FI970918L - Föreningar och förfarande för behandling av cancer - Google Patents
Föreningar och förfarande för behandling av cancer Download PDFInfo
- Publication number
- FI970918L FI970918L FI970918A FI970918A FI970918L FI 970918 L FI970918 L FI 970918L FI 970918 A FI970918 A FI 970918A FI 970918 A FI970918 A FI 970918A FI 970918 L FI970918 L FI 970918L
- Authority
- FI
- Finland
- Prior art keywords
- compounds
- methods
- treating cancer
- cancer
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/301,298 US5817667A (en) | 1991-04-17 | 1994-09-06 | Compounds and methods for the treatment of cancer |
US39063395A | 1995-02-17 | 1995-02-17 | |
PCT/US1995/011464 WO1996007413A1 (en) | 1994-09-06 | 1995-09-05 | Compounds and methods for the treatment of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
FI970918A0 FI970918A0 (sv) | 1997-03-04 |
FI970918L true FI970918L (sv) | 1997-05-02 |
Family
ID=26972285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970918A FI970918L (sv) | 1994-09-06 | 1997-03-04 | Föreningar och förfarande för behandling av cancer |
Country Status (31)
Country | Link |
---|---|
US (3) | US6063787A (sv) |
EP (2) | EP1468687A1 (sv) |
JP (1) | JP3979662B2 (sv) |
KR (1) | KR100374477B1 (sv) |
CN (3) | CN1827108A (sv) |
AP (1) | AP783A (sv) |
AT (1) | ATE267015T1 (sv) |
AU (1) | AU704977B2 (sv) |
BG (1) | BG63122B1 (sv) |
BR (1) | BR9508886A (sv) |
CA (1) | CA2199117C (sv) |
CZ (1) | CZ297873B6 (sv) |
DE (1) | DE69533066T2 (sv) |
DK (1) | DK0781136T3 (sv) |
ES (1) | ES2219666T3 (sv) |
FI (1) | FI970918L (sv) |
HU (1) | HUT77172A (sv) |
IL (1) | IL115156A (sv) |
IS (1) | IS2011B (sv) |
MY (1) | MY121548A (sv) |
NO (1) | NO313268B1 (sv) |
NZ (1) | NZ335013A (sv) |
OA (1) | OA10473A (sv) |
PL (2) | PL188359B1 (sv) |
PT (1) | PT781136E (sv) |
RO (1) | RO118748B1 (sv) |
RU (1) | RU2168995C2 (sv) |
SI (1) | SI0781136T1 (sv) |
SK (1) | SK284564B6 (sv) |
WO (1) | WO1996007413A1 (sv) |
ZA (1) | ZA957483B (sv) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6903224B2 (en) | 1988-04-11 | 2005-06-07 | Biochem Pharma Inc. | Substituted 1,3-oxathiolanes |
US6069252A (en) | 1990-02-01 | 2000-05-30 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
US6022876A (en) * | 1996-11-15 | 2000-02-08 | Yale University | L-β-dioxolane uridine analogs and methods for treating and preventing Epstein-Barr virus infections |
AU9016998A (en) | 1997-08-08 | 1999-03-01 | Newbiotics, Inc. | Methods and compositions for overcoming resistance to biologic and chemotherapy |
US7462605B2 (en) | 1998-01-23 | 2008-12-09 | Celmed Oncology (Usa), Inc. | Phosphoramidate compounds and methods of use |
DE69900841T2 (de) | 1998-01-23 | 2002-10-02 | Newbiotics Inc., San Diego | Durch enzymkatalyse erhaltene therapeutische substanzen. |
JP2002504558A (ja) | 1998-02-25 | 2002-02-12 | エモリー ユニバーシテイ | 2’−フルオロヌクレオシド |
AU2004201676B2 (en) * | 1999-03-29 | 2006-03-09 | University Of Georgia Research Foundation, Inc. | Methods of treating leukemia |
HUP0201708A3 (en) * | 1999-03-29 | 2005-02-28 | Shire Biochem Inc Laval | The use of nucleoside analogues for treating leukemia |
US6653318B1 (en) | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US6683061B1 (en) | 1999-07-22 | 2004-01-27 | Newbiotics, Inc. | Enzyme catalyzed therapeutic activation |
ATE269081T1 (de) | 1999-09-24 | 2004-07-15 | Shire Biochem Inc | Dioxolan nukleosidanalogen zur behandlung und vorbeugung von viralen infektionen |
WO2001032153A2 (en) | 1999-11-04 | 2001-05-10 | Shire Biochem Inc. | Method for the treatment or prevention of flaviviridae viral infection using nucleoside analogues |
EP1634888A3 (en) | 1999-11-12 | 2007-11-21 | Pharmasset, Inc. | Synthesis of 2'-deoxy-L-nucleosides |
