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FI970959A0 - Antiviral nucleoside analogs containing a substituted benzimidazole base linked to a carbocyclic ring - Google Patents

Antiviral nucleoside analogs containing a substituted benzimidazole base linked to a carbocyclic ring

Info

Publication number
FI970959A0
FI970959A0 FI970959A FI970959A FI970959A0 FI 970959 A0 FI970959 A0 FI 970959A0 FI 970959 A FI970959 A FI 970959A FI 970959 A FI970959 A FI 970959A FI 970959 A0 FI970959 A0 FI 970959A0
Authority
FI
Finland
Prior art keywords
carbocyclic ring
nucleoside analogs
substituted benzimidazole
analogs containing
antiviral nucleoside
Prior art date
Application number
FI970959A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI970959A (en
Inventor
Leroy B Townsend
Susan Mary Daluge
Original Assignee
Wellcome Found
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/304,006 external-priority patent/US5534535A/en
Application filed by Wellcome Found, Univ Michigan filed Critical Wellcome Found
Publication of FI970959A0 publication Critical patent/FI970959A0/en
Publication of FI970959A publication Critical patent/FI970959A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI970959A 1994-09-09 1997-03-06 Antiviral nucleoside analogs containing a substituted benzimidazole base linked to a carbocyclic ring FI970959A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/304,006 US5534535A (en) 1992-03-09 1994-09-09 Therapeutic nucleosides
PCT/US1995/011366 WO1996007646A1 (en) 1994-09-09 1995-09-11 Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring

Publications (2)

Publication Number Publication Date
FI970959A0 true FI970959A0 (en) 1997-03-06
FI970959A FI970959A (en) 1997-05-06

Family

ID=23174626

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970959A FI970959A (en) 1994-09-09 1997-03-06 Antiviral nucleoside analogs containing a substituted benzimidazole base linked to a carbocyclic ring

Country Status (17)

Country Link
EP (1) EP0779885A1 (en)
JP (1) JPH10505092A (en)
CN (1) CN1164855A (en)
AP (1) AP741A (en)
AU (1) AU3692895A (en)
BR (1) BR9508826A (en)
CA (1) CA2199502A1 (en)
CZ (1) CZ71297A3 (en)
FI (1) FI970959A (en)
HU (1) HUT77440A (en)
IS (1) IS4436A (en)
NO (1) NO971070L (en)
NZ (1) NZ294095A (en)
OA (1) OA10601A (en)
PL (1) PL319440A1 (en)
SK (1) SK29197A3 (en)
WO (1) WO1996007646A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912356A (en) * 1995-09-11 1999-06-15 Glaxo Wellcome Inc. Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
CA2280761A1 (en) 1997-02-13 1998-08-20 Stanley Dawes Chamberlain Benzimidazole derivatives
PL338454A1 (en) 1997-07-30 2000-11-06 Univ Michigan Lixofuranosilbenzimidazoles as antiviral agents
EP1162196A4 (en) 1999-12-27 2003-04-16 Japan Tobacco Inc Fused-ring compounds and use thereof as drugs
US6770666B2 (en) 1999-12-27 2004-08-03 Japan Tobacco Inc. Fused-ring compounds and use thereof as drugs
GB0008939D0 (en) 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
AR035543A1 (en) * 2001-06-26 2004-06-16 Japan Tobacco Inc THERAPEUTIC AGENT FOR HEPATITIS C THAT INCLUDES A CONDENSED RING COMPOUND, CONDENSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS, BENZIMIDAZOL, THIAZOL AND BIFENYL COMPOUNDS USED AS INTERMEDIARY COMPARTMENTS OF COMPARTMENTS
CN1834090B (en) * 2005-03-18 2011-06-29 中国科学院上海药物研究所 Benzimidazole compound, its preparation method and use
ES2758027T3 (en) 2007-08-02 2020-05-04 Millennium Pharm Inc Intermediates for the synthesis of E1 activity activating enzyme inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides

Also Published As

Publication number Publication date
CA2199502A1 (en) 1996-03-14
AP741A (en) 1999-04-26
NZ294095A (en) 1998-08-26
MX9701789A (en) 1997-10-31
HUT77440A (en) 1998-04-28
NO971070L (en) 1997-05-07
IS4436A (en) 1997-03-07
AP9700940A0 (en) 1997-04-30
PL319440A1 (en) 1997-08-04
CZ71297A3 (en) 1997-08-13
EP0779885A1 (en) 1997-06-25
AU3692895A (en) 1996-03-27
CN1164855A (en) 1997-11-12
FI970959A (en) 1997-05-06
BR9508826A (en) 1997-09-30
WO1996007646A1 (en) 1996-03-14
JPH10505092A (en) 1998-05-19
NO971070D0 (en) 1997-03-07
SK29197A3 (en) 1997-10-08
OA10601A (en) 2002-09-03

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