FI943645L - Novel baccatin-III and 10-deacetylbaccatin-III derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
Novel baccatin-III and 10-deacetylbaccatin-III derivatives, their preparation and pharmaceutical compositions containing them Download PDFInfo
- Publication number
- FI943645L FI943645L FI943645A FI943645A FI943645L FI 943645 L FI943645 L FI 943645L FI 943645 A FI943645 A FI 943645A FI 943645 A FI943645 A FI 943645A FI 943645 L FI943645 L FI 943645L
- Authority
- FI
- Finland
- Prior art keywords
- iii
- deacetylbaccatin
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- OVMSOCFBDVBLFW-VHLOTGQHSA-N 5beta,20-epoxy-1,7beta,13alpha-trihydroxy-9-oxotax-11-ene-2alpha,4alpha,10beta-triyl 4,10-diacetate 2-benzoate Chemical compound O([C@@H]1[C@@]2(C[C@H](O)C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)O)C(=O)C1=CC=CC=C1 OVMSOCFBDVBLFW-VHLOTGQHSA-N 0.000 title 2
- YWLXLRUDGLRYDR-ZHPRIASZSA-N 5beta,20-epoxy-1,7beta,10beta,13alpha-tetrahydroxy-9-oxotax-11-ene-2alpha,4alpha-diyl 4-acetate 2-benzoate Chemical class O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](O)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 YWLXLRUDGLRYDR-ZHPRIASZSA-N 0.000 title 1
- 229930014667 baccatin III Natural products 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9201381A FR2687151B1 (en) | 1992-02-07 | 1992-02-07 | NOVEL DERIVATIVES OF BACCATIN III AND DESACETYL-10 BACCATIN III, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| PCT/FR1993/000112 WO1993016060A1 (en) | 1992-02-07 | 1993-02-04 | Novel baccatine iii and 10-deacetyl baccatine iii derivatives, their preparation, and pharmaceutical compositions containing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI943645A0 FI943645A0 (en) | 1994-08-05 |
| FI943645L true FI943645L (en) | 1994-08-05 |
Family
ID=9426426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI943645A FI943645L (en) | 1992-02-07 | 1994-08-05 | Novel baccatin-III and 10-deacetylbaccatin-III derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0625148A1 (en) |
| JP (1) | JPH07503477A (en) |
| AU (1) | AU3505093A (en) |
| CA (1) | CA2127372A1 (en) |
| CZ (1) | CZ187294A3 (en) |
| FI (1) | FI943645L (en) |
| FR (1) | FR2687151B1 (en) |
| HU (1) | HU9402292D0 (en) |
| MX (1) | MX9300628A (en) |
| NO (1) | NO942910L (en) |
| SK (1) | SK92794A3 (en) |
| TW (1) | TW242139B (en) |
| WO (1) | WO1993016060A1 (en) |
| ZA (1) | ZA93821B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698582A (en) * | 1991-07-08 | 1997-12-16 | Rhone-Poulenc Rorer S.A. | Compositions containing taxane derivatives |
| US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
| FR2696459B1 (en) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Process for the preparation of taxane derivatives. |
| IL107950A (en) | 1992-12-15 | 2001-04-30 | Upjohn Co | 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US5684175A (en) * | 1993-02-05 | 1997-11-04 | Napro Biotherapeutics, Inc. | C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor |
| DE69433297T2 (en) | 1993-02-05 | 2004-10-21 | Bryn Mawr College Bryn Mawr | SYNTHESIS OF TAXOL, ITS ANALOGS AND INTERMEDIATES WITH VARIABLE A-RING SIDE CHAINS |
| ES2145829T3 (en) * | 1993-06-11 | 2000-07-16 | Upjohn Co | ANTINEOPLASIC USE OF DELTA 6,7-TAXOLS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. |
| IL112412A (en) * | 1994-01-28 | 2000-02-29 | Upjohn Co | Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them |
| GB9512471D0 (en) * | 1995-06-20 | 1995-08-23 | Pharmacia Spa | Method for the preparation of taxol and its derivatives |
| US6107497A (en) * | 1996-02-29 | 2000-08-22 | Napro Biotherapeutics, Inc. | Intermediate for use in docetaxel synthesis and production method therefor |
| US6025385A (en) * | 1996-07-15 | 2000-02-15 | Kabushiki Kaisha Yakult Honsha | Taxane derivatives and drugs containing the same |
| US5750737A (en) * | 1996-09-25 | 1998-05-12 | Sisti; Nicholas J. | Method for paclitaxel synthesis |
| JPH1192468A (en) * | 1997-09-17 | 1999-04-06 | Yakult Honsha Co Ltd | New taxane derivatives |
| WO2002066448A1 (en) * | 2001-02-20 | 2002-08-29 | Dabur India Limited | Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid |
| CN101835769A (en) * | 2007-08-22 | 2010-09-15 | 6570763加拿大有限公司 | Method for converting 9-dihydro-13-acetylbaccatin III into docetaxel or paclitaxel |
| EP2276755A4 (en) * | 2008-03-31 | 2011-05-04 | Univ Florida State Res Found | TAXANES SUBSTITUTED WITH C (10) ETHYL ESTER AND C (10) CYCLOPROPYL ESTER |
