FI950229A0 - Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineina - Google Patents
Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistamiseksi ja niiden käyttö kasvaintenvastaisina aineinaInfo
- Publication number
- FI950229A0 FI950229A0 FI950229A FI950229A FI950229A0 FI 950229 A0 FI950229 A0 FI 950229A0 FI 950229 A FI950229 A FI 950229A FI 950229 A FI950229 A FI 950229A FI 950229 A0 FI950229 A0 FI 950229A0
- Authority
- FI
- Finland
- Prior art keywords
- intermediates
- processes
- preparation
- antitumor agents
- tetracyclic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929215361A GB9215361D0 (en) | 1992-07-20 | 1992-07-20 | Heterocyclic compounds |
| PCT/GB1993/001512 WO1994002483A1 (en) | 1992-07-20 | 1993-07-19 | Tetracyclic compounds process and intermediates for their preparation and their use as antitumour agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI950229A0 true FI950229A0 (fi) | 1995-01-19 |
| FI950229L FI950229L (fi) | 1995-03-10 |
| FI950229A7 FI950229A7 (fi) | 1995-03-10 |
Family
ID=10718981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI950229A FI950229A7 (fi) | 1992-07-20 | 1993-07-19 | Tetrasyklisiä yhdisteitä, menetelmä ja välituotteita niiden valmistami seksi ja niiden käyttö kasvaintenvastaisina aineina |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0651750A1 (fi) |
| JP (1) | JPH08502037A (fi) |
| KR (1) | KR950702563A (fi) |
| CN (1) | CN1088209A (fi) |
| AU (1) | AU4579593A (fi) |
| BG (1) | BG99359A (fi) |
| CA (1) | CA2140662A1 (fi) |
| CZ (1) | CZ14995A3 (fi) |
| FI (1) | FI950229A7 (fi) |
| GB (1) | GB9215361D0 (fi) |
| HR (1) | HRP931066A2 (fi) |
| HU (1) | HUT76787A (fi) |
| IL (1) | IL106385A0 (fi) |
| MX (1) | MX9304355A (fi) |
| NO (1) | NO950202D0 (fi) |
| NZ (1) | NZ254207A (fi) |
| PL (1) | PL307169A1 (fi) |
| RU (1) | RU95104939A (fi) |
| SI (1) | SI9300390A (fi) |
| SK (1) | SK7595A3 (fi) |
| WO (1) | WO1994002483A1 (fi) |
| YU (1) | YU50293A (fi) |
| ZA (1) | ZA935213B (fi) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9401921D0 (en) * | 1994-02-01 | 1994-03-30 | Wellcome Found | Heterocyclic compounds |
| GB9413758D0 (en) * | 1994-07-07 | 1994-08-24 | Wellcome Found | Heterocyclic compounds |
| GB9804343D0 (en) * | 1998-02-27 | 1998-04-22 | Univ Cardiff | Chemical compounds |
| ATE431823T1 (de) * | 2001-02-14 | 2009-06-15 | Wisconsin Alumni Res Found | Zubereitungen und verwendung eines ah-rezeptor- liganden, 2-(1'h-indol-3'-carbonyl)-thiazol-4- carbonsäure-methylester |
| US7419992B2 (en) | 2001-02-14 | 2008-09-02 | Wisconsin Alumni Research Foundation | Use of aryl hydrocarbon receptor ligand as a therapeutic intervention in angiogenesis-implicated disorders |
| GB0302094D0 (en) | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| GB0324269D0 (en) | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| US20100130579A1 (en) * | 2006-10-23 | 2010-05-27 | Georgetown University | Cancer therapy |
| BRPI0917411A2 (pt) | 2008-08-15 | 2015-12-01 | Univ Georgetown | composto de dansil-carbazol, método para tratamento de câncer em um sujeito, método para reduzir atividade de mentiltransferase de dna em uma célula, método para aumentar expressão da associação de dominio da familia 1a(rassf1a) em uma célula, métodos de identificação de célula, método de determinação se uma ou mais células de um sujeito são células cancerosas, composição farmacêutica e kit. |
