FI962319A - C5a receptor antagonists without significant agonist activity - Google Patents

C5a receptor antagonists without significant agonist activity Download PDF

Info

Publication number: FI962319A
Authority: FI; Finland
Prior art keywords: receptor antagonists; agonist activity; significant agonist; significant; activity
Prior art date: 1993-12-06

Application number

FI962319A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI962319A0 (en

Inventor

Oostrum Jan Van

William C Boyar

Nicholas G Galakatos

Jane V Peppard

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-06

Filing date

1996-06-03

Publication date

1996-06-03

1996-06-03 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1996-06-03 Publication of FI962319A publication Critical patent/FI962319A/en

1996-06-03 Publication of FI962319A0 publication Critical patent/FI962319A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Physical Education & Sports Medicine (AREA)

FI962319A 1993-12-06 1996-06-03 C5a receptor antagonists with no substantial agonist activity FI962319A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16259193A	1993-12-06	1993-12-06
PCT/IB1994/000359 WO1995016033A1 (en)	1993-12-06	1994-11-16	C5a RECEPTOR ANTAGONISTS HAVING SUBSTANTIALLY NO AGONIST ACTIVITY

Publications (2)

Publication Number	Publication Date
FI962319A true FI962319A (en)	1996-06-03
FI962319A0 FI962319A0 (en)	1996-06-03

Family

ID=22586301

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI962319A FI962319A0 (en)	1993-12-06	1996-06-03	C5a receptor antagonists with no substantial agonist activity

Country Status (15)

Country	Link
EP (1)	EP0733107A1 (en)
JP (1)	JPH09506258A (en)
CN (1)	CN1142854A (en)
AU (1)	AU698919B2 (en)
BR (1)	BR9408265A (en)
CA (1)	CA2176825A1 (en)
FI (1)	FI962319A0 (en)
HU (1)	HUT75990A (en)
IL (1)	IL111792A0 (en)
MX (1)	MXPA99008669A (en)
NO (1)	NO962348L (en)
NZ (1)	NZ274917A (en)
TW (1)	TW429262B (en)
WO (1)	WO1995016033A1 (en)
ZA (1)	ZA949647B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5837499A (en) *	1993-12-06	1998-11-17	Ciba-Geigy Corporation	DNA encoding C5A receptor antagonists having substantially no agonist activity and methods of expressing same
AU6125096A (en) *	1995-06-05	1996-12-24	Novartis Ag	C5a receptor antagonists having substantially no agonist activity and methods for preparation
WO1997022216A1 (en) *	1995-12-13	1997-06-19	Northern Telecom Limited	Integrated cellular voice and digital packet data telecommunications systems and methods for their operation
AUPO755097A0 (en)	1997-06-25	1997-07-17	University Of Queensland, The	Receptor agonist and antagonist
TWI767415B (en) *	2020-11-18	2022-06-11	中國醫藥大學	Automatic blood analysis system and automatic blood analysis method
CN113150106B (en) *	2021-04-26	2022-08-16	华中农业大学	Antibacterial peptide derived from complement component C5a and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0305615A1 (en) *	1987-09-03	1989-03-08	Immunetech Pharmaceuticals, Inc.	Peptide antagonists for the C5a anaphylatoxin
ES2054667T3 (en) *	1986-04-28	1994-08-16	Cetus Oncology Corp	MONOCLONAL ANTIBODIES AGAINST C5A AND DES-ARG74-C5A, THEIR PRODUCTION AND USE.

1994
- 1994-11-16 AU AU80025/94A patent/AU698919B2/en not_active Ceased
- 1994-11-16 CN CN94194914A patent/CN1142854A/en active Pending
- 1994-11-16 NZ NZ274917A patent/NZ274917A/en unknown
- 1994-11-16 JP JP7516068A patent/JPH09506258A/en active Pending
- 1994-11-16 BR BR9408265A patent/BR9408265A/en not_active Application Discontinuation
- 1994-11-16 CA CA002176825A patent/CA2176825A1/en not_active Abandoned
- 1994-11-16 WO PCT/IB1994/000359 patent/WO1995016033A1/en not_active Application Discontinuation
- 1994-11-16 EP EP94931155A patent/EP0733107A1/en not_active Withdrawn
- 1994-11-16 HU HU9601538A patent/HUT75990A/en unknown
- 1994-11-28 IL IL11179294A patent/IL111792A0/en unknown
- 1994-12-05 ZA ZA949647A patent/ZA949647B/en unknown
- 1994-12-13 TW TW083111578A patent/TW429262B/en not_active IP Right Cessation
1996
- 1996-06-03 FI FI962319A patent/FI962319A0/en unknown
- 1996-06-05 NO NO962348A patent/NO962348L/en not_active Application Discontinuation
1999
- 1999-09-21 MX MXPA99008669A patent/MXPA99008669A/en unknown

Also Published As

Publication number	Publication date
TW429262B (en)	2001-04-11
HUT75990A (en)	1997-05-28
AU8002594A (en)	1995-06-27
CN1142854A (en)	1997-02-12
MXPA99008669A (en)	2004-09-01
IL111792A0 (en)	1995-01-24
CA2176825A1 (en)	1995-06-15
AU698919B2 (en)	1998-11-12
EP0733107A1 (en)	1996-09-25
HU9601538D0 (en)	1996-07-29
WO1995016033A1 (en)	1995-06-15
NO962348L (en)	1996-08-05
ZA949647B (en)	1995-06-06
NZ274917A (en)	1998-03-25
BR9408265A (en)	1996-12-10
JPH09506258A (en)	1997-06-24
FI962319A0 (en)	1996-06-03
NO962348D0 (en)	1996-06-05

Publication	Publication Date	Title
NO965608D0 (en)	1996-12-27	Vitronectin receptor antagonists
NO983001D0 (en)	1998-06-26	Vitronectin receptor antagonists
NO983003D0 (en)	1998-06-26	Vitronectin receptor antagonists
DK0957917T3 (en)	2006-04-18	vitronectin receptor antagonists
NO983002D0 (en)	1998-06-26	Vitronectin receptor antagonists
NO972016D0 (en)	1997-04-30	Indolyl-Y receptor antagonists
ZA955391B (en)	1996-02-09	Vitronectin receptor antagonists
NO993350D0 (en)	1999-07-07	Vitronectin receptor antagonists
NO950606D0 (en)	1995-02-17	Adhesion receptor antagonists
ID24726A (en)	2000-08-03	TROMBIN RECEPTOR ANTAGONISTS
NO20001514D0 (en)	2000-03-23	Vitronectin receptor antagonist
NO20001407D0 (en)	2000-03-17	Vitronectin receptor antagonists
DK0906294T3 (en)	2003-05-05	Benzoxazinone-dopamine D4 receptor antagonists
DZ2322A1 (en)	2002-12-28	Vitronectin receptor antagonists.
FI962319A (en)	1996-06-03	C5a receptor antagonists without significant agonist activity
NO179550C (en)	1996-10-30	Tachykinin receptor antagonists
DE59503324D1 (en)	1998-10-01	Adhesion receptor antagonists
DK0660832T3 (en)	1998-09-14	Serotonin Receptor agents
SI0957917T1 (en)	2006-04-30	Vitronectin receptor antagonists

Legal Events

Date	Code	Title	Description
1997-08-11	GB	Transfer or assigment of application	Owner name: NOVARTIS AG