FI932680A - Fusionspolypeptider - Google Patents

Fusionspolypeptider Download PDF

Info

Publication number: FI932680A
Authority: FI; Finland
Prior art keywords: fusionspolypeptider
Prior art date: 1990-12-13

Application number

FI932680A

Other languages

English (en)

Other versions

FI932680A0 (fi

Inventor

Teresa M Kubiak

Satish K Sharma

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-12-13

Filing date

1993-06-11

Publication date

1993-06-11

1993-06-11 Application filed by Upjohn Co filed Critical Upjohn Co

1993-06-11 Publication of FI932680A publication Critical patent/FI932680A/fi

1993-06-11 Publication of FI932680A0 publication Critical patent/FI932680A0/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Vascular Medicine (AREA)
Peptides Or Proteins (AREA)

FI932680A 1990-12-13 1993-06-11 Fusionspolypeptider FI932680A0 (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US62672790A	1990-12-13	1990-12-13

Publications (2)

Publication Number	Publication Date
FI932680A true FI932680A (fi)	1993-06-11
FI932680A0 FI932680A0 (fi)	1993-06-11

Family

ID=24511577

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI932680A FI932680A0 (fi)	1990-12-13	1993-06-11	Fusionspolypeptider

Country Status (13)

Country	Link
EP (1)	EP0561971A1 (fi)
JP (1)	JPH06503473A (fi)
AU (1)	AU662508B2 (fi)
CA (1)	CA2094512A1 (fi)
CZ (1)	CZ109393A3 (fi)
FI (1)	FI932680A0 (fi)
HU (1)	HUT69963A (fi)
IE (1)	IE914347A1 (fi)
NO (1)	NO932148L (fi)
RU (1)	RU2114119C1 (fi)
SK (1)	SK60893A3 (fