FR16C1000I2 - COMPOSITIONS COMPRISING POLYPEPTIDES - Google Patents
COMPOSITIONS COMPRISING POLYPEPTIDESInfo
- Publication number
- FR16C1000I2 FR16C1000I2 FR16C1000C FR16C1000C FR16C1000I2 FR 16C1000 I2 FR16C1000 I2 FR 16C1000I2 FR 16C1000 C FR16C1000 C FR 16C1000C FR 16C1000 C FR16C1000 C FR 16C1000C FR 16C1000 I2 FR16C1000 I2 FR 16C1000I2
- Authority
- FR
- France
- Prior art keywords
- polypeptides
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03027511 | 2003-11-28 | ||
| PCT/EP2004/013445 WO2005052004A2 (en) | 2003-11-28 | 2004-11-26 | Compositions comprising polypeptides |
| EP04803302A EP1691833B1 (en) | 2003-11-28 | 2004-11-26 | Compositions comprising polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR16C1000I1 FR16C1000I1 (en) | 2016-06-24 |
| FR16C1000I2 true FR16C1000I2 (en) | 2017-02-03 |
Family
ID=34626385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR16C1000C Active FR16C1000I2 (en) | 2003-11-28 | 2016-05-20 | COMPOSITIONS COMPRISING POLYPEPTIDES |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US10000574B2 (en) |
| EP (2) | EP2186527A1 (en) |
| AT (1) | ATE459374T1 (en) |
| AU (1) | AU2004293182B2 (en) |
| BE (1) | BE2016C023I2 (en) |
| CA (1) | CA2544532C (en) |
| CY (2) | CY1110689T1 (en) |
| DE (1) | DE602004025840D1 (en) |
| DK (1) | DK1691833T3 (en) |
| ES (1) | ES2341252T3 (en) |
| FR (1) | FR16C1000I2 (en) |
| HU (1) | HUS1600019I1 (en) |
| LU (1) | LU93067I2 (en) |
| NL (1) | NL300807I2 (en) |
| PL (1) | PL1691833T3 (en) |
| PT (1) | PT1691833E (en) |
| SI (1) | SI1691833T1 (en) |
| WO (1) | WO2005052004A2 (en) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2383297T3 (en) | 2006-08-14 | 2013-06-28 | Xencor Inc | Optimized antibodies that target CD19 |
| WO2008031056A2 (en) * | 2006-09-08 | 2008-03-13 | Medimmune, Llc | Humanized anti-cd19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
| WO2009070642A1 (en) * | 2007-11-28 | 2009-06-04 | Medimmune, Llc | Protein formulation |
| US8796420B2 (en) | 2009-12-31 | 2014-08-05 | Avidbiotics Corp. | Non-natural MIC proteins |
| US8658765B2 (en) | 2009-12-31 | 2014-02-25 | Avidbiotics Corp. | Non-natural MIC proteins |
| DK2632954T4 (en) | 2010-10-27 | 2021-08-09 | Amgen Res Munich Gmbh | MEDICINES AND METHODS FOR THE TREATMENT OF DLBCL |
| CA2830349C (en) | 2011-03-17 | 2019-07-16 | The University Of Birmingham | Re-directed immunotherapy |
| EP2699596A4 (en) | 2011-04-22 | 2015-01-14 | Emergent Product Dev Seattle | Prostate-specific membrane antigen binding proteins and related compositions and methods |
| GB201203442D0 (en) | 2012-02-28 | 2012-04-11 | Univ Birmingham | Immunotherapeutic molecules and uses |
| WO2015095410A1 (en) | 2013-12-17 | 2015-06-25 | Genentech, Inc. | Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody |
| SG11201604956SA (en) | 2013-12-17 | 2016-07-28 | Genentech Inc | Methods of treating cancers using pd-1 axis binding antagonists and taxanes |
| EA035419B9 (en) | 2014-05-29 | 2020-08-07 | Мэкроудженикс, Инк. | Tri-specific binding molecules and methods of use thereof |
| EP3215525B1 (en) | 2014-11-05 | 2020-07-29 | Genentech, Inc. | Methods of producing two chain proteins in bacteria |
