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FI971777L - Katepsiini O2-proteaasi - Google Patents

Katepsiini O2-proteaasi Download PDF

Info

Publication number
FI971777L
FI971777L FI971777A FI971777A FI971777L FI 971777 L FI971777 L FI 971777L FI 971777 A FI971777 A FI 971777A FI 971777 A FI971777 A FI 971777A FI 971777 L FI971777 L FI 971777L
Authority
FI
Finland
Prior art keywords
cathepsin
protease
Prior art date
Application number
FI971777A
Other languages
English (en)
Swedish (sv)
Other versions
FI971777A7 (fi
FI971777A0 (fi
Inventor
Dieter Broemme
Kathleen Okamoto
Original Assignee
Arris Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26987129&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI971777(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/330,121 external-priority patent/US5736357A/en
Application filed by Arris Pharm Corp filed Critical Arris Pharm Corp
Publication of FI971777A7 publication Critical patent/FI971777A7/fi
Publication of FI971777L publication Critical patent/FI971777L/fi
Publication of FI971777A0 publication Critical patent/FI971777A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI971777A 1994-10-27 1995-10-26 Katepsiini O2-proteaasi FI971777A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/330,121 US5736357A (en) 1994-10-27 1994-10-27 Cathespin O protease
US08/536,861 US6544767B1 (en) 1994-10-27 1995-10-02 Cathespin O2 protease
PCT/US1995/013820 WO1996013523A1 (en) 1994-10-27 1995-10-26 Cathepsin o2 protease

Publications (3)

Publication Number Publication Date
FI971777A7 FI971777A7 (fi) 1997-04-25
FI971777L true FI971777L (fi) 1997-04-25
FI971777A0 FI971777A0 (fi) 1997-04-25

Family

ID=26987129

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971777A FI971777A0 (fi) 1994-10-27 1995-10-26 Katepsiini O2-proteaasi

Country Status (15)