| JP2012051804A (ja) * | 2008-12-26 | 2012-03-15 | Kyoto Univ | Ｅｇ５阻害剤 |
| KR20160066490A (ko) | 2014-12-02 | 2016-06-10 | 주식회사 씨앤드씨신약연구소 | 헤테로사이클 유도체 및 그의 용도 |
| US11053255B2 (en) | 2015-06-22 | 2021-07-06 | Georgetown University | Synthesis of mahanine and related compounds |
| CN109776550B (zh) * | 2019-01-17 | 2021-08-10 | 广东轻工职业技术学院 | 一种海洋真菌来源的生物碱化合物及其在制备食品防腐剂中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0300688A1 (en) * | 1987-07-21 | 1989-01-25 | FISONS plc | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them |
| GB2239013B (en) * | 1989-11-01 | 1993-06-02 | Toyama Chemical Co Ltd | Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same |
| EP0447703A1 (en) * | 1990-03-20 | 1991-09-25 | The Wellcome Foundation Limited | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine |
-
1992
- 1992-07-20 GB GB929215361A patent/GB9215361D0/en active Pending
-
1993
- 1993-07-19 KR KR1019950700226A patent/KR950702563A/ko not_active Withdrawn
- 1993-07-19 WO PCT/GB1993/001512 patent/WO1994002483A1/en not_active Application Discontinuation
- 1993-07-19 MX MX9304355A patent/MX9304355A/es not_active IP Right Cessation
- 1993-07-19 RU RU95104939/04A patent/RU95104939A/ru unknown
- 1993-07-19 NZ NZ254207A patent/NZ254207A/en unknown
- 1993-07-19 HR HR931066A patent/HRP931066A2/hr not_active Application Discontinuation
- 1993-07-19 ZA ZA935213A patent/ZA935213B/xx unknown
- 1993-07-19 CA CA002140662A patent/CA2140662A1/en not_active Abandoned
- 1993-07-19 CN CN93116598A patent/CN1088209A/zh active Pending
- 1993-07-19 EP EP93916105A patent/EP0651750A1/en not_active Withdrawn
- 1993-07-19 JP JP6504272A patent/JPH08502037A/ja active Pending
- 1993-07-19 IL IL106385A patent/IL106385A0/xx unknown
- 1993-07-19 CZ CZ95149A patent/CZ14995A3/cs unknown
- 1993-07-19 HU HU9500171A patent/HUT76787A/hu unknown
- 1993-07-19 SK SK75-95A patent/SK7595A3/sk unknown
- 1993-07-19 AU AU45795/93A patent/AU4579593A/en not_active Abandoned
- 1993-07-19 PL PL93307169A patent/PL307169A1/xx unknown
- 1993-07-19 FI FI950229A patent/FI950229A7/fi unknown
- 1993-07-19 SI SI9300390A patent/SI9300390A/sl unknown
- 1993-07-20 YU YU50293A patent/YU50293A/sh unknown
-
1995
- 1995-01-18 BG BG99359A patent/BG99359A/bg unknown
- 1995-01-19 NO NO950202A patent/NO950202D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI9300390A (en) | 1994-03-31 |
| FI950229L (fi) | 1995-03-10 |
| ZA935213B (en) | 1995-01-19 |
| PL307169A1 (en) | 1995-05-15 |
| SK7595A3 (en) | 1995-07-11 |
| MX9304355A (es) | 1994-04-29 |
| JPH08502037A (ja) | 1996-03-05 |
| WO1994002483A1 (en) | 1994-02-03 |
| GB9215361D0 (en) | 1992-09-02 |
| KR950702563A (ko) | 1995-07-29 |
| NO950202L (no) | 1995-01-19 |
| RU95104939A (ru) | 1996-10-27 |
| HU9500171D0 (en) | 1995-03-28 |
| AU4579593A (en) | 1994-02-14 |
| CN1088209A (zh) | 1994-06-22 |
| NZ254207A (en) | 1997-03-24 |
| HUT76787A (en) | 1997-11-28 |
| NO950202D0 (no) | 1995-01-19 |
| YU50293A (sh) | 1997-01-08 |
| CA2140662A1 (en) | 1994-02-03 |
| HRP931066A2 (en) | 1995-12-31 |
| BG99359A (bg) | 1995-11-30 |
| FI950229A7 (fi) | 1995-03-10 |
| CZ14995A3 (en) | 1995-10-18 |
| EP0651750A1 (en) | 1995-05-10 |
| IL106385A0 (en) | 1993-11-15 |
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