FI960253L - Stabilization of aerosolized proteins - Google Patents

Stabilization of aerosolized proteins Download PDF

Info

Publication number: FI960253L
Authority: FI; Finland
Prior art keywords: stabilization; aerosolized; proteins; aerosolized proteins
Prior art date: 1993-07-19

Application number

FI960253A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI960253A0 (en

Inventor

Tsutomu Arakawa

Ralph W Niven

Steven J Prestrelski

Original Assignee

Amgen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-19

Filing date

1996-01-18

Publication date

1996-03-18

1996-01-18 Application filed by Amgen Inc filed Critical Amgen Inc

1996-01-18 Publication of FI960253A0 publication Critical patent/FI960253A0/en

1996-03-18 Publication of FI960253L publication Critical patent/FI960253L/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Pulmonology (AREA)
Otolaryngology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Anesthesiology (AREA)
Toxicology (AREA)
Dispersion Chemistry (AREA)
Hematology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Colloid Chemistry (AREA)

FI960253A 1993-07-19 1996-01-18 Stabilization of aerosolized proteins FI960253L (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9384093A	1993-07-19	1993-07-19
PCT/US1994/008136 WO1995003034A1 (en)	1993-07-19	1994-07-19	Stabilization of aerosolized proteins

Publications (2)

Publication Number	Publication Date
FI960253A0 FI960253A0 (en)	1996-01-18
FI960253L true FI960253L (en)	1996-03-18

Family

ID=22241106

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI960253A FI960253L (en)	1993-07-19	1996-01-18	Stabilization of aerosolized proteins

Country Status (8)

Country	Link
EP (1)	EP0710102A1 (en)
JP (1)	JPH09501418A (en)
AU (1)	AU691514B2 (en)
CA (1)	CA2167538A1 (en)
FI (1)	FI960253L (en)
NO (1)	NO960217L (en)
NZ (1)	NZ271181A (en)
WO (1)	WO1995003034A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030113271A1 (en) *	1997-01-29	2003-06-19	University Technology Corporation	Formulations for pulmonary delivery
DE19733651A1 (en) *	1997-08-04	1999-02-18	Boehringer Ingelheim Pharma	Aqueous aerosol preparations containing biologically active marrow molecules and processes for producing corresponding aerosols
PL356641A1 (en) *	1999-12-30	2004-06-28	Chiron Corporation	Methods for pulmonary delivery of interleukin-2
TR200401573T4 (en)	2000-02-29	2004-08-23	Pfizer Products Inc.	Stabilized granulocyte colony stimulating factor
DE60219961T8 (en)	2001-02-02	2008-04-17	Ortho-Mcneil Pharmaceutical, Inc.	TREATMENT OF NEUROLOGICAL FUNCTIONAL DISORDERS WITH FRUCTOPYRANOSESULFAMATE AND ERYTHROPOETIN
US20030072717A1 (en)	2001-02-23	2003-04-17	Vapotronics, Inc.	Inhalation device having an optimized air flow path
EP1389137B1 (en) *	2001-05-21	2006-07-19	InJet Digital Aerosols Limited	Compositions for protein delivery via the pulmonary route
JP2004087560A (en)	2002-08-23	2004-03-18	Sansha Electric Mfg Co Ltd	Power supply apparatus
WO2009074634A2 (en) *	2007-12-13	2009-06-18	Glaxo Group Limited	Compositions for pulmonary delivery
EP2077132A1 (en)	2008-01-02	2009-07-08	Boehringer Ingelheim Pharma GmbH & Co. KG	Dispensing device, storage device and method for dispensing a formulation
WO2010112358A2 (en)	2009-03-31	2010-10-07	Boehringer Ingelheim International Gmbh	Method for coating a surface of a component
WO2010133294A2 (en)	2009-05-18	2010-11-25	Boehringer Ingelheim International Gmbh	Adapter, inhalation device, and atomizer
US10016568B2 (en)	2009-11-25	2018-07-10	Boehringer Ingelheim International Gmbh	Nebulizer
JP5715640B2 (en)	2009-11-25	2015-05-13	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Nebulizer
JP5658268B2 (en)	2009-11-25	2015-01-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Nebulizer
JP5874724B2 (en)	2010-06-24	2016-03-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Nebulizer
EP2694220B1 (en)	2011-04-01	2020-05-06	Boehringer Ingelheim International GmbH	Medical device comprising a container
US9827384B2 (en)	2011-05-23	2017-11-28	Boehringer Ingelheim International Gmbh	Nebulizer
BR112014002593B1 (en)	2011-08-02	2022-11-29	Alfasigma S.p.A	PHARMACEUTICAL COMPOSITION OF OXIDIZED AVIDIN SUITABLE FOR INHALATION AND RELATED KITS
WO2013152894A1 (en)	2012-04-13	2013-10-17	Boehringer Ingelheim International Gmbh	Atomiser with coding means
ES2836977T3 (en)	2013-08-09	2021-06-28	Boehringer Ingelheim Int	Nebulizer
EP3030298B1 (en)	2013-08-09	2017-10-11	Boehringer Ingelheim International GmbH	Nebulizer
EP3139984B1 (en)	2014-05-07	2021-04-28	Boehringer Ingelheim International GmbH	Nebulizer
NZ724724A (en)	2014-05-07	2022-01-28	Boehringer Ingelheim Int	Container, indicator device, and nebulizer
IL247927B (en)	2014-05-07	2022-09-01	Boehringer Ingelheim Int	Container, a device that turns a liquid into a fine spray and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4897256A (en) *	1986-11-25	1990-01-30	Abbott Laboratories	LHRH analog formulations
GB8921222D0 (en) *	1989-09-20	1989-11-08	Riker Laboratories Inc	Medicinal aerosol formulations
RU2054180C1 (en) *	1991-08-21	1996-02-10	Жирнов Олег Петрович (н/п)	Method and aerosol for treating respiratory virus infections

