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FI934298A0 - Kristallin tiagabine-hydrokloridmonohydrat, dess framstaellning och dess anvaendning - Google Patents

Kristallin tiagabine-hydrokloridmonohydrat, dess framstaellning och dess anvaendning

Info

Publication number
FI934298A0
FI934298A0 FI934298A FI934298A FI934298A0 FI 934298 A0 FI934298 A0 FI 934298A0 FI 934298 A FI934298 A FI 934298A FI 934298 A FI934298 A FI 934298A FI 934298 A0 FI934298 A0 FI 934298A0
Authority
FI
Finland
Prior art keywords
dess
crystal
hydrochloride monohydrate
anvaendning
tiagabine hydrochloride
Prior art date
Application number
FI934298A
Other languages
English (en)
Other versions
FI110096B (fi
FI934298L (fi
Inventor
Henning Petersen
Peter Nielsen
Michael Cain
R Subhash Patel
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI934298A0 publication Critical patent/FI934298A0/fi
Publication of FI934298L publication Critical patent/FI934298L/fi
Application granted granted Critical
Publication of FI110096B publication Critical patent/FI110096B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transceivers (AREA)
  • Mobile Radio Communication Systems (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
FI934298A 1991-04-02 1993-09-30 Menetelmä terapeuttisesti käyttökelpoisen kiteisen Tiagabine-hydrokloridimonohydraatin valmistamiseksi FI110096B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK58291 1991-04-02
DK91582A DK58291D0 (da) 1991-04-02 1991-04-02 Krystalinsk stof og dets fremstilling
PCT/DK1992/000093 WO1992017473A1 (en) 1991-04-02 1992-03-23 Crystalline tiagabine hydrochloride monohydrate, its preparation and use
DK9200093 1992-03-23

Publications (3)

Publication Number Publication Date
FI934298A0 true FI934298A0 (fi) 1993-09-30
FI934298L FI934298L (fi) 1993-09-30
FI110096B FI110096B (fi) 2002-11-29

Family

ID=8095193

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934298A FI110096B (fi) 1991-04-02 1993-09-30 Menetelmä terapeuttisesti käyttökelpoisen kiteisen Tiagabine-hydrokloridimonohydraatin valmistamiseksi

Country Status (15)

Country Link
US (1) US5354760A (fi)
EP (1) EP0579681B1 (fi)
AT (1) ATE180781T1 (fi)
AU (1) AU661483B2 (fi)
CA (1) CA2107223C (fi)
DE (1) DE69229339T2 (fi)
DK (2) DK58291D0 (fi)
ES (1) ES2134801T3 (fi)
FI (1) FI110096B (fi)
GR (1) GR3030919T3 (fi)
IL (1) IL101358A (fi)
NO (1) NO304113B1 (fi)
NZ (1) NZ242191A (fi)
WO (1) WO1992017473A1 (fi)
ZA (1) ZA922297B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750140A (en) * 1994-05-20 1998-05-12 Novo Nordisk A/S Transdermal delivery of tiagabine
CZ292256B6 (cs) * 1995-05-05 2003-08-13 Novo Nordisk A/S Farmaceutická směs a způsob její přípravy
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
AU736514B2 (en) * 1995-07-13 2001-07-26 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Non-allosteric gabaa agonists for treating sleep disorders
UA52661C2 (uk) * 1996-06-14 2003-01-15 Ново Нордіск А/С Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
PE20011061A1 (es) 2000-02-01 2001-11-20 Procter & Gamble Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
CN1314684C (zh) * 2003-12-24 2007-05-09 中国科学院上海有机化学研究所 噻加宾及其消旋体和s－构型的合成方法及其无定形粉末的制法
WO2005122698A2 (en) * 2003-12-24 2005-12-29 Sun Pharmaceutical Industries Limited Novel stable polymorphic forms of tiagabine hydrochloride
WO2005092886A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of tiagabine
WO2006013550A2 (en) * 2004-08-04 2006-02-09 Ranbaxy Laboratories Limited Process for preparation of piperidine carboxylic acid
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US20080051435A1 (en) * 2006-08-18 2008-02-28 Cephalon, Inc. Crystalline and amorphous forms of tiagabine
US20080064727A1 (en) * 2006-08-18 2008-03-13 Cephalon, Inc. Crystalline forms of tiagabine hydrochloride
CN101857591B (zh) * 2009-04-09 2013-06-05 北京京卫燕康药物研究所有限公司 盐酸噻加宾晶型及其制备方法
CN103554093B (zh) * 2013-11-12 2015-10-21 四川科瑞德凯华制药有限公司 噻加宾乙酯盐酸盐及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof

Also Published As

Publication number Publication date
FI110096B (fi) 2002-11-29
EP0579681A1 (en) 1994-01-26
DK58291D0 (da) 1991-04-02
AU661483B2 (en) 1995-07-27
AU1641592A (en) 1992-11-02
JPH06506209A (ja) 1994-07-14
WO1992017473A1 (en) 1992-10-15
FI934298L (fi) 1993-09-30
CA2107223A1 (en) 1992-10-03
NO933524L (no) 1993-10-01
GR3030919T3 (en) 1999-11-30
ATE180781T1 (de) 1999-06-15
ZA922297B (en) 1992-12-30
EP0579681B1 (en) 1999-06-02
NZ242191A (en) 1994-07-26
NO933524D0 (no) 1993-10-01
IL101358A0 (en) 1992-11-15
US5354760A (en) 1994-10-11
IL101358A (en) 1996-08-04
DE69229339D1 (de) 1999-07-08
ES2134801T3 (es) 1999-10-16
DE69229339T2 (de) 1999-12-30
DK0579681T3 (da) 1999-11-15
CA2107223C (en) 2005-02-15
NO304113B1 (no) 1998-10-26

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Legal Events

Date Code Title Description
MA Patent expired