FI940075A - Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi - Google Patents

Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi Download PDF

Info

Publication number: FI940075A
Authority: FI; Finland
Prior art keywords: iii; preparation; desacetylbaccatin; baccatin; general formula
Prior art date: 1991-07-10

Application number

FI940075A

Other languages

English (en)

Swedish (sv)

Other versions

FI109792B (fi

FI940075A0 (fi

Inventor

Augustin Hittinger

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-10

Filing date

1994-01-07

Publication date

1994-01-07

1994-01-07 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1994-01-07 Publication of FI940075A publication Critical patent/FI940075A/fi

1994-01-07 Publication of FI940075A0 publication Critical patent/FI940075A0/fi

2002-10-15 Application granted granted Critical

2002-10-15 Publication of FI109792B publication Critical patent/FI109792B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epoxy Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Cephalosporin Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Saccharide Compounds (AREA)

FI940075A 1991-07-10 1994-01-07 Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi FI109792B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR9108673		1991-07-10
FR9108673A FR2678930B1 (fr)	1991-07-10	1991-07-10	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
FR9200649		1992-07-08
PCT/FR1992/000649 WO1993001179A1 (fr)	1991-07-10	1992-07-08	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii

Publications (3)

Publication Number	Publication Date
FI940075A true FI940075A (fi)	1994-01-07
FI940075A0 FI940075A0 (fi)	1994-01-07
FI109792B FI109792B (fi)	2002-10-15

Family

ID=9414931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI940075A FI109792B (fi)	1991-07-10	1994-01-07	Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi

Country Status (25)

Country	Link
US (1)	US5578739A (fi)
EP (2)	EP0593641B1 (fi)
JP (1)	JP3085710B2 (fi)
KR (1)	KR100206458B1 (fi)
AT (1)	ATE132145T1 (fi)
AU (1)	AU662346B2 (fi)
CA (1)	CA2111319C (fi)
CZ (1)	CZ281288B6 (fi)
DE (1)	DE69207194T2 (fi)
DK (1)	DK0593641T3 (fi)
ES (1)	ES2081120T3 (fi)
FI (1)	FI109792B (fi)
FR (1)	FR2678930B1 (fi)
GR (1)	GR3018543T3 (fi)
HU (1)	HU217115B (fi)
IE (1)	IE73637B1 (fi)
MX (1)	MX9204029A (fi)
NO (2)	NO934485D0 (fi)
NZ (1)	NZ243491A (fi)
PL (1)	PL169780B1 (fi)
RU (1)	RU2088578C1 (fi)
SK (1)	SK281560B6 (fi)
WO (1)	WO1993001179A1 (fi)
YU (1)	YU49175B (fi)
ZA (1)	ZA925098B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6794523B2 (en)	1991-09-23	2004-09-21	Florida State University	Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5272171A (en) *	1992-02-13	1993-12-21	Bristol-Myers Squibb Company	Phosphonooxy and carbonate derivatives of taxol
US5294637A (en) *	1992-07-01	1994-03-15	Bristol-Myers Squibb Company	Fluoro taxols
US5380751A (en) *	1992-12-04	1995-01-10	Bristol-Myers Squibb Company	6,7-modified paclitaxels
US5646176A (en)	1992-12-24	1997-07-08	Bristol-Myers Squibb Company	Phosphonooxymethyl ethers of taxane derivatives
CA2111527C (en) *	1992-12-24	2000-07-18	Jerzy Golik	Phosphonooxymethyl ethers of taxane derivatives
FR2703049B1 (fr) *	1993-03-22	1995-04-21	Rhone Poulenc Rorer Sa	Procédé de purification des taxoïdes.
CA2129288C (en) *	1993-08-17	2000-05-16	Jerzy Golik	Phosphonooxymethyl esters of taxane derivatives
FR2718135B1 (fr) *	1994-04-05	1996-04-26	Rhone Poulenc Rorer Sa	Procédé de préparation d'hydroxy-7 taxanes.
US5580899A (en) *	1995-01-09	1996-12-03	The Liposome Company, Inc.	Hydrophobic taxane derivatives
US6107332A (en)	1995-09-12	2000-08-22	The Liposome Company, Inc.	Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) *	1995-09-12	2000-04-18	Mayhew; Eric	Liposomal hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (fr) *	1995-10-27	1998-01-16	Seripharm	Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
FR2742751B1 (fr) *	1995-12-22	1998-01-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US7288665B1 (en) *	1997-08-18	2007-10-30	Florida State University	Process for selective derivatization of taxanes
US6111144A (en)	1997-08-21	2000-08-29	Florida State University	Method for the synthesis of a taxane intermediate
US5917062A (en) *	1997-11-21	1999-06-29	Indena S.P.A	Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
AU741143B2 (en) *	1998-01-14	2001-11-22	Bristol-Myers Squibb Company	Novel crystalline complexes of baccatin III with imidazole, 2-methylimidazole or isopropanol
ATE269854T1 (de) *	1998-05-01	2004-07-15	Napro Biotherapeutics Inc	Verfahren und verwendbare zwischenprodukte für paclitaxel synthese von c-7,c-10 di-cbz baccatin iii
EP1229934B1 (en)	1999-10-01	2014-03-05	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
IT1319168B1 (it) *	2000-03-17	2003-09-26	Indena Spa	Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
RU2008141912A (ru)	2006-03-23	2010-04-27	Новартис АГ (CH)	Противоопухолевые лекарства на основе антител к клеточным антигенам
DE102008013929B3 (de) *	2008-03-12	2009-04-09	Wieland-Werke Ag	Verdampferrohr mit optimierten Hinterschneidungen am Nutengrund
CN101531645B (zh) *	2009-04-29	2012-08-22	深圳万乐药业有限公司	一种多西他赛的合成方法
JP6427097B2 (ja)	2012-06-15	2018-11-21	ザブリガムアンドウィメンズホスピタルインコーポレイテッドＴｈｅＢｒｉｇｈａｍａｎｄＷｏｍｅｎ’ｓＨｏｓｐｉｔａｌ，Ｉｎｃ．	癌を処置するための組成物および該組成物を製造するための方法
JP2017513931A (ja)	2014-04-03	2017-06-01	インビクタスオンコロジーピーヴィティー．リミテッド	超分子コンビナトリアル治療薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) *	1988-04-06	1990-11-16	Centre Nat Rech Scient	Procede de preparation du taxol

