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FI972763A - mutant proteins - Google Patents

mutant proteins Download PDF

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Publication number
FI972763A
FI972763A FI972763A FI972763A FI972763A FI 972763 A FI972763 A FI 972763A FI 972763 A FI972763 A FI 972763A FI 972763 A FI972763 A FI 972763A FI 972763 A FI972763 A FI 972763A
Authority
FI
Finland
Prior art keywords
mutant proteins
mutant
proteins
Prior art date
Application number
FI972763A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI972763A0 (en
Inventor
Joachim Hauber
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9502771.0A external-priority patent/GB9502771D0/en
Priority claimed from GBGB9513505.9A external-priority patent/GB9513505D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI972763A0 publication Critical patent/FI972763A0/en
Publication of FI972763A publication Critical patent/FI972763A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI972763A 1995-02-13 1997-06-26 mutant proteins FI972763A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502771.0A GB9502771D0 (en) 1995-02-13 1995-02-13 Organic compounds
GBGB9513505.9A GB9513505D0 (en) 1995-07-03 1995-07-03 Organic compounds
PCT/EP1996/000585 WO1996025492A1 (en) 1995-02-13 1996-02-12 EUKARYOTIC INITIATION FACTOR 5A (eIF-5A) MUTANTS

Publications (2)

Publication Number Publication Date
FI972763A0 FI972763A0 (en) 1997-06-26
FI972763A true FI972763A (en) 1997-10-10

Family

ID=26306494

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972763A FI972763A (en) 1995-02-13 1997-06-26 mutant proteins

Country Status (15)

Country Link
EP (1) EP0811060A1 (en)
JP (1) JPH10509327A (en)
KR (1) KR19980702160A (en)
CN (1) CN1173897A (en)
AU (1) AU4665196A (en)
BR (1) BR9606951A (en)
CA (1) CA2210538A1 (en)
CZ (1) CZ255397A3 (en)
FI (1) FI972763A (en)
HU (1) HUP9801681A3 (en)
IL (1) IL117113A0 (en)
NO (1) NO973679L (en)
PL (1) PL321239A1 (en)
SK (1) SK109997A3 (en)
WO (1) WO1996025492A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448040B1 (en) * 1997-06-20 2002-09-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibitor of cellular proliferation
US7217517B2 (en) * 2001-07-23 2007-05-15 Senesco Technologies, Inc. Nucleic acids, polypeptides, and methods for modulating apoptosis
US6867237B1 (en) * 2001-07-23 2005-03-15 Senesco Technologies, Inc. DNA encoding apoptosis-induced eucaryotic initiation factor-5A and deoxyhypusine synthase and a method for controlling apoptosis in animals and humans
US7968523B2 (en) * 2001-07-23 2011-06-28 Senesco Technologies, Inc. Method for inducing apoptosis using apoptosis-specific EIF5-A
US7166467B2 (en) * 2001-07-23 2007-01-23 Senesco Technologies, Inc. Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis
US7381708B2 (en) 2001-07-23 2008-06-03 Sensco Technologies, Inc. Suppression of eIF5A1 expression by the use of antisense oligonucleotides for the prevention of retinal cell death in the glaucomatous eye
TW200427695A (en) 2003-03-05 2004-12-16 Senesco Technologies Inc Use of antisense oligonucleotides or sirna to suppress expression of eif-5a1
AU2004258070B2 (en) * 2003-06-06 2008-12-11 Senesco Technologies, Inc. Inhibition of apoptosis-specific elF-5A ("elF-5A1") with antisense oligonucleotides and siRNAs as anti-inflammatory therapeutics
US8703929B2 (en) 2008-03-07 2014-04-22 Senesco Technologies, Inc. Compositions comprising siRNA and plasmids
US8445638B2 (en) 2008-09-03 2013-05-21 Senesco Technologies, Inc. Use of a truncated eIF-5A1 polynucleotide to induce apoptosis in cancer cells

Also Published As

Publication number Publication date
FI972763A0 (en) 1997-06-26
BR9606951A (en) 1997-10-28
KR19980702160A (en) 1998-07-15
JPH10509327A (en) 1998-09-14
CZ255397A3 (en) 1998-02-18
HUP9801681A3 (en) 2000-10-30
IL117113A0 (en) 1996-06-18
NO973679L (en) 1997-10-13
HUP9801681A2 (en) 1998-10-28
AU4665196A (en) 1996-09-04
MX9705757A (en) 1998-07-31
NO973679D0 (en) 1997-08-11
CA2210538A1 (en) 1996-08-22
EP0811060A1 (en) 1997-12-10
WO1996025492A1 (en) 1996-08-22
PL321239A1 (en) 1997-11-24
CN1173897A (en) 1998-02-18
SK109997A3 (en) 1998-04-08

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