FI944656L - Uudet kardioprotektiivset aineet - Google Patents

Uudet kardioprotektiivset aineet Download PDF

Info

Publication number: FI944656L
Authority: FI; Finland
Prior art keywords: cardioprotective agents; new; new cardioprotective; agents; cardioprotective
Prior art date: 1992-04-06

Application number

FI944656A

Other languages

English (en)

Swedish (sv)

Other versions

FI944656A0 (fi

FI112658B (fi

Inventor

J Martin Grisar

Margaret A Petty

Frank Bolkenius

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-06

Filing date

1994-10-05

Publication date

1994-10-05

1994-10-05 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1994-10-05 Publication of FI944656A0 publication Critical patent/FI944656A0/fi

1994-10-05 Publication of FI944656L publication Critical patent/FI944656L/fi

2003-12-31 Application granted granted Critical

2003-12-31 Publication of FI112658B publication Critical patent/FI112658B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Polyesters Or Polycarbonates (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Paints Or Removers (AREA)
Investigating Or Analysing Biological Materials (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

FI944656A 1992-04-06 1994-10-05 Menetelmä uusien kardioprotektiivisten hydroksibentsopyraani-2-karboksyylihappojohdannaisten ja niiden laktonien valmistamiseksi FI112658B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP92400957		1992-04-06
EP92400957		1992-04-06
US9302102		1993-03-08
PCT/US1993/002102 WO1993020058A1 (en)	1992-04-06	1993-03-08	Novel cardioprotective agents

Publications (3)

Publication Number	Publication Date
FI944656A0 FI944656A0 (fi)	1994-10-05
FI944656L true FI944656L (fi)	1994-10-05
FI112658B FI112658B (fi)	2003-12-31

Family

ID=8211647

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI944656A FI112658B (fi)	1992-04-06	1994-10-05	Menetelmä uusien kardioprotektiivisten hydroksibentsopyraani-2-karboksyylihappojohdannaisten ja niiden laktonien valmistamiseksi

Country Status (18)

Country	Link
EP (1)	EP0635010B1 (fi)
JP (1)	JP3248183B2 (fi)
KR (1)	KR100243820B1 (fi)
AT (1)	ATE146175T1 (fi)
AU (1)	AU667889B2 (fi)
CA (1)	CA2132745C (fi)
DE (1)	DE69306559T2 (fi)
DK (1)	DK0635010T3 (fi)
ES (1)	ES2098030T3 (fi)
FI (1)	FI112658B (fi)
GR (1)	GR3022471T3 (fi)
HU (1)	HU217426B (fi)
IL (1)	IL105320A (fi)
NO (1)	NO307088B1 (fi)
NZ (1)	NZ251131A (fi)
TW (1)	TW232014B (fi)
WO (1)	WO1993020058A1 (fi)
ZA (1)	ZA932326B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5721233A (en) *	1992-04-06	1998-02-24	Merrell Pharmaceuticals Inc.	Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) *	1992-04-07	1996-08-13	Merrell Pharmaceuticals Inc.	Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
US5451603A (en) *	1993-03-11	1995-09-19	Zymogenetics, Inc.	3,4-diarylchromans for treatment of dermatitis
US5416098A (en) *	1993-12-30	1995-05-16	Zymogenetics, Inc.	Method for treating dermatitis and related conditions
CN115073413B (zh) *	2022-05-17	2023-06-02	中山大学	一种苯并环醚类倍半萜类化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3947473A (en) *	1972-12-22	1976-03-30	Hoffman-La Roche Inc.	Antioxidant chroman compounds
CA2002649C (en) *	1988-11-14	2000-06-06	Margaret Petty	Cardioprotective tocopherol analogs

1993
- 1993-03-08 AT AT93907332T patent/ATE146175T1/de not_active IP Right Cessation
- 1993-03-08 WO PCT/US1993/002102 patent/WO1993020058A1/en active IP Right Grant
- 1993-03-08 JP JP51745193A patent/JP3248183B2/ja not_active Expired - Fee Related
- 1993-03-08 AU AU37972/93A patent/AU667889B2/en not_active Ceased
- 1993-03-08 HU HU9402863A patent/HU217426B/hu not_active IP Right Cessation
- 1993-03-08 ES ES93907332T patent/ES2098030T3/es not_active Expired - Lifetime
- 1993-03-08 KR KR1019940703514A patent/KR100243820B1/ko not_active Expired - Fee Related
- 1993-03-08 DK DK93907332.6T patent/DK0635010T3/da active
- 1993-03-08 DE DE69306559T patent/DE69306559T2/de not_active Expired - Lifetime
- 1993-03-08 EP EP93907332A patent/EP0635010B1/en not_active Expired - Lifetime
- 1993-03-08 NZ NZ251131A patent/NZ251131A/en unknown
- 1993-03-08 CA CA002132745A patent/CA2132745C/en not_active Expired - Lifetime
- 1993-03-31 ZA ZA932326A patent/ZA932326B/xx unknown
- 1993-04-01 TW TW082102447A patent/TW232014B/zh active
- 1993-04-05 IL IL105320A patent/IL105320A/en not_active IP Right Cessation
1994
- 1994-10-05 NO NO943727A patent/NO307088B1/no unknown
- 1994-10-05 FI FI944656A patent/FI112658B/fi not_active IP Right Cessation
1997
- 1997-02-05 GR GR960403605T patent/GR3022471T3/el unknown