1991
- 1991-07-10 FR FR9108673A patent/FR2678930B1/fr not_active Expired - Fee Related
1992
- 1992-07-08 DE DE69207194T patent/DE69207194T2/de not_active Expired - Lifetime
- 1992-07-08 ZA ZA925098A patent/ZA925098B/xx unknown
- 1992-07-08 EP EP92915477A patent/EP0593641B1/fr not_active Expired - Lifetime
- 1992-07-08 ES ES92915477T patent/ES2081120T3/es not_active Expired - Lifetime
- 1992-07-08 JP JP05502037A patent/JP3085710B2/ja not_active Expired - Lifetime
- 1992-07-08 KR KR1019940700046A patent/KR100206458B1/ko not_active IP Right Cessation
- 1992-07-08 EP EP92401958A patent/EP0522958A1/fr active Pending
- 1992-07-08 SK SK17-94A patent/SK281560B6/sk not_active IP Right Cessation
- 1992-07-08 CZ CZ9431A patent/CZ281288B6/cs not_active IP Right Cessation
- 1992-07-08 PL PL92302030A patent/PL169780B1/pl unknown
- 1992-07-08 AU AU23280/92A patent/AU662346B2/en not_active Expired
- 1992-07-08 AT AT92915477T patent/ATE132145T1/de active
- 1992-07-08 DK DK92915477.1T patent/DK0593641T3/da active
- 1992-07-08 CA CA002111319A patent/CA2111319C/fr not_active Expired - Lifetime
- 1992-07-08 WO PCT/FR1992/000649 patent/WO1993001179A1/fr active IP Right Grant
- 1992-07-08 HU HU9400062A patent/HU217115B/hu unknown
- 1992-07-08 RU RU9294016161A patent/RU2088578C1/ru active
- 1992-07-09 IE IE922234A patent/IE73637B1/en not_active IP Right Cessation
- 1992-07-09 NZ NZ243491A patent/NZ243491A/en not_active IP Right Cessation
- 1992-07-09 MX MX9204029A patent/MX9204029A/es unknown
- 1992-07-10 YU YU68792A patent/YU49175B/sh unknown
1993
- 1993-12-08 NO NO934485D patent/NO934485D0/no unknown
- 1993-12-08 NO NO934485A patent/NO302521B1/no not_active IP Right Cessation
1994
- 1994-01-07 FI FI940075A patent/FI109792B/fi not_active IP Right Cessation
1995
- 1995-07-06 US US08/498,613 patent/US5578739A/en not_active Expired - Lifetime
- 1995-12-28 GR GR950402328T patent/GR3018543T3/el unknown