-
1992
- 1992-02-07 FR FR9201381A patent/FR2687151B1/en not_active Expired - Fee Related
-
1993
- 1993-02-04 AU AU35050/93A patent/AU3505093A/en not_active Abandoned
- 1993-02-04 TW TW082100756A patent/TW242139B/zh active
- 1993-02-04 EP EP93904152A patent/EP0625148A1/en not_active Withdrawn
- 1993-02-04 WO PCT/FR1993/000112 patent/WO1993016060A1/en not_active Application Discontinuation
- 1993-02-04 MX MX9300628A patent/MX9300628A/en unknown
- 1993-02-04 JP JP5513823A patent/JPH07503477A/en active Pending
- 1993-02-04 CZ CZ941872A patent/CZ187294A3/en unknown
- 1993-02-04 SK SK927-94A patent/SK92794A3/en unknown
- 1993-02-04 HU HU9402292A patent/HU9402292D0/en unknown
- 1993-02-04 CA CA002127372A patent/CA2127372A1/en not_active Abandoned
- 1993-02-05 ZA ZA93821A patent/ZA93821B/en unknown
-
1994
- 1994-08-05 NO NO942910A patent/NO942910L/en unknown
- 1994-08-05 FI FI943645A patent/FI943645L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1993016060A1 (en) | 1993-08-19 |
| HU9402292D0 (en) | 1994-11-28 |
| FI943645A0 (en) | 1994-08-05 |
| AU3505093A (en) | 1993-09-03 |
| CA2127372A1 (en) | 1993-08-19 |
| FR2687151A1 (en) | 1993-08-13 |
| NO942910D0 (en) | 1994-08-05 |
| ZA93821B (en) | 1993-09-09 |
| CZ187294A3 (en) | 1995-01-18 |
| SK92794A3 (en) | 1995-04-12 |
| JPH07503477A (en) | 1995-04-13 |
| EP0625148A1 (en) | 1994-11-23 |
| MX9300628A (en) | 1993-08-01 |
| FR2687151B1 (en) | 1994-03-25 |
| TW242139B (en) | 1995-03-01 |
| NO942910L (en) | 1994-08-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI942913A0 (en) | Isatin derivatives, methods for their preparation and pharmaceutical compositions containing them | |
| FI943571A0 (en) | 1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivatives, their preparation and pharmaceutical compositions containing them | |
| IL99225A0 (en) | 3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them | |
| ZA923513B (en) | New thiopyranopyrrole derivatives,their preparation and pharmaceutical compositions containing them | |
| EE03177B1 (en) | Heterobicyclic compounds, methods for their preparation and pharmaceutical compositions containing said compounds | |
| FI952920L (en) | 7-Halo- and 7beta,8beta-methano-taxols, their antineoplastic use and pharmaceutical compositions containing them | |
| IL106141A0 (en) | Thiazolylvinylphenyl derivatives,their manufacture and pharmaceutical compositions containing them | |
| IL100262A0 (en) | Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them | |
| IL97050A0 (en) | 4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation | |
| IL98542A0 (en) | Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them | |
| FI951789A0 (en) | Novel taxane derivatives, their preparation and pharmaceutical compositions containing them | |
| FI943688L (en) | New 11-benzaldoxime-17beta-methoxy-27alpha-methoxy-methyl-estradiene derivatives, processes for their preparation and pharmaceutical compositions containing them | |
| IL98756A0 (en) | Pharmaceutical compositions containing benzeneacetamid derivatives,certain such novel compounds and their preparation | |
| IL108703A0 (en) | Substituted azolone derivatives, their preparation and pharmaceutical compositions containing them | |
| FI943645L (en) | Novel baccatin-III and 10-deacetylbaccatin-III derivatives, their preparation and pharmaceutical compositions containing them | |
| IL104356A0 (en) | Benzofuranyl-and thiophenylmethylthio-alkanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL102500A0 (en) | 3-deoxy-mannosamine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL104406A0 (en) | Substituted 1-isoquinolone derivatives,their preparation and pharmaceutical compositions containing them | |
| FI960316A0 (en) | Oxathiolanes, process for their preparation and pharmaceutical compositions containing them | |
| FI945439L (en) | New taxane derivatives, their preparation and compositions containing them | |
| IL105774A0 (en) | Thienothiazine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL106549A0 (en) | Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them | |
| FI951561A0 (en) | Novel 17-substituted 4-androstane derivatives, pharmaceutical compositions containing them and process for their preparation | |
| IL105370A0 (en) | Propenoyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL104347A0 (en) | Substituted benzimidazole derivatives,their preparation and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |