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FI964610A - Allyyliryhmiä sisältävien steroidien hapetus - Google Patents

Allyyliryhmiä sisältävien steroidien hapetus Download PDF

Info

Publication number
FI964610A
FI964610A FI964610A FI964610A FI964610A FI 964610 A FI964610 A FI 964610A FI 964610 A FI964610 A FI 964610A FI 964610 A FI964610 A FI 964610A FI 964610 A FI964610 A FI 964610A
Authority
FI
Finland
Prior art keywords
allyl
oxidation
allylic
delta
alkenes
Prior art date
Application number
FI964610A
Other languages
English (en)
Swedish (sv)
Other versions
FI964610A0 (fi
Inventor
Ross A Miller
Andrew S Thompson
Raman K Bakshi
Edward G Corley
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI964610A publication Critical patent/FI964610A/fi
Publication of FI964610A0 publication Critical patent/FI964610A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/46—Ruthenium, rhodium, osmium or iridium
    • B01J23/462—Ruthenium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/54—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
    • B01J23/56—Platinum group metals
    • B01J23/64—Platinum group metals with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
    • B01J23/652—Chromium, molybdenum or tungsten
    • B01J23/6527—Tungsten
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI964610A 1994-05-19 1996-11-18 Allyyliryhmiä sisältävien steroidien hapetus FI964610A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24593594A 1994-05-19 1994-05-19
PCT/US1995/006004 WO1995032215A1 (en) 1994-05-19 1995-05-15 Oxidation of steroids having allylic groups

Publications (2)

Publication Number Publication Date
FI964610A true FI964610A (fi) 1996-11-18
FI964610A0 FI964610A0 (fi) 1996-11-18

Family

ID=22928693

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964610A FI964610A0 (fi) 1994-05-19 1996-11-18 Allyyliryhmiä sisältävien steroidien hapetus

Country Status (23)

