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FR11C0038I1 - MACROCYCLIC ANALOGS, THEIR METHODS OF USE AND PREPARATION - Google Patents

MACROCYCLIC ANALOGS, THEIR METHODS OF USE AND PREPARATION

Info

Publication number
FR11C0038I1
FR11C0038I1 FR11C0038C FR11C0038I1 FR 11C0038 I1 FR11C0038 I1 FR 11C0038I1 FR 11C0038 C FR11C0038 C FR 11C0038C FR 11C0038 I1 FR11C0038 I1 FR 11C0038I1
Authority
FR
France
Prior art keywords
preparation
methods
macrocyclic analogs
analogs
macrocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22219026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR11C0038(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eisai R&D Management Co Ltd filed Critical Eisai R&D Management Co Ltd
Publication of FR11C0038I1 publication Critical patent/FR11C0038I1/en
Application granted granted Critical
Publication of FR11C0038I2 publication Critical patent/FR11C0038I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention provides a compound having the formula: that is useful as an intermediate in the preparation of certain pharmaceutically active halichondrin analogs.
FR11C0038C 1998-06-17 2011-09-09 MACROCYCLIC ANALOGS, THEIR METHODS OF USE AND PREPARATION Active FR11C0038I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8968298P 1998-06-17 1998-06-17
EP99928746A EP1087960B1 (en) 1998-06-17 1999-06-16 Macrocyclic analogs and methods of their use and preparation

Publications (2)

Publication Number Publication Date
FR11C0038I1 true FR11C0038I1 (en) 2011-10-14
FR11C0038I2 FR11C0038I2 (en) 2013-01-11

Family

ID=22219026

Family Applications (1)

Application Number Title Priority Date Filing Date
FR11C0038C Active FR11C0038I2 (en) 1998-06-17 2011-09-09 MACROCYCLIC ANALOGS, THEIR METHODS OF USE AND PREPARATION

Country Status (23)

Country Link
US (4) US6214865B1 (en)
EP (4) EP1087960B1 (en)
JP (1) JP4454151B2 (en)
KR (1) KR100798600B1 (en)
CN (1) CN1216051C (en)
AT (1) ATE502932T1 (en)
AU (1) AU762998B2 (en)
BE (1) BE2011C028I2 (en)
BR (1) BRPI9911326B8 (en)
CA (3) CA2632433C (en)
CY (2) CY1111516T1 (en)
DE (2) DE69943296D1 (en)
DK (1) DK1087960T3 (en)
FR (1) FR11C0038I2 (en)
HK (1) HK1035534A1 (en)
HU (1) HU227912B1 (en)
IL (1) IL139960A0 (en)
LU (1) LU91854I2 (en)
NO (5) NO328280B1 (en)
NZ (1) NZ508597A (en)
PT (1) PT1087960E (en)
WO (1) WO1999065894A1 (en)
ZA (1) ZA200007159B (en)

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WO2012147900A1 (en) 2011-04-28 2012-11-01 Eisai R&D Management Co., Ltd. Microreactor process for halichondrin b analog synthesis
ES2705950T3 (en) 2011-06-03 2019-03-27 Eisai R&D Man Co Ltd Biomarkers to predict and assess the responsiveness of subjects with thyroid and kidney cancer to lenvatinib compounds
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Also Published As

Publication number Publication date
AU4573999A (en) 2000-01-05
CA2755266A1 (en) 1999-12-23
EP2272840B1 (en) 2012-08-22
US6214865B1 (en) 2001-04-10
RU2245335C2 (en) 2005-01-27
DE69943296D1 (en) 2011-05-05
EP1087960B1 (en) 2011-03-23
KR20010083050A (en) 2001-08-31
NO2011026I2 (en) 2012-06-11
WO1999065894A1 (en) 1999-12-23
DK1087960T3 (en) 2011-06-14
BRPI9911326B8 (en) 2021-05-25
US6365759B1 (en) 2002-04-02
HU227912B1 (en) 2012-05-29
EP1087960A4 (en) 2004-12-01
JP4454151B2 (en) 2010-04-21
NO328280B1 (en) 2010-01-25
CN1312804A (en) 2001-09-12
CY1111516T1 (en) 2014-04-09
NO2022019I1 (en) 2022-06-03
AU762998C (en) 2000-01-05
BR9911326B1 (en) 2015-01-06
CA2335300A1 (en) 1999-12-23
CN1216051C (en) 2005-08-24
CA2632433A1 (en) 1999-12-23
KR100798600B1 (en) 2008-01-28
NZ508597A (en) 2004-01-30
EP2272840A1 (en) 2011-01-12
EP2272839B1 (en) 2012-08-22
DE122011100031I1 (en) 2011-12-15
NO20006316L (en) 2001-02-15
EP2277873A1 (en) 2011-01-26
HUP0103357A2 (en) 2002-01-28
US20110172446A1 (en) 2011-07-14
PT1087960E (en) 2011-06-17
CY2011010I2 (en) 2014-04-09
NO20006316D0 (en) 2000-12-12
CA2335300C (en) 2008-10-07
CA2632433C (en) 2012-02-07
EP1087960A1 (en) 2001-04-04
ZA200007159B (en) 2001-12-04
FR11C0038I2 (en) 2013-01-11
NO331183B1 (en) 2011-10-24
HUP0103357A3 (en) 2002-10-28
LU91854I2 (en) 2011-10-17
IL139960A0 (en) 2002-02-10
NO20093217L (en) 2001-02-15
EP2272839A1 (en) 2011-01-12
JP2002518384A (en) 2002-06-25
AU762998B2 (en) 2003-07-10
CA2755266C (en) 2014-08-12
NO2011018I1 (en) 2011-09-26
EP2277873B1 (en) 2012-05-30
US8148554B2 (en) 2012-04-03
HK1035534A1 (en) 2001-11-30
CY2011010I1 (en) 2014-04-09
NO2011026I1 (en) 2012-01-09
BE2011C028I2 (en) 2018-08-24
ATE502932T1 (en) 2011-04-15
BR9911326A (en) 2001-04-03
US6469182B1 (en) 2002-10-22

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