| CN108064308B (en) | 2014-11-05 | 2023-06-09 | 豪夫迈·罗氏有限公司 | Method for producing two-chain proteins in bacteria |
| AU2016215604B2 (en) | 2015-02-02 | 2020-08-13 | The University Of Birmingham | Targeting moiety peptide epitope complexes having a plurality of T-cell epitopes |
| EP3303619B1 (en) | 2015-05-29 | 2020-06-10 | H. Hoffnabb-La Roche Ag | Pd-l1 promoter methylation in cancer |
| CA2986263A1 (en) | 2015-06-17 | 2016-12-22 | Genentech, Inc. | Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes |
| US11352426B2 (en) | 2015-09-21 | 2022-06-07 | Aptevo Research And Development Llc | CD3 binding polypeptides |
| AR106188A1 (en) | 2015-10-01 | 2017-12-20 | Hoffmann La Roche | ANTI-CD19 HUMANIZED HUMAN ANTIBODIES AND METHODS OF USE |
| EP3377103B2 (en) | 2015-11-19 | 2025-03-12 | Revitope Limited | Functional antibody fragment complementation for a two-components system for redirected killing of unwanted cells |
| BR112018003984A2 (en) | 2015-12-09 | 2018-09-25 | Hoffmann La Roche | antibodies |
| EP3178848A1 (en) | 2015-12-09 | 2017-06-14 | F. Hoffmann-La Roche AG | Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies |
| BR112018011029A2 (en) | 2016-01-08 | 2018-11-21 | Hoffmann La Roche | methods for treating or delaying cancer progression and improving immune function in a cancer individual, uses of a binding antagonist and a bispecific antibody, compositions and kits |
| EP3252078A1 (en) | 2016-06-02 | 2017-12-06 | F. Hoffmann-La Roche AG | Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer |
| BR112019022558A2 (en) | 2016-06-02 | 2020-05-19 | Hoffmann La Roche | antibodies, methods to treat or slow the progression of a proliferative disease and to treat or slow the progression of cancer in an individual, pharmaceutical compositions, kit, uses of a combination of an anti-cd20 antibody and an antibody and invention |
| JP2019530434A (en) | 2016-08-05 | 2019-10-24 | ジェネンテック， インコーポレイテッド | Multivalent and multi-epitope antibodies with agonist activity and methods of use |
| WO2018029124A1 (en) | 2016-08-08 | 2018-02-15 | F. Hoffmann-La Roche Ag | Therapeutic and diagnostic methods for cancer |
| EP3554542A1 (en) | 2016-12-19 | 2019-10-23 | H. Hoffnabb-La Roche Ag | Combination therapy with targeted 4-1bb (cd137) agonists |
| ES2847973T3 (en) | 2016-12-20 | 2021-08-04 | Hoffmann La Roche | Combination of bispecific anti-CD20 / anti-CD3 antibodies and 4-1BB (CD137) agonists |
| CA3079036A1 (en) | 2017-11-01 | 2019-05-09 | F. Hoffmann-La Roche Ag | Combination therapy with targeted ox40 agonists |
| AU2019236372B2 (en) | 2018-03-13 | 2024-06-20 | F. Hoffmann-La Roche Ag | Therapeutic combination of 4-1 BB agonists with anti-CD20 antibodies |
| TWI841551B (en) | 2018-03-13 | 2024-05-11 | 瑞士商赫孚孟拉羅股份公司 | Combination therapy with targeted 4-1bb (cd137) agonists |
| AU2019282836A1 (en) * | 2018-06-07 | 2021-01-07 | Cullinan Oncology, Inc. | Multi-specific binding proteins and methods of use thereof |
| CA3111809A1 (en) | 2018-09-21 | 2020-03-26 | Genentech, Inc. | Diagnostic methods for triple-negative breast cancer |