PL361310A1 (en) * | 2000-10-13 | 2004-10-04 | Shire Biochem Inc. | Dioxolane analogs for improved inter-cellular delivery |
US7138388B2 (en) | 2001-01-19 | 2006-11-21 | Celmed Oncology (Usa), Inc. | Methods to treat autoimmune and inflammatory conditions |
US6800639B2 (en) * | 2001-03-23 | 2004-10-05 | Shire Biochem Inc. | Pharmaceutical combination for the treatment of cancer |
CN1744902B (zh) * | 2001-03-23 | 2010-05-26 | 希拉加拿大股份有限公司 | 治疗癌症的药物组合 |
AU2002242561A1 (en) * | 2001-03-30 | 2002-10-15 | Shire Biochem Inc. | Methods of treating cancer using cyplastin combined with a dioxolane nucleoside such as troxacitabine |
US6645972B2 (en) | 2001-11-02 | 2003-11-11 | Shire Biochem Inc. | Methods of treating leukemia |
EP2055300B1 (de) * | 2001-11-19 | 2016-01-27 | Medigene AG | Arzneimittel enthaltend Isopropylmyristat und ein Catechin |
KR100631243B1 (ko) | 2002-06-21 | 2006-10-02 | 엘지전자 주식회사 | 비디오 데이터의 재생을 관리하기 위한 데이터 구조를갖는 기록 매체 |
CN1556988B (zh) | 2002-06-21 | 2011-09-14 | Lg电子株式会社 | 具有用于管理记录在其上面的视频数据的再现的数据结构的记录介质 |
KR20040000290A (ko) | 2002-06-24 | 2004-01-03 | 엘지전자 주식회사 | 고밀도 광디스크의 멀티 경로 데이터 스트림 관리방법 |
US7949231B2 (en) | 2002-06-24 | 2011-05-24 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of multiple reproduction path video data recorded thereon and recording and reproducing methods and apparatuses |
JP4312151B2 (ja) | 2002-06-28 | 2009-08-12 | エルジー エレクトロニクス インコーポレーテッド | 多重経路データの記録及び再生を管理するためのデータ構造を有する記録媒体と、それによって記録し、再生する方法及び装置 |
JP4431043B2 (ja) | 2002-10-14 | 2010-03-10 | エルジー エレクトロニクス インコーポレイティド | 記録された複数のオーディオストリームの再生を管理するためのデータ構造を有する光ディスク、それによる記録及び再生方法及び装置 |
WO2004036578A1 (en) | 2002-10-15 | 2004-04-29 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of multiple graphics streams recorded thereon and recording and reproducing methods and apparatuses |
US7720356B2 (en) | 2002-11-12 | 2010-05-18 | Lg Electronics Inc | Recording medium having data structure for managing reproduction of multiple reproduction path video data recorded thereon and recording and reproducing methods and apparatuses |
JP4242839B2 (ja) | 2002-11-12 | 2009-03-25 | エルジー エレクトロニクス インコーポレーテッド | 記録された多重再生経路ビデオデータの再生を管理するためのデータ構造を有する記録媒体とそれによる記録及び再生方法及び装置 |
US7664372B2 (en) | 2002-11-20 | 2010-02-16 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of multiple component data recorded thereon and recording and reproducing methods and apparatuses |
US7606463B2 (en) | 2003-02-24 | 2009-10-20 | Lg Electronics, Inc. | Recording medium having data structure for managing playback control and recording and reproducing methods and apparatuses |
US7693394B2 (en) | 2003-02-26 | 2010-04-06 | Lg Electronics Inc. | Recording medium having data structure for managing reproduction of data streams recorded thereon and recording and reproducing methods and apparatuses |
US7809775B2 (en) | 2003-02-27 | 2010-10-05 | Lg Electronics, Inc. | Recording medium having data structure for managing playback control recorded thereon and recording and reproducing methods and apparatuses |
CN100397882C (zh) | 2003-02-28 | 2008-06-25 | Lg电子株式会社 | 具有用于管理记录其上的视频数据的随机/洗牌重现的数据结构的记录媒体以及记录和重现的方法和装置 |
US7620301B2 (en) | 2003-04-04 | 2009-11-17 | Lg Electronics Inc. | System and method for resuming playback |
ES2391561T3 (es) | 2003-10-09 | 2012-11-27 | Medigene Ag | Uso de un polifenol para el tratamiento de una lesión cancerosa o pre-cancerosa de la piel |
WO2006133092A1 (en) | 2005-06-07 | 2006-12-14 | Yale University | Methods of treating cancer and other conditions or disease states using lfmau and ldt |
WO2007067364A2 (en) * | 2005-12-02 | 2007-06-14 | Yale University | Methods of treating cancer and other conditions or disease states using l-cytosine nucleoside analogs |
NO324263B1 (no) | 2005-12-08 | 2007-09-17 | Clavis Pharma Asa | Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser |
CN101534835B (zh) * | 2006-09-01 | 2012-05-30 | 佐治亚大学研究基金会 | 用于癌症的L-OddC的前药 |
CN103720693A (zh) * | 2011-11-15 | 2014-04-16 | 张始状 | 人体五种正常碱基在制备治疗肿瘤药物中的应用 |
CN102406649A (zh) * | 2011-11-15 | 2012-04-11 | 张始状 | 人体五种正常碱基在制备治疗肿瘤药物中的应用 |
SG10201609131YA (en) | 2016-11-01 | 2018-06-28 | Xylonix Ip Holdings Pte Ltd | Zinc-pga compositions and methods for treating cancer |
AU2017387549B2 (en) * | 2016-12-28 | 2023-07-06 | Transgene Sa | Oncolytic viruses and therapeutic molecules |
SG10201708886RA (en) * | 2017-10-30 | 2019-05-30 | Xylonix Ip Holdings Pte Ltd | α-PGA-ZINC COMPOSITIONS AND METHODS FOR TREATING CANCER |
Family Cites Families (52)
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US4000137A (en) * | 1975-06-10 | 1976-12-28 | American Home Products Corporation | Antitumor derivatives of periodate-oxidized nucleosides |
JPS5668674A (en) * | 1979-11-08 | 1981-06-09 | Shionogi & Co Ltd | 5-fluorouracil derivative |
GR861255B (en) * | 1985-05-15 | 1986-09-16 | Wellcome Found | Therapeutic nucleosides |
AU570853B2 (en) * | 1985-08-26 | 1988-03-24 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Inhibition of infectivity and cytopathic effect of htlv-111/ lav by purine bases |
US4879277A (en) * | 1985-08-26 | 1989-11-07 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral compositions and methods |
DE3650741T2 (de) * | 1985-09-17 | 2000-10-12 | The Wellcome Foundation Ltd., Greenford | Kombination therapeutische Nukleoside mit weiteren therapeutisch wirksamen Komponenten. |
IN164556B (sv) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
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NZ228645A (en) * | 1988-04-11 | 1991-09-25 | Iaf Biochem Int | 1,3-dioxolane derivatives substituted in the 5th position by a purine or pyrimidine radical; treatment of viral infections |
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US5041449A (en) * | 1988-04-11 | 1991-08-20 | Iaf Biochem International, Inc. | 4-(nucleoside base)-substituted-1,3-dioxolanes useful for treatment of retroviral infections |
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SE8802687D0 (sv) * | 1988-07-20 | 1988-07-20 | Astra Ab | Nucleoside derivatives |
EP0375329B1 (en) * | 1988-12-19 | 1995-05-31 | The Wellcome Foundation Limited | Antiviral pyrimidine and purine compounds, process for their preparation and pharmaceutical compositions containing them |
UA45942A (uk) * | 1989-02-08 | 2002-05-15 | Біокем Фарма, Інк. | 1,3-оксатіолан, його похідні, спосіб (варіанти) його одержання та фармацевтична композиція |
NZ233197A (en) * | 1989-04-13 | 1991-11-26 | Richard Thomas Walker | Aromatically substituted nucleotide derivatives, intermediates therefor and pharmaceutical compositions |
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IE904378A1 (en) * | 1989-12-20 | 1991-07-03 | Abbott Lab | Analogs of oxetanyl purines and pyrimidines |
US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
US5700937A (en) * | 1990-02-01 | 1997-12-23 | Emory University | Method for the synthesis, compositions and use of 2'-deoxy-5-fluoro-3'-thiacytidine and related compounds |
US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
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US5179104A (en) * | 1990-12-05 | 1993-01-12 | University Of Georgia Research Foundation, Inc. | Process for the preparation of enantiomerically pure β-D-(-)-dioxolane-nucleosides |
US5248776A (en) * | 1990-12-05 | 1993-09-28 | University Of Georgia Research Foundation, Inc. | Process for enantiomerically pure β-L-1,3-oxathiolane nucleosides |
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WO1992010496A1 (en) * | 1990-12-05 | 1992-06-25 | University Of Georgia Research Foundation, Inc. | ENANTIOMERICALLY PURE β-L-(-)-1,3-OXATHIOLANE NUCLEOSIDES |