Also Published As

Publication number	Publication date
HU217115B (hu)	1999-11-29
ZA925098B (en)	1993-04-28
EP0593641B1 (fr)	1995-12-27
FI109792B (fi)	2002-10-15
WO1993001179A1 (fr)	1993-01-21
CA2111319C (fr)	2003-04-08
YU49175B (sh)	2004-07-15
CA2111319A1 (fr)	1993-01-21
NO934485L (no)	1993-12-08
SK281560B6 (sk)	2001-05-10
AU2328092A (en)	1993-02-11
DE69207194D1 (de)	1996-02-08
ES2081120T3 (es)	1996-02-16
HU9400062D0 (en)	1994-05-30
NO302521B1 (no)	1998-03-16
NO934485D0 (no)	1993-12-08
HUT66018A (en)	1994-08-29
FR2678930A1 (fr)	1993-01-15
JP3085710B2 (ja)	2000-09-11
AU662346B2 (en)	1995-08-31
CZ281288B6 (cs)	1996-08-14
FR2678930B1 (fr)	1995-01-13
FI940075A0 (fi)	1994-01-07
DE69207194T2 (de)	1996-09-05
US5578739A (en)	1996-11-26
JPH06509082A (ja)	1994-10-13
DK0593641T3 (da)	1996-01-29
IE73637B1 (en)	1997-06-18
EP0522958A1 (fr)	1993-01-13
NZ243491A (en)	1995-05-26
RU2088578C1 (ru)	1997-08-27
CZ3194A3 (en)	1994-04-13
SK1794A3 (en)	1994-11-09
EP0593641A1 (fr)	1994-04-27
GR3018543T3 (en)	1996-03-31
IE922234A1 (en)	1993-01-13
ATE132145T1 (de)	1996-01-15
PL169780B1 (pl)	1996-08-30
MX9204029A (es)	1993-01-01
KR100206458B1 (ko)	1999-07-01
YU68792A (sh)	1995-10-03

Publication	Publication Date	Title
FI940075A (fi)	1994-01-07	Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi
FI924228A0 (fi)	1992-09-21	Nya substituerade taxaner och farmaceutiska kompositioner innehaollande dessa.
RU94016161A (ru)	1995-09-10	Способ получения производных iii или 10-дезацетилбаккатина iii и их применение
DK0625147T3 (da)	1996-11-11	Fremgangsmåde til fremstilling af taxanderivater
FI933903A0 (fi)	1993-09-07	Substituerade cyklohexanderivat, foerfarande foer framstaellning daerav och anvaendning av foereningar foer behandling av sjukdomar
ATE165352T1 (de)	1998-05-15	Acetylenderivate und diese enthaltende pflanzenschutzmittel
FI932992A0 (fi)	1993-06-29	Fungisida fenylbenzamider och foerfaranden foer framstaellning daerav
FR2677023B1 (fr)	1994-02-25	Derives de coumarine hydrosolubles, leur preparation et leur utilisation comme substrat d'enzyme.
NO943371D0 (no)	1994-09-12	Fremgangsmåte for fremstilling av taxanderivater
ATE170520T1 (de)	1998-09-15	Eburnan-derivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
DK0623620T3 (da)	1999-06-07	5-HT3-pyrrolopyrazinderivater
ES2098517T3 (es)	1997-05-01	Derivados de 1,2,4-tiadiazino(3,4-b)benzotiazol, su preparacion y los medicamentos que los contienen.
SE9203824L (sv)	1993-06-28	Bensofuranylimidazol-derivat, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma
FI933468A (fi)	1994-02-06	Tetrahydronaftalenderivat, framstaellning av dessa och terapeutisk anvaendning av dessa
ZA924888B (en)	1993-04-28	Process for the synthesis of enantiomers of 3-aminochroman compounds
ATE125790T1 (de)	1995-08-15	N-fumaramidsäurederivate und diese enthaltende fungizide.
BG50991A1 (en)	1993-01-15	N, n- bisubstituted derivatives of 5, 8- dimethoxy- 2- ureido- 3- hydroxy- 1, 2, 3, 4- tetrahydronaphthaline and the process for its preparation

Legal Events

Date	Code	Title	Description
2012-08-10	MA	Patent expired