FI951514A - Uusia mono- ja bisyklisiä DNA-gyraasiinhibiittoreita - Google Patents
Uusia mono- ja bisyklisiä DNA-gyraasiinhibiittoreita Download PDFInfo
- Publication number
- FI951514A FI951514A FI951514A FI951514A FI951514A FI 951514 A FI951514 A FI 951514A FI 951514 A FI951514 A FI 951514A FI 951514 A FI951514 A FI 951514A FI 951514 A FI951514 A FI 951514A
- Authority
- FI
- Finland
- Prior art keywords
- dna gyrase
- gyrase inhibitors
- new mono
- bicyclic dna
- bicyclic
- Prior art date
Links
- 125000002619 bicyclic group Chemical group 0.000 title 1
- 239000002271 gyrase inhibitor Substances 0.000 title 1
- 125000002950 monocyclic group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94104995 | 1994-03-30 | ||
| EP95101595 | 1995-02-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI951514A0 FI951514A0 (fi) | 1995-03-30 |
| FI951514A true FI951514A (fi) | 1995-10-01 |
Family
ID=26135552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI951514A FI951514A (fi) | 1994-03-30 | 1995-03-30 | Uusia mono- ja bisyklisiä DNA-gyraasiinhibiittoreita |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US5589473A (fi) |
| EP (1) | EP0675122A3 (fi) |
| JP (1) | JP2695132B2 (fi) |
| KR (1) | KR950032185A (fi) |
| CN (2) | CN1114648A (fi) |
| AU (1) | AU694936B2 (fi) |
| CA (1) | CA2144499A1 (fi) |
| CZ (1) | CZ78895A3 (fi) |
| FI (1) | FI951514A (fi) |
| HU (1) | HUT72491A (fi) |
| IL (1) | IL113123A (fi) |
| NO (1) | NO304024B1 (fi) |
| NZ (1) | NZ270801A (fi) |
| RU (1) | RU95104899A (fi) |
| TW (1) | TW343965B (fi) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9601724D0 (en) * | 1996-01-29 | 1996-03-27 | Merck Sharp & Dohme | Therapeutic agents |
| US5922883A (en) * | 1996-04-03 | 1999-07-13 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| JP4851933B2 (ja) | 2003-04-11 | 2012-01-11 | ピーティーシー セラピューティクス，インコーポレーテッド | １，２，４−オキサジアゾール安息香酸化合物ならびにナンセンス抑制及び疾患の治療のためのその使用 |
| GB0325830D0 (en) * | 2003-11-05 | 2003-12-10 | Novartis Ag | Organic compounds |
| FR2866887A1 (fr) * | 2004-02-27 | 2005-09-02 | Oreal | Para-phenylenediamine secondaire n-heteroaryle, compositon tinctoriale comprenant une telle para-phenylenediamine, procede mettant en oeuvre cette composition et utilisation |
| US7329288B2 (en) | 2004-02-27 | 2008-02-12 | L'oreal S.A. | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof |
| GB0500683D0 (en) | 2005-01-13 | 2005-02-23 | Novartis Ag | Organic compounds |
| CA2594943A1 (en) * | 2005-01-19 | 2006-07-27 | Merck & Co., Inc. | Aminomethyl beta-secretase inhibitors for the treatment of alzheimer's disease |
| CN101184487B (zh) * | 2005-03-31 | 2010-11-03 | 詹森药业有限公司 | 作为抗菌剂的二环吡唑化合物 |
| CA2647903C (en) | 2006-03-30 | 2016-12-13 | Ptc Therapeutics, Inc. | Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith |
| US7829709B1 (en) * | 2007-08-10 | 2010-11-09 | Marquette University | Cysteine prodrugs to treat schizophrenia and drug addiction |
| JP5796881B2 (ja) * | 2008-02-07 | 2015-10-21 | マーケット ユニバーシティー | 統合失調症を治療するため及び薬物渇望を低減するためのシステイン及びシスチンプロドラッグ |
| WO2009137251A2 (en) * | 2008-04-16 | 2009-11-12 | Marquette University | Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings |
