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FI945353A - Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid - Google Patents

Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid Download PDF

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Publication number
FI945353A
FI945353A FI945353A FI945353A FI945353A FI 945353 A FI945353 A FI 945353A FI 945353 A FI945353 A FI 945353A FI 945353 A FI945353 A FI 945353A FI 945353 A FI945353 A FI 945353A
Authority
FI
Finland
Prior art keywords
methoxyl
alpha
methyl
preparation
enzymatic process
Prior art date
Application number
FI945353A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI945353A0 (en
Inventor
Hardy W Chan
Richard Freedman
Felix H Salazar
Steven R Beck
Robert O Cain
Christopher R Roberts
Roger C Synder
Patricia Phelps
Donald L Heefner
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of FI945353A0 publication Critical patent/FI945353A0/en
Publication of FI945353A publication Critical patent/FI945353A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02BINTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00Other engines
    • F02B75/02Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI945353A 1992-05-15 1994-11-14 Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid FI945353A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88365892A 1992-05-15 1992-05-15
PCT/US1993/004392 WO1993023547A1 (en) 1992-05-15 1993-05-14 ENZYMATIC PROCESS FOR PRODUCTION OF S-6-METHOXY-α-METHYL-2-NAPHTHALENEACETIC ACID

Publications (2)

Publication Number Publication Date
FI945353A0 FI945353A0 (en) 1994-11-14
FI945353A true FI945353A (en) 1994-11-14

Family

ID=25383055

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945353A FI945353A (en) 1992-05-15 1994-11-14 Enzymatic process for the preparation of (S) -6-methoxyl-alpha-methyl-2-naphthaleneacetic acid

Country Status (5)

Country Link
EP (1) EP0644940A1 (en)
FI (1) FI945353A (en)
MX (1) MX9302853A (en)
NO (1) NO944336D0 (en)
WO (1) WO1993023547A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912164A (en) * 1993-03-03 1999-06-15 Laboratorios Menarini S.A. Stereoselective hydrolysis of chiral carboxylic acid esters using esterase from ophiostoma or ceratocystis
GB9304351D0 (en) * 1993-03-03 1993-04-21 Chiros Ltd Arylalkanoic acid resolution and microorganisms for use therein
WO2011041231A1 (en) * 2009-09-30 2011-04-07 Codexis, Inc. Variant lovd polypeptides and their uses
CN103937845B (en) * 2014-04-24 2016-06-22 哈尔滨商业大学 S-(+) preparation method of-naproxen acylglycerol ester prodrugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81049A0 (en) * 1985-12-20 1987-03-31 Wisconsin Alumni Res Found Preparation of(s)-alpha-methylarylacetic acids
US5229280A (en) * 1988-02-25 1993-07-20 Istituto Guido Donegani S.P.A. Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
FI95931C (en) * 1988-09-02 1996-04-10 Tanabe Seiyaku Co Process for the preparation of the lower alkyl ester of (2R, 3S) -3- (4-methoxyphenyl) glycidic acid

Also Published As

Publication number Publication date
WO1993023547A1 (en) 1993-11-25
NO944336L (en) 1994-11-14
MX9302853A (en) 1993-11-01
NO944336D0 (en) 1994-11-14
FI945353A0 (en) 1994-11-14
EP0644940A1 (en) 1995-03-29

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Legal Events

Date Code Title Description
FD Application lapsed