Country Link
US (1) US6369247B1 (fi)
EP (1) EP0759929B1 (fi)
JP (1) JPH10500682A (fi)
KR (1) KR970703359A (fi)
CN (1) CN1152316A (fi)
AT (1) ATE195741T1 (fi)
AU (1) AU688513B2 (fi)
BR (1) BR9507663A (fi)
CA (1) CA2190500A1 (fi)
CZ (1) CZ338896A3 (fi)
DE (1) DE69518515T2 (fi)
DK (1) DK0759929T3 (fi)
ES (1) ES2149365T3 (fi)
FI (1) FI964610A0 (fi)
GR (1) GR3034201T3 (fi)
HK (1) HK1009274A1 (fi)
HU (1) HU223613B1 (fi)
NZ (1) NZ287230A (fi)
PT (1) PT759929E (fi)
RO (1) RO116550B1 (fi)
RU (1) RU2149875C1 (fi)
SK (1) SK282278B6 (fi)
WO (1) WO1995032215A1 (fi)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763361A (en) * 1995-10-23 1998-06-09 Merck & Co., Inc. 17-alkyl-7-substituted-4-aza steroid derivatives as 5-α-reductase inhibitors
ES2160842T3 (es) * 1995-10-23 2001-11-16 Merck & Co Inc Derivados de esteroides 17-alquil-4-aza-7-sustituidos.
US5872126A (en) * 1996-09-06 1999-02-16 Merck & Co., Inc. Methods and compositions for treating preterm labor
US6686486B1 (en) 1997-05-07 2004-02-03 Padma Marwah Process for effecting allylic oxidation
US5869709A (en) * 1997-05-07 1999-02-09 Humanetics Corporation Process for effecting allylic oxidation
US6252119B1 (en) * 1997-07-28 2001-06-26 Salvador Jorge Antonio Riberiro Copper-catalysed allylic oxidation using alkyl hydroperoxide
US6187925B1 (en) 1997-12-23 2001-02-13 Merck & Co., Inc. Intermediates and process for the synthesis of azasteroids
US6384251B1 (en) 1998-03-18 2002-05-07 Humanetics Corporation Process for effecting allylic oxidation using dicarboxylic acid imides and chromium reagents
MXPA01011070A (es) 1999-04-30 2003-06-30 Arch Dev Corp Derivados de esteroides.
GB0020286D0 (en) * 2000-08-18 2000-10-04 Univ York Cobalt catalysed allylic oxidation of unsaturated steroids using alkyl hydroperoxide
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
DK1392713T3 (da) * 2001-05-03 2008-02-18 Univ Chicago Lever-X-receptoragonister
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
CA2482195A1 (en) * 2002-04-12 2003-10-23 The University Of Chicago Farnesoid x-activated receptor agonists
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
MX2007010881A (es) * 2005-03-10 2007-12-05 Jr Chem Llc Composiciones de peroxido de benzoilo y metodos de uso.
KR101352187B1 (ko) 2005-03-10 2014-02-17 제이알 켐, 엘엘씨 안정한 유기 퍼옥사이드 조성물
US20090306023A1 (en) * 2005-06-29 2009-12-10 Ramirez Jose E Stable organic peroxide compositions
US20070044810A1 (en) * 2005-06-29 2007-03-01 Jr Chem, Llc Method of enhanced drug application
US20070001145A1 (en) * 2005-06-29 2007-01-04 Faryniarz Joseph R Stable organic peroxide compositions
US7556820B2 (en) 2005-06-29 2009-07-07 Jr Chem, Llc Stable organic peroxide compositions
CN101619089B (zh) * 2009-07-28 2011-07-20 陈大刚 抗肿瘤药物cl168、其合成方法及应用
US8829213B2 (en) * 2009-07-29 2014-09-09 The University Of Chicago Liver X receptor agonists
KR101554402B1 (ko) * 2011-01-31 2015-09-18 아사히 가세이 케미칼즈 가부시키가이샤 혼합액 제조 장치 및 혼합액 조제 방법
US9828326B2 (en) 2011-12-27 2017-11-28 Northeast Ohio Medical University Amooranin compounds and analogs thereof and related methods of use
BR112015022794A2 (pt) * 2013-03-15 2019-11-19 Prevacus Inc síntese de ent-progesterona e intermediários da mesma
CN103788163B (zh) * 2014-01-27 2015-11-18 浙江大学 7-酮基甾类化合物的制备方法
US10730821B2 (en) 2015-11-23 2020-08-04 Retrotope, Inc. Site-specific isotopic labeling of 1,4-diene systems
CN106008423B (zh) * 2016-06-24 2018-02-02 云南民族大学 一种苯丙素类化合物及其制备方法和应用
WO2021168311A1 (en) 2020-02-21 2021-08-26 Retrotope, Inc. Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422443D0 (en) * 1984-09-05 1984-10-10 British Petroleum Co Plc Oxidation of hydrocarbons
DK173704B1 (da) 1985-04-17 2001-07-09 Hoffmann La Roche Fremgangsmåde til katalytisk oxidation af allyliske grupper
CZ283894A3 (en) * 1992-05-20 1995-09-13 Merck & Co Inc 7beta-substituted 4-aza-5alpha-cholestanones, their use for the preparation of pharmaceutical preparations and pharmaceutical compositions containing thereof
IL111467A0 (en) 1993-11-12 1994-12-29 Merck & Co Inc Pharmaceutical compositions comprising 7 beta -substituted -4-aza 5 alpha -cholestan-3-ones and 5 alpha reductase 1 inhibitors

Also Published As

Publication number Publication date
WO1995032215A1 (en) 1995-11-30
AU688513B2 (en) 1998-03-12
HK1009274A1 (en) 1999-05-28
ES2149365T3 (es) 2000-11-01
KR970703359A (ko) 1997-07-03
EP0759929B1 (en) 2000-08-23
DK0759929T3 (da) 2000-11-13
SK147896A3 (en) 1997-08-06
RO116550B1 (ro) 2001-03-30
PT759929E (pt) 2001-01-31
AU2588595A (en) 1995-12-18
HUT75778A (en) 1997-05-28
DE69518515T2 (de) 2001-04-19
GR3034201T3 (en) 2000-11-30
DE69518515D1 (de) 2000-09-28
HU9603187D0 (en) 1997-01-28
HU223613B1 (hu) 2004-10-28
FI964610A0 (fi) 1996-11-18
CN1152316A (zh) 1997-06-18
US6369247B1 (en) 2002-04-09
EP0759929A4 (en) 1998-09-30
EP0759929A1 (en) 1997-03-05
BR9507663A (pt) 1997-10-07
NZ287230A (en) 1997-07-27
CA2190500A1 (en) 1995-11-30
CZ338896A3 (en) 1997-07-16
ATE195741T1 (de) 2000-09-15
SK282278B6 (sk) 2002-01-07
JPH10500682A (ja) 1998-01-20
RU2149875C1 (ru) 2000-05-27

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