| AU2019375413A1 (en) | 2018-11-05 | 2021-05-27 | Genentech, Inc. | Methods of producing two chain proteins in prokaryotic host cells |
| WO2020221792A1 (en) | 2019-04-30 | 2020-11-05 | Amgen Research (Munich) Gmbh | Means and methods of treating burkitt lymphoma or leukemia |
| BR112021022682A2 (en) | 2019-05-14 | 2022-02-22 | Provention Bio Inc | Methods and compositions for preventing type 1 diabetes |
| KR20220010544A (en) | 2019-05-21 | 2022-01-25 | 노파르티스 아게 | CD19 binding molecules and uses thereof |
| CA3182445A1 (en) | 2020-06-11 | 2021-12-16 | Francisco Leon | Methods and compositions for preventing type 1 diabetes |
| MX2022015877A (en) | 2020-06-16 | 2023-01-24 | Genentech Inc | Methods and compositions for treating triple-negative breast cancer. |
| KR102453073B1 (en) * | 2020-08-14 | 2022-10-11 | 건국대학교 글로컬산학협력단 | Method for preparation of bispecific antibody using Pichia Pastoris and bispecific antibody prepared thereby |
| WO2022169825A1 (en) | 2021-02-03 | 2022-08-11 | Mozart Therapeutics, Inc. | Binding agents and methods of using the same |
| WO2022217022A1 (en) | 2021-04-10 | 2022-10-13 | Profoundbio Us Co. | Folr1 binding agents, conjugates thereof and methods of using the same |
| JP2024516631A (en) | 2021-04-23 | 2024-04-16 | プロファウンドバイオ ユーエス カンパニー | Anti-CD70 antibodies, conjugates thereof and methods of using same |
| KR20240005722A (en) | 2021-04-30 | 2024-01-12 | 에프. 호프만-라 로슈 아게 | Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies |
| EP4083061A1 (en) * | 2021-04-30 | 2022-11-02 | Kilometro Rosso SPA | Fusion proteins and use thereof in the treatment of membranous nephropathy |
| CA3213632A1 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate |
| TW202320857A (en) | 2021-07-06 | 2023-06-01 | 美商普方生物製藥美國公司 | Linkers, drug linkers and conjugates thereof and methods of using the same |
| WO2023076876A1 (en) | 2021-10-26 | 2023-05-04 | Mozart Therapeutics, Inc. | Modulation of immune responses to viral vectors |
| EP4496631A1 (en) | 2022-03-23 | 2025-01-29 | F. Hoffmann-La Roche AG | Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy |
| EP4508081A1 (en) | 2022-04-13 | 2025-02-19 | F. Hoffmann-La Roche AG | Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use |
| WO2024030956A2 (en) | 2022-08-03 | 2024-02-08 | Mozart Therapeutics, Inc. | Cd39-specific binding agents and methods of using the same |
| WO2024094741A1 (en) | 2022-11-03 | 2024-05-10 | F. Hoffmann-La Roche Ag | Combination therapy with anti-cd19/anti-cd28 bispecific antibody |
| WO2024243423A1 (en) | 2023-05-24 | 2024-11-28 | Mozart Therapeutics, Inc. | Cd8-specific binding proteins and methods of using the same |
| WO2024261013A1 (en) | 2023-06-21 | 2024-12-26 | F. Hoffmann-La Roche Ag | Combination therapy with fap-targeted lymphotoxin beta receptor agonists |
| WO2025072406A1 (en) | 2023-09-26 | 2025-04-03 | Profoundbio Us Co. | Ptk7 binding agents, conjugates thereof and methods of using the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| DE3856559T2 (en) | 1987-05-21 | 2004-04-29 | Micromet Ag | Multifunctional proteins with predetermined objectives |