IL100502A (en) * | 1991-01-03 | 1995-12-08 | Iaf Biochem Int | PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (- |
NZ241625A (en) * | 1991-02-22 | 1996-03-26 | Univ Emory | 1,3-oxathiolane derivatives, anti-viral compositions containing such and method of resolving racemic mixture of enantiomers |
CA2105486C (en) * | 1991-03-06 | 2003-10-28 | George Robert Painter Iii | Therapeutic nucleosides |
GB9104740D0 (en) * | 1991-03-06 | 1991-04-17 | Wellcome Found | Antiviral nucleoside combination |
US5817667A (en) * | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
WO1992018517A1 (en) * | 1991-04-17 | 1992-10-29 | Yale University | Method of treating or preventing hepatitis b virus |
GB9110874D0 (en) * | 1991-05-20 | 1991-07-10 | Iaf Biochem Int | Medicaments |
ZA923641B (en) * | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
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IL115156A (en) * | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
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-
1995
- 1995-09-04 IL IL11515695A patent/IL115156A/xx not_active IP Right Cessation
- 1995-09-05 EP EP04003357A patent/EP1468687A1/en not_active Withdrawn
- 1995-09-05 EP EP95933071A patent/EP0781136B1/en not_active Expired - Lifetime
- 1995-09-05 JP JP50970596A patent/JP3979662B2/ja not_active Expired - Lifetime
- 1995-09-05 RO RO97-00419A patent/RO118748B1/ro unknown
- 1995-09-05 BR BR9508886A patent/BR9508886A/pt not_active Application Discontinuation
- 1995-09-05 RU RU97105381/04A patent/RU2168995C2/ru not_active IP Right Cessation
- 1995-09-05 CA CA002199117A patent/CA2199117C/en not_active Expired - Fee Related
- 1995-09-05 PL PL95318971A patent/PL188359B1/pl not_active IP Right Cessation
- 1995-09-05 DE DE69533066T patent/DE69533066T2/de not_active Expired - Lifetime
- 1995-09-05 DK DK95933071T patent/DK0781136T3/da active
- 1995-09-05 ES ES95933071T patent/ES2219666T3/es not_active Expired - Lifetime
- 1995-09-05 SI SI9530703T patent/SI0781136T1/xx unknown
- 1995-09-05 CN CNA2006100549917A patent/CN1827108A/zh active Pending
- 1995-09-05 SK SK281-97A patent/SK284564B6/sk not_active IP Right Cessation
- 1995-09-05 KR KR1019970701464A patent/KR100374477B1/ko not_active Expired - Lifetime
- 1995-09-05 AU AU35862/95A patent/AU704977B2/en not_active Ceased
- 1995-09-05 AT AT95933071T patent/ATE267015T1/de not_active IP Right Cessation
- 1995-09-05 CZ CZ0063397A patent/CZ297873B6/cs not_active IP Right Cessation
- 1995-09-05 HU HU9701687A patent/HUT77172A/hu unknown
- 1995-09-05 AP APAP/P/1997/000939A patent/AP783A/en active
- 1995-09-05 PT PT95933071T patent/PT781136E/pt unknown
- 1995-09-05 WO PCT/US1995/011464 patent/WO1996007413A1/en active IP Right Grant
- 1995-09-05 US US08/809,007 patent/US6063787A/en not_active Expired - Fee Related
- 1995-09-05 CN CN95195621A patent/CN1111409C/zh not_active Expired - Lifetime
- 1995-09-05 PL PL95358979A patent/PL189288B1/pl not_active IP Right Cessation
- 1995-09-06 ZA ZA957483A patent/ZA957483B/xx unknown
- 1995-09-06 MY MYPI95002637A patent/MY121548A/en unknown
-
1997
- 1997-03-03 OA OA60972A patent/OA10473A/en unknown
- 1997-03-04 IS IS4434A patent/IS2011B/is unknown
- 1997-03-04 FI FI970918A patent/FI970918L/sv unknown
- 1997-03-05 NO NO19971015A patent/NO313268B1/no not_active IP Right Cessation
- 1997-03-05 BG BG101284A patent/BG63122B1/xx unknown
-
1999
- 1999-04-01 NZ NZ335013A patent/NZ335013A/xx not_active IP Right Cessation
-
2003
- 2003-04-18 CN CNB031106706A patent/CN1251680C/zh not_active Expired - Lifetime
- 2003-08-22 US US10/646,980 patent/US7262213B2/en not_active Expired - Lifetime
-
2007
- 2007-03-05 US US11/713,975 patent/US8076347B2/en not_active Expired - Lifetime
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