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FI96872B - Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen - Google Patents

Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen

Info

Publication number
FI96872B
FI96872B FI885807A FI885807A FI96872B FI 96872 B FI96872 B FI 96872B FI 885807 A FI885807 A FI 885807A FI 885807 A FI885807 A FI 885807A FI 96872 B FI96872 B FI 96872B
Authority
FI
Finland
Prior art keywords
biologically active
human csf
purified
production
recombinant human
Prior art date
Application number
FI885807A
Other languages
English (en)
Swedish (sv)
Other versions
FI885807L (fi
FI96872C (fi
FI885807A0 (fi
Inventor
Robert F Halenbeck
Kirston E Koths
Cynthia Cowgill
Walter J Laird
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of FI885807L publication Critical patent/FI885807L/fi
Publication of FI885807A0 publication Critical patent/FI885807A0/fi
Publication of FI96872B publication Critical patent/FI96872B/fi
Application granted granted Critical
Publication of FI96872C publication Critical patent/FI96872C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI885807A 1987-04-16 1988-12-15 Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen FI96872C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US4017487A 1987-04-16 1987-04-16
US4017487 1987-04-16
US11400187A 1987-10-27 1987-10-27
US11400187 1987-10-27
PCT/US1988/001189 WO1988008003A1 (en) 1987-04-16 1988-04-18 Production of purified, biologically active, bacterially produced recombinant human csf-1
US8801189 1988-04-18

Publications (4)

Publication Number Publication Date
FI885807L FI885807L (fi) 1988-12-15
FI885807A0 FI885807A0 (fi) 1988-12-15
FI96872B true FI96872B (fi) 1996-05-31
FI96872C FI96872C (fi) 1996-09-10

Family

ID=26716797

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885807A FI96872C (fi) 1987-04-16 1988-12-15 Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen

Country Status (10)

Country Link
EP (2) EP0818466B1 (fi)
JP (1) JP2656964B2 (fi)
AT (2) ATE301133T1 (fi)
AU (1) AU610182B2 (fi)
BG (1) BG49827A3 (fi)
DE (2) DE3856581T2 (fi)
FI (1) FI96872C (fi)
IL (1) IL86090A (fi)
NO (1) NO300067B1 (fi)
WO (1) WO1988008003A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
WO1989010407A1 (en) * 1988-04-29 1989-11-02 Genetics Institute, Inc. Homogeneous dimeric m-csf and storage stable formulations thereof
DE69026440T2 (de) * 1989-07-27 1996-10-17 Denki Kagaku Kogyo Kk Für M-CSF kodierendes Gen und dazu gehörende rekombinante Systeme
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
AU8417091A (en) * 1990-08-20 1992-03-17 Novo Nordisk A/S Biologically active compound, a process for the preparation thereof and use of the same
DK0547102T3 (da) * 1990-09-05 1999-04-19 Natinco Nv Opløseliggørelse af proteiner på aktiv form
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
CA2137793C (en) 1992-06-09 2003-04-22 Jayvardhan Pandit Crystallization of m-csf
AU661914B2 (en) * 1992-08-18 1995-08-10 Jean-Louis Odore Support structure for a shelter cover
SG49862A1 (en) * 1993-08-04 2002-03-19 Ucp Gen Pharma Ag High molecular weight desulphatohirudin
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
TW517059B (en) 1994-07-25 2003-01-11 Ciba Geigy Ag New process for the production of biologically active protein
FR2796071B1 (fr) * 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes
US6808902B1 (en) * 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
DE102004041639A1 (de) * 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
JP5808323B2 (ja) 2009-06-22 2015-11-10 アムジエン・インコーポレーテツド 化学的に制御されたレドックス状態を用いたタンパク質のリフォールディング
EP3660032A1 (en) 2009-06-25 2020-06-03 Amgen, Inc Capture purification processes for proteins expressed in a non-mammalian system
DE202009019091U1 (de) 2009-12-21 2016-05-23 Agilent Technologies, Inc. - A Delaware Corporation - Fittingelement mit frontseitiger Einlage

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (fi) * 1982-12-22 1984-10-02 Genentech Inc
EP0209601B1 (en) * 1985-02-05 1993-12-15 Cetus Oncology Corporation Recombinant colony stimulating factor-1
WO1987006954A1 (en) * 1986-05-06 1987-11-19 Genetics Institute, Inc. Production of m-csf
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer

Also Published As

Publication number Publication date
DE3856581D1 (de) 2005-09-29
EP0309569B1 (en) 1998-06-10
EP0818466B1 (en) 2005-08-03
IL86090A0 (en) 1988-09-30
BG49827A3 (bg) 1992-02-14
IL86090A (en) 1993-03-15
AU1712488A (en) 1988-11-04
AU610182B2 (en) 1991-05-16
NO300067B1 (no) 1997-04-01
EP0309569A1 (en) 1989-04-05
NO885555L (no) 1989-01-11
WO1988008003A1 (en) 1988-10-20
NO885555D0 (no) 1988-12-14
JPH01503440A (ja) 1989-11-22
FI885807L (fi) 1988-12-15
DE3856203D1 (de) 1998-07-16
EP0818466A3 (en) 1998-03-25
FI96872C (fi) 1996-09-10
FI885807A0 (fi) 1988-12-15
EP0818466A2 (en) 1998-01-14
ATE167192T1 (de) 1998-06-15
DE3856203T2 (de) 1998-10-08
ATE301133T1 (de) 2005-08-15
DE3856581T2 (de) 2006-05-24
JP2656964B2 (ja) 1997-09-24

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Legal Events

Date Code Title Description
BB Publication of examined application
GB Transfer or assigment of application

Owner name: CHIRON CORPORATION

FG Patent granted

Owner name: CHIRON CORPORATION

PC Transfer of assignment of patent

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC.

Free format text: NOVARTIS VACCINES AND DIAGNOSTICS, INC.

MA Patent expired