Also Published As

Publication number	Publication date
ES2098030T3 (es)	1997-04-16
ATE146175T1 (de)	1996-12-15
WO1993020058A1 (en)	1993-10-14
ZA932326B (en)	1993-10-18
NO943727D0 (no)	1994-10-05
FI944656A0 (fi)	1994-10-05
IL105320A0 (en)	1993-08-18
EP0635010B1 (en)	1996-12-11
DE69306559T2 (de)	1997-04-10
NO943727L (no)	1994-12-05
KR100243820B1 (ko)	2000-03-02
IL105320A (en)	1998-02-08
CA2132745C (en)	2000-03-21
TW232014B (fi)	1994-10-11
JPH07505392A (ja)	1995-06-15
JP3248183B2 (ja)	2002-01-21
NO307088B1 (no)	2000-02-07
CA2132745A1 (en)	1993-10-14
KR950700896A (ko)	1995-02-20
FI112658B (fi)	2003-12-31
DK0635010T3 (da)	1996-12-30
AU667889B2 (en)	1996-04-18
DE69306559D1 (de)	1997-01-23
GR3022471T3 (en)	1997-05-31
EP0635010A1 (en)	1995-01-25
HU9402863D0 (en)	1995-01-30
HU217426B (hu)	2000-01-28
AU3797293A (en)	1993-11-08
HUT68982A (en)	1995-08-28
NZ251131A (en)	1996-01-26

Publication	Publication Date	Title
FI935768L (fi)	1993-12-21	I fysiologisk omgivning upploesande mineralfibrer
FI931968L (fi)	1993-11-03	Foerbaettringar i radiostaempling
DK0558811T3 (da)	1995-09-11	Etskærsrival
FI931711A0 (fi)	1993-04-15	Stoedfot foer kran i kompositmaterial
FI933038A0 (fi)	1993-07-01	Matningssystem foer presspartiet i en pappermaskin
FI923978L (fi)	1994-03-05	Effektekonomi i mobilteleapparat
FI923709L (fi)	1994-02-20	I en saekerhetsskena laosbar vagn
FI933709L (fi)	1994-02-25	Haollare foer vaevbladet i en soemvaevmaskin
FI931058A0 (fi)	1993-03-10	Rakelbalk foer faergningsanordningen i en tryckmaskin
FI944656L (fi)	1994-10-05	Uudet kardioprotektiivset aineet
FI935002A7 (fi)	1994-05-13	Justerbar solvstyranordning foer jacquardmaskinen i en soemvaevstol
FI933485A0 (fi)	1993-08-06	Avrinningsinsats foer montering i existerande avrinningsbassaeng
DE59304139D1 (de)	1996-11-14	Polyanile
DE69307670D1 (de)	1997-03-06	Ölbehälter
FI925685A0 (fi)	1992-12-15	Foerfarande i foerbraenningsmotorprocess
KR930018348U (ko)	1993-08-21	와 셔
KR940015972U (ko)	1994-07-22	세탁기
FI922527L (fi)	1993-12-02	Vaeggkonstruktion foer anordning i byggnader
DK124992D0 (da)	1992-10-12	Anhugningshsoved
ITTO920703A1 (it)	1994-02-19	Toponomastica internazionale
FI377U1 (fi)	1992-11-20	Bakgrundselement foer vaermebatterier i byggnader
FI802U1 (fi)	1993-07-12	Appliceringsbalk i en limpress
FI717U1 (fi)	1993-05-12	Lucka foer montering i takplaot
FI291U1 (fi)	1992-10-06	Utloppsfoerbindning i en substitutionsluftinslaeppningsventil
FI31U1 (fi)	1992-02-20	Anordning i framlastare

Legal Events

Date	Code	Title	Description
2004-09-30	MA	Patent expired