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FI972763L - Mutant proteins - Google Patents

Mutant proteins Download PDF

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Publication number
FI972763L
FI972763L FI972763A FI972763A FI972763L FI 972763 L FI972763 L FI 972763L FI 972763 A FI972763 A FI 972763A FI 972763 A FI972763 A FI 972763A FI 972763 L FI972763 L FI 972763L
Authority
FI
Finland
Prior art keywords
mutant proteins
mutant
proteins
Prior art date
Application number
FI972763A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI972763A7 (en
FI972763A0 (en
Inventor
Joachim Hauber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9502771.0A external-priority patent/GB9502771D0/en
Priority claimed from GBGB9513505.9A external-priority patent/GB9513505D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI972763A0 publication Critical patent/FI972763A0/en
Publication of FI972763A7 publication Critical patent/FI972763A7/en
Publication of FI972763L publication Critical patent/FI972763L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI972763A 1995-02-13 1996-02-12 Mutant proteins FI972763L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502771.0A GB9502771D0 (en) 1995-02-13 1995-02-13 Organic compounds
GBGB9513505.9A GB9513505D0 (en) 1995-07-03 1995-07-03 Organic compounds
PCT/EP1996/000585 WO1996025492A1 (en) 1995-02-13 1996-02-12 EUKARYOTIC INITIATION FACTOR 5A (eIF-5A) MUTANTS

Publications (3)

Publication Number Publication Date
FI972763A0 FI972763A0 (en) 1997-06-26
FI972763A7 FI972763A7 (en) 1997-10-10
FI972763L true FI972763L (en) 1997-10-10

Family

ID=26306494

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972763A FI972763L (en) 1995-02-13 1996-02-12 Mutant proteins

Country Status (15)

Country Link
EP (1) EP0811060A1 (en)
JP (1) JPH10509327A (en)
KR (1) KR19980702160A (en)
CN (1) CN1173897A (en)
AU (1) AU4665196A (en)
BR (1) BR9606951A (en)
CA (1) CA2210538A1 (en)
CZ (1) CZ255397A3 (en)
FI (1) FI972763L (en)
HU (1) HUP9801681A3 (en)
IL (1) IL117113A0 (en)
NO (1) NO973679L (en)
PL (1) PL321239A1 (en)
SK (1) SK109997A3 (en)
WO (1) WO1996025492A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001551A2 (en) * 1997-06-30 1999-01-14 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Novel inhibitor of cellular proliferation
US7166467B2 (en) 2001-07-23 2007-01-23 Senesco Technologies, Inc. Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis
US7968523B2 (en) * 2001-07-23 2011-06-28 Senesco Technologies, Inc. Method for inducing apoptosis using apoptosis-specific EIF5-A
US7381708B2 (en) 2001-07-23 2008-06-03 Sensco Technologies, Inc. Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye
US6867237B1 (en) * 2001-07-23 2005-03-15 Senesco Technologies, Inc. DNA encoding apoptosis-induced eucaryotic initiation factor-5A and deoxyhypusine synthase and a method for controlling apoptosis in animals and humans
US7217517B2 (en) * 2001-07-23 2007-05-15 Senesco Technologies, Inc. Nucleic acids, polypeptides, and methods for modulating apoptosis
CN100558410C (en) * 2002-05-07 2009-11-11 森尼斯科技术公司 Nucleic acids, polypeptides, and methods for modulating apoptosis
EP1601767B1 (en) 2003-03-05 2012-04-25 Senesco Technologies, Inc. USE OF siRNA TO SUPPRESS EXPRESSION OF EIF-5A1 IN THE TREATMENT OF GLAUCOMA
TW200512293A (en) * 2003-06-06 2005-04-01 Senesco Technologies Inc Inhibition of apoptosis-specific eIF-5A ("eIF-5A1") with antisense oligonucleotides and siRNAs as anti-inflammatory therapeutics
CN102282259A (en) 2008-03-07 2011-12-14 森尼斯科技术公司 Use of SIRNA to achieve down regulation of an endogenous gene in combination with the use of a sense construct to achieve expression of a desired polynucleotide
US8445638B2 (en) 2008-09-03 2013-05-21 Senesco Technologies, Inc. Use of a truncated eIF-5A1 polynucleotide to induce apoptosis in cancer cells

Also Published As

Publication number Publication date
AU4665196A (en) 1996-09-04
MX9705757A (en) 1998-07-31
WO1996025492A1 (en) 1996-08-22
CA2210538A1 (en) 1996-08-22
CN1173897A (en) 1998-02-18
EP0811060A1 (en) 1997-12-10
HUP9801681A3 (en) 2000-10-30
NO973679D0 (en) 1997-08-11
SK109997A3 (en) 1998-04-08
CZ255397A3 (en) 1998-02-18
KR19980702160A (en) 1998-07-15
FI972763A7 (en) 1997-10-10
BR9606951A (en) 1997-10-28
PL321239A1 (en) 1997-11-24
JPH10509327A (en) 1998-09-14
NO973679L (en) 1997-10-13
FI972763A0 (en) 1997-06-26
HUP9801681A2 (en) 1998-10-28
IL117113A0 (en) 1996-06-18

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