FI970113A0 - Helico-bakteerin vastaisia atsolonien sulfonamidijohdannaisia - Google Patents
Helico-bakteerin vastaisia atsolonien sulfonamidijohdannaisiaInfo
- Publication number
- FI970113A0 FI970113A0 FI970113A FI970113A FI970113A0 FI 970113 A0 FI970113 A0 FI 970113A0 FI 970113 A FI970113 A FI 970113A FI 970113 A FI970113 A FI 970113A FI 970113 A0 FI970113 A0 FI 970113A0
- Authority
- FI
- Finland
- Prior art keywords
- image
- 4alkyl
- compounds
- helicobacterial
- azolone
- Prior art date
Links
- -1 azolone sulfonamide Chemical class 0.000 title abstract 2
- 229940124530 sulfonamide Drugs 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000003830 C1- C4 alkylcarbonylamino group Chemical group 0.000 abstract 1
- 206010019375 Helicobacter infections Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004786 difluoromethoxy group Chemical group [H]C(F)(F)O* 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Lubricants (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94202015 | 1994-07-12 | ||
| PCT/EP1995/002619 WO1996001818A1 (en) | 1994-07-12 | 1995-07-05 | Sulfonamide derivatives of azolones anti-helicobacter agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI970113A0 true FI970113A0 (fi) | 1997-01-10 |
| FI970113A FI970113A (fi) | 1997-01-10 |
Family
ID=8217029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI970113A FI970113A (fi) | 1994-07-12 | 1997-01-10 | Helico-bakteerin vastaisia atsolonien sulfonamidijohdannaisia |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5571811A (fi) |
| EP (1) | EP0770071B1 (fi) |
| JP (1) | JPH10502386A (fi) |
| CN (1) | CN1068878C (fi) |
| AT (1) | ATE206706T1 (fi) |
| AU (1) | AU684981B2 (fi) |
| BR (1) | BR9508376A (fi) |
| CA (1) | CA2194562A1 (fi) |
| CZ (1) | CZ2997A3 (fi) |
| DE (1) | DE69523159T2 (fi) |
| FI (1) | FI970113A (fi) |
| HU (1) | HUT76636A (fi) |
| IL (1) | IL114537A (fi) |
| MX (1) | MX9700340A (fi) |
| NO (1) | NO970089L (fi) |
| NZ (1) | NZ289853A (fi) |
| PL (1) | PL318149A1 (fi) |
| SK (1) | SK4497A3 (fi) |
| TW (1) | TW341571B (fi) |
| WO (1) | WO1996001818A1 (fi) |
| ZA (1) | ZA955760B (fi) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5639754A (en) * | 1994-07-12 | 1997-06-17 | Janssen Pharmaceutica N.V. | Urea and thiourea derivatives of azolones |
| US5637592A (en) * | 1994-07-12 | 1997-06-10 | Janssen Pharmaceutica N.V. | Acyl derivatives of azolones |
| US5571811A (en) * | 1994-07-12 | 1996-11-05 | Janssen Pharmaceutica N.V. | Sulfonamide derivatives of azolones |
| KR100484328B1 (ko) | 1999-03-17 | 2005-04-20 | 모리나가 세이카 가부시키가이샤 | 코코아 성분을 함유하는 음식물 |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| US6780880B1 (en) * | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US20050119251A1 (en) * | 2001-12-21 | 2005-06-02 | Jian-Min Fu | Nicotinamide derivatives and their use as therapeutic agents |
| AU2003282244B2 (en) * | 2002-11-14 | 2008-11-20 | Aderans Research Institute, Inc. | Cultivation of hair inductive cells |
| AU2004221812B2 (en) * | 2003-03-19 | 2010-02-18 | Exelixis Inc. | Tie-2 modulators and methods of use |
| US7829712B2 (en) * | 2004-09-20 | 2010-11-09 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase |
| CN101084211A (zh) * | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为治疗剂的用途 |
| WO2006034441A1 (en) * | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
| WO2006034440A2 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
| CA2580860A1 (en) * | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Pyridine derivatives for inhibiting human stearoyl-coa-desaturase |
| AU2005286728A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase |
| TW200626139A (en) * | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| AR051294A1 (es) * | 2004-09-20 | 2007-01-03 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
| CN101083982A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物 |
| EP2029138A1 (en) * | 2005-06-03 | 2009-03-04 | Xenon Pharmaceuticals Inc. | Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors |
| US20220122691A1 (en) * | 2019-01-06 | 2022-04-21 | Psomagen Inc. | HtrA Inhibitors and CagA Inhibitors and Use Thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1292472C (en) * | 1985-12-03 | 1991-11-26 | Alfonsus Guilielmus Knaeps | Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles |
| US4791111A (en) * | 1985-12-23 | 1988-12-13 | Janssen Pharmaceutica, N.V. | [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties |
| CA1331757C (en) * | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
| CA2076257A1 (en) * | 1991-09-13 | 1993-03-14 | Jan Heeres | 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives |
| US5571811A (en) * | 1994-07-12 | 1996-11-05 | Janssen Pharmaceutica N.V. | Sulfonamide derivatives of azolones |
-
1995
- 1995-05-23 US US08/447,505 patent/US5571811A/en not_active Expired - Fee Related
- 1995-05-25 TW TW084105259A patent/TW341571B/zh active
- 1995-07-05 PL PL95318149A patent/PL318149A1/xx unknown
- 1995-07-05 BR BR9508376A patent/BR9508376A/pt unknown
- 1995-07-05 SK SK44-97A patent/SK4497A3/sk unknown
- 1995-07-05 AU AU29819/95A patent/AU684981B2/en not_active Ceased
- 1995-07-05 HU HU9700080A patent/HUT76636A/hu unknown
- 1995-07-05 CA CA002194562A patent/CA2194562A1/en not_active Abandoned
- 1995-07-05 CZ CZ9729A patent/CZ2997A3/cs unknown
- 1995-07-05 JP JP8504112A patent/JPH10502386A/ja active Pending
- 1995-07-05 EP EP95925838A patent/EP0770071B1/en not_active Expired - Lifetime
- 1995-07-05 MX MX9700340A patent/MX9700340A/es unknown
- 1995-07-05 CN CN95194022A patent/CN1068878C/zh not_active Expired - Fee Related
- 1995-07-05 DE DE69523159T patent/DE69523159T2/de not_active Expired - Fee Related
- 1995-07-05 WO PCT/EP1995/002619 patent/WO1996001818A1/en active IP Right Grant
- 1995-07-05 AT AT95925838T patent/ATE206706T1/de not_active IP Right Cessation
- 1995-07-05 US US08/776,003 patent/US5728700A/en not_active Expired - Fee Related
- 1995-07-11 ZA ZA955760A patent/ZA955760B/xx unknown
- 1995-07-11 IL IL11453795A patent/IL114537A/xx active IP Right Grant
-
1997
- 1997-01-08 NZ NZ289853A patent/NZ289853A/en unknown
- 1997-01-09 NO NO970089A patent/NO970089L/no not_active Application Discontinuation
- 1997-01-10 FI FI970113A patent/FI970113A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE206706T1 (de) | 2001-10-15 |
| PL318149A1 (en) | 1997-05-12 |
| HUT76636A (en) | 1997-10-28 |
| SK4497A3 (en) | 1997-12-10 |
| JPH10502386A (ja) | 1998-03-03 |
| NO970089L (no) | 1997-03-10 |
| CA2194562A1 (en) | 1996-01-25 |
| EP0770071A1 (en) | 1997-05-02 |
| DE69523159D1 (de) | 2001-11-15 |
| TW341571B (en) | 1998-10-01 |
| BR9508376A (pt) | 1997-10-28 |
| ZA955760B (en) | 1997-01-13 |
| MX9700340A (es) | 1997-05-31 |
| NO970089D0 (no) | 1997-01-09 |
| CN1068878C (zh) | 2001-07-25 |
| EP0770071B1 (en) | 2001-10-10 |
| DE69523159T2 (de) | 2002-06-20 |
| US5728700A (en) | 1998-03-17 |
| AU2981995A (en) | 1996-02-09 |
| CN1152308A (zh) | 1997-06-18 |
| US5571811A (en) | 1996-11-05 |
| WO1996001818A1 (en) | 1996-01-25 |
| CZ2997A3 (en) | 1997-09-17 |
| AU684981B2 (en) | 1998-01-08 |
| FI970113A (fi) | 1997-01-10 |
| HU9700080D0 (en) | 1997-02-28 |
| IL114537A (en) | 1999-04-11 |
| IL114537A0 (en) | 1995-11-27 |
| NZ289853A (en) | 1997-11-24 |
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