-02-14 2006-08-17 Banyu Pharmaceutical Co., Ltd Crystal of 4(3h)-quinazolinone derivative

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1717230A1 (en) * 2004-02-13 2006-11-02 Banyu Pharmaceutical Co., Ltd. Fused-ring 4-oxopyrimidine derivative
EP1717230A4 (en) * 2004-02-13 2009-09-23 Banyu Pharma Co Ltd 4-OXOPYRIMIDIN DERIVATIVE WITH CONDENSED RING
US8268842B2 (en) 2004-02-13 2012-09-18 Msd K.K. Fused ring 4-oxopyrimidine derivative

Also Published As

Publication number Publication date
BE737950A (en) 1970-02-25
DE1939109A1 (en) 1970-03-05
ES370743A1 (en) 1971-07-01

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Legal Events

Date Code Title Description
ST Notification of lapse