| US5258498A (en) | 1987-05-21 | 1993-11-02 | Creative Biomolecules, Inc. | Polypeptide linkers for production of biosynthetic proteins |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| EP0573551B1 (en) | 1991-02-27 | 2003-05-21 | Micromet AG | Serine-rich peptide linkers |
| US5525491A (en) | 1991-02-27 | 1996-06-11 | Creative Biomolecules, Inc. | Serine-rich peptide linkers |
| US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
| ID27512A (en) * | 1998-04-21 | 2001-04-12 | Microment Ges Fur Biomedizinis | PRIVATE POLIPEPTIDES CD19XCD3 AND ITS USES |
| US20020142964A1 (en) * | 2000-11-02 | 2002-10-03 | Nissen Torben Lauesgaard | Single-chain polypeptides |
| DK1441589T3 (en) * | 2001-11-08 | 2012-08-06 | Abbott Biotherapeutics Corp | Stable, liquid, pharmaceutical composition of IgG antibodies |
-
2004
- 2004-11-26 AT AT04803302T patent/ATE459374T1/en active
- 2004-11-26 CA CA2544532A patent/CA2544532C/en not_active Expired - Lifetime
- 2004-11-26 WO PCT/EP2004/013445 patent/WO2005052004A2/en active Application Filing
- 2004-11-26 AU AU2004293182A patent/AU2004293182B2/en not_active Expired
- 2004-11-26 EP EP10155222A patent/EP2186527A1/en not_active Withdrawn
- 2004-11-26 US US10/580,660 patent/US10000574B2/en active Active
- 2004-11-26 PL PL04803302T patent/PL1691833T3/en unknown
- 2004-11-26 EP EP04803302A patent/EP1691833B1/en not_active Expired - Lifetime
- 2004-11-26 SI SI200431360T patent/SI1691833T1/en unknown
- 2004-11-26 DE DE602004025840T patent/DE602004025840D1/en not_active Expired - Lifetime
- 2004-11-26 DK DK04803302.1T patent/DK1691833T3/en active
- 2004-11-26 ES ES04803302T patent/ES2341252T3/en not_active Expired - Lifetime
- 2004-11-26 PT PT04803302T patent/PT1691833E/en unknown
-
2010
- 2010-05-27 CY CY20101100465T patent/CY1110689T1/en unknown
-
2016
- 2016-05-03 NL NL300807C patent/NL300807I2/nl unknown
- 2016-05-05 CY CY2016010C patent/CY2016010I1/en unknown
- 2016-05-05 HU HUS1600019C patent/HUS1600019I1/en unknown
- 2016-05-10 BE BE2016C023C patent/BE2016C023I2/fr unknown
- 2016-05-11 LU LU93067C patent/LU93067I2/en unknown
- 2016-05-20 FR FR16C1000C patent/FR16C1000I2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK1691833T3 (en) | 2010-05-03 |
| SI1691833T1 (en) | 2010-06-30 |
| EP1691833A2 (en) | 2006-08-23 |
| ES2341252T3 (en) | 2010-06-17 |
| US10000574B2 (en) | 2018-06-19 |
| AU2004293182B2 (en) | 2010-02-18 |
| HUS1600019I1 (en) | 2016-06-28 |
| CY1110689T1 (en) | 2015-06-10 |
| CA2544532C (en) | 2015-06-16 |
| EP1691833B1 (en) | 2010-03-03 |
| BE2016C023I2 (en) | 2023-12-18 |
| LU93067I2 (en) | 2016-07-11 |
| US20070249529A1 (en) | 2007-10-25 |
| DE602004025840D1 (en) | 2010-04-15 |
| WO2005052004A2 (en) | 2005-06-09 |
| WO2005052004A3 (en) | 2006-03-09 |
| CY2016010I2 (en) | 2016-08-31 |
| NL300807I2 (en) | 2016-10-13 |
| AU2004293182A1 (en) | 2005-06-09 |
| PL1691833T3 (en) | 2010-08-31 |
| CY2016010I1 (en) | 2016-08-31 |
| ATE459374T1 (en) | 2010-03-15 |
| PT1691833E (en) | 2010-06-08 |
| CA2544532A1 (en) | 2005-06-09 |
| EP2186527A1 (en) | 2010-05-19 |
| FR16C1000I1 (en) | 2016-06-24 |
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