Country Link
US (2) US6544767B1 (fi)
EP (1) EP0783527B1 (fi)
JP (1) JP3670666B2 (fi)
KR (1) KR100473219B1 (fi)
CN (1) CN1148382C (fi)
AT (1) ATE317441T1 (fi)
AU (1) AU711810B2 (fi)
CA (1) CA2203765C (fi)
DE (1) DE69534778T2 (fi)
ES (1) ES2256849T3 (fi)
FI (1) FI971777A0 (fi)
HU (1) HU220960B1 (fi)
NO (1) NO971875L (fi)
NZ (1) NZ296003A (fi)
WO (1) WO1996013523A1 (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403304B1 (en) 1993-04-06 2002-06-11 Forsyth Dental Infirmary For Children Human osteoclast-specific and -related DNA sequences
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
AU711014B2 (en) 1995-10-30 1999-10-07 Smithkline Beecham Corporation Method of inhibiting cathepsin K
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
TR199800767T2 (xx) 1995-10-30 1998-07-21 Smithkline Beecham Corporation Proteaz engelleyicileri.
EP0812916A3 (en) * 1996-06-14 1998-12-09 Smithkline Beecham Corporation Cathepsin k gene
WO1998000716A1 (en) * 1996-07-03 1998-01-08 Novadx, Inc. Method for detecting degenerative bone disease
GB9701888D0 (en) * 1997-01-30 1997-03-19 Ciba Geigy Ag Novel methods
US5948669A (en) * 1997-02-26 1999-09-07 Smithkline Beecham Corporation Rat cathepsin K polynucleotide and polypeptide sequence
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US6346373B1 (en) * 1999-05-05 2002-02-12 Merck Frosst Canada & Co., Whole cell assay for cathepsin K activity
WO2001000798A2 (en) * 1999-06-25 2001-01-04 Hybritech Incorporated Cloning and expressing of human cathepsin k in mammalian cells
EP1229914A4 (en) 1999-11-10 2004-06-23 Smithkline Beecham Corp PROTEASE INHIBITORS
EP1232154A4 (en) 1999-11-10 2004-06-23 Smithkline Beecham Corp PROTEASE INHIBITORS
WO2001034599A1 (en) 1999-11-10 2001-05-17 Smithkline Beecham Corporation Protease inhibitors
AU780364B2 (en) 2000-01-20 2005-03-17 Merck Sharp & Dohme Corp. Alpha V integrin receptor antagonists
JP2003527429A (ja) 2000-03-21 2003-09-16 スミスクライン・ビーチャム・コーポレイション プロテアーゼ阻害物質
AU2002239753A1 (en) * 2000-10-18 2002-05-21 Incyte Genomics, Inc. Proteases
CN100408681C (zh) * 2002-06-17 2008-08-06 株式会社日冷 来源于粉红色虾的新型组织蛋白酶l样半胱氨酸蛋白酶
US7101880B2 (en) * 2002-06-24 2006-09-05 Schering Aktiengesellschaft Peptidic compounds as cysteine protease inhibitors
JP2006528151A (ja) * 2003-07-21 2006-12-14 ノバルティス アクチエンゲゼルシャフト 骨転移、腫瘍増殖および腫瘍誘発骨量減少の処置におけるカテプシンk阻害剤およびビスホスホネートの組み合わせ
US7312353B2 (en) 2003-08-21 2007-12-25 Merck Frost Canada & Co. Cathespin cysteine protease inhibitors
CA2539076A1 (en) * 2003-09-23 2005-03-31 Merck Frosst Canada Ltd. Whole cell assay for inhibitors of cathepsin k
WO2005093421A1 (de) * 2004-03-10 2005-10-06 Biovendor Laboratory Medicine, Inc. Enzymimmunoassay zur bestimmung von cathepsin k
US7029902B2 (en) * 2004-03-26 2006-04-18 Applera Corporation Isolated monkey cathepsin S proteins, nucleic acid molecules encoding monkey cathepsin S proteins, and uses thereof
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
TWI395593B (zh) * 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
AU2013202011C1 (en) * 2008-03-06 2015-10-01 Halozyme, Inc. In vivo temporal control of activatable matrix-degrading enzymes
LT2953948T (lt) 2013-02-07 2018-01-10 Scifluor Life Sciences, Inc Fluorinti integrino antagonistai
US8901144B2 (en) 2013-02-07 2014-12-02 Scifluor Life Sciences, Llc Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
JP6649902B2 (ja) 2014-05-30 2020-02-19 ファイザー・インク 選択的アンドロゲン受容体モジュレーターとしてのカルボニトリル誘導体
RU2017132433A (ru) 2015-02-19 2019-03-19 Сайфлуор Лайф Сайенсиз, Инк. Фторированные производные тетрагидронафтиридинилнонановой кислоты и их применение
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
WO1997047642A1 (en) 1996-06-14 1997-12-18 Smithkline Beecham Corporation Cathepsin k gene

Also Published As

Publication number Publication date
US20030175937A1 (en) 2003-09-18
EP0783527A1 (en) 1997-07-16
DE69534778T2 (de) 2006-08-17
AU3968895A (en) 1996-05-23
CN1170415A (zh) 1998-01-14
CN1148382C (zh) 2004-05-05
FI971777A7 (fi) 1997-04-25
HU220960B1 (hu) 2002-07-29
EP0783527B1 (en) 2006-02-08
CA2203765A1 (en) 1996-05-09
CA2203765C (en) 2002-04-23
KR970707153A (ko) 1997-12-01
DE69534778D1 (en) 2006-04-20
NO971875D0 (no) 1997-04-23
WO1996013523A1 (en) 1996-05-09
NZ296003A (en) 1999-10-28
US6544767B1 (en) 2003-04-08
HUT77049A (hu) 1998-03-02
ES2256849T3 (es) 2006-07-16
EP0783527A4 (en) 1998-12-02
FI971777A0 (fi) 1997-04-25
JP3670666B2 (ja) 2005-07-13
NO971875L (no) 1997-06-12
ATE317441T1 (de) 2006-02-15
KR100473219B1 (ko) 2005-05-16
AU711810B2 (en) 1999-10-21
JPH10512740A (ja) 1998-12-08

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