| WO2012021704A1 (en) | 2010-08-12 | 2012-02-16 | Enanta Pharmaceuticals, Inc. | Hepatitis c virus inhibitors |
| KR101604119B1 (ko) * | 2011-06-14 | 2016-03-16 | 주식회사 녹십자 | 신규한 c-아릴 안사 sglt2 억제제 |
| RS57816B1 (sr) | 2013-05-10 | 2018-12-31 | Karus Therapeutics Ltd | Inhibitori histon deacetilaze |
| WO2015134711A1 (en) | 2014-03-06 | 2015-09-11 | Ptc Therapeutics, Inc. | Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid |
| GB201419228D0 (en) * | 2014-10-29 | 2014-12-10 | Karus Therapeutics Ltd | Compounds |
| MX2018005361A (es) | 2015-10-30 | 2018-06-07 | Ptc Therapeutics Inc | Metodos para tratar epilepsia. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992018490A1 (en) * | 1991-04-17 | 1992-10-29 | F. Hoffmann-La Roche Ag | Novel dna gyrase inhibitors, process for their manufacture and pharmaceutical preparations containing same |
-
1995
- 1995-03-10 TW TW084102306A patent/TW343965B/zh active
- 1995-03-13 CA CA002144499A patent/CA2144499A1/en not_active Abandoned
- 1995-03-15 EP EP95103702A patent/EP0675122A3/en not_active Withdrawn
- 1995-03-20 US US08/407,730 patent/US5589473A/en not_active Expired - Fee Related
- 1995-03-24 IL IL11312395A patent/IL113123A/xx not_active IP Right Cessation
- 1995-03-24 HU HU9500860A patent/HUT72491A/hu unknown
- 1995-03-24 NZ NZ270801A patent/NZ270801A/en unknown
- 1995-03-24 AU AU15070/95A patent/AU694936B2/en not_active Ceased
- 1995-03-29 RU RU95104899/09A patent/RU95104899A/ru unknown
- 1995-03-29 CZ CZ95788A patent/CZ78895A3/cs unknown
- 1995-03-29 NO NO951210A patent/NO304024B1/no not_active IP Right Cessation
- 1995-03-29 KR KR1019950006839A patent/KR950032185A/ko not_active Application Discontinuation
- 1995-03-30 CN CN95104354A patent/CN1114648A/zh active Pending
- 1995-03-30 FI FI951514A patent/FI951514A/fi unknown
- 1995-03-30 JP JP7073217A patent/JP2695132B2/ja not_active Expired - Lifetime
- 1995-10-11 US US08/541,077 patent/US5594135A/en not_active Expired - Fee Related
- 1995-10-11 US US08/540,678 patent/US5665746A/en not_active Expired - Fee Related
-
2000
- 2000-12-01 CN CN00135099A patent/CN1308071A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US5589473A (en) | 1996-12-31 |
| RU95104899A (ru) | 1997-01-10 |
| KR950032185A (ko) | 1995-12-20 |
| AU694936B2 (en) | 1998-08-06 |
| IL113123A (en) | 1999-11-30 |
| JPH07285953A (ja) | 1995-10-31 |
| CN1114648A (zh) | 1996-01-10 |
| CZ78895A3 (en) | 1995-12-13 |
| EP0675122A2 (en) | 1995-10-04 |
| CA2144499A1 (en) | 1995-10-01 |
| US5594135A (en) | 1997-01-14 |
| EP0675122A3 (en) | 1997-11-05 |
| US5665746A (en) | 1997-09-09 |
| NZ270801A (en) | 1997-01-29 |
| HUT72491A (en) | 1996-05-28 |
| NO951210L (no) | 1995-10-02 |
| JP2695132B2 (ja) | 1997-12-24 |
| CN1308071A (zh) | 2001-08-15 |
| TW343965B (en) | 1998-11-01 |
| IL113123A0 (en) | 1995-06-29 |
| FI951514A0 (fi) | 1995-03-30 |
| HU9500860D0 (en) | 1995-05-29 |
| NO951210D0 (no) | 1995-03-29 |
| NO304024B1 (no) | 1998-10-12 |
| AU1507095A (en) | 1995-10-12 |
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