1994
- 1994-07-19 CA CA002167538A patent/CA2167538A1/en not_active Abandoned
- 1994-07-19 EP EP94924473A patent/EP0710102A1/en not_active Withdrawn
- 1994-07-19 NZ NZ271181A patent/NZ271181A/en unknown
- 1994-07-19 WO PCT/US1994/008136 patent/WO1995003034A1/en not_active Application Discontinuation
- 1994-07-19 JP JP7505271A patent/JPH09501418A/en active Pending
- 1994-07-19 AU AU74732/94A patent/AU691514B2/en not_active Ceased
1996
- 1996-01-18 FI FI960253A patent/FI960253L/en unknown
- 1996-01-18 NO NO960217A patent/NO960217L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
FI960253A0 (en)	1996-01-18
JPH09501418A (en)	1997-02-10
AU7473294A (en)	1995-02-20
NO960217L (en)	1996-03-18
CA2167538A1 (en)	1995-02-02
EP0710102A1 (en)	1996-05-08
WO1995003034A1 (en)	1995-02-02
AU691514B2 (en)	1998-05-21
NZ271181A (en)	1998-06-26
NO960217D0 (en)	1996-01-18

Publication	Publication Date	Title
FI960253L (en)	1996-03-18	Stabilization of aerosolized proteins
DE69422575D1 (en)	2000-02-17	System for the explanation of exhibits
PT1066828E (en)	2003-10-31	COMPOSITION OF AEROSOL
DE69418220D1 (en)	1999-06-10	Attachment of biomolecules
DE69434520D1 (en)	2005-12-01	BIOTINYLATION OF PROTEINS
DK91192D0 (en)	1992-07-10	PROTEIN
BR9403948A (en)	1995-06-13	Composition of matter
BR9403946A (en)	1995-06-13	Composition of matter
FI963613L (en)	1997-03-16	Stabilization of polyolefins
FI954541L (en)	1995-11-23	Therapeutic uses of keratinocyte growth factor
FI952574L (en)	1995-05-26	Glycosyltransferase-active proteins
DK132892D0 (en)	1992-10-30	PROTEINS
KR960016892A (en)	1996-06-17	Nephrotoxic alleviators of pharmaceuticals
DE69426333D1 (en)	2000-12-28	IMPROVEMENTS OF ANTIBACTERIAL COMPOSITIONS
DK75393D0 (en)	1993-06-24	PRODUCTION OF PROTEIN
NO931399D0 (en)	1993-04-16	USE OF NATURSTEIN
KR950003500U (en)	1995-02-16	Separate freezer of freezer
DE69404145D1 (en)	1997-08-14	COMPOSITIONS OF SUBSTANCES
EP0562624A3 (en)	1994-10-05	Stabilization of functional proteins
NO952904D0 (en)	1995-07-21	Lysine salt of 6-chloro-5-fluoro-3- (2-tenoyl) -2-oxindole-1-carboxamide
DK36193D0 (en)	1993-03-26	COURSE OF ACTION
DE69417915D1 (en)	1999-05-20	PURIFICATION OF URANHEXAFLUORID
KR950013629U (en)	1995-06-15	De-energizer of De-energizer
FI924835L (en)	1994-04-24	Protein fragments of Pectinatus bacteria
KR930026760U (en)	1993-12-28	Improved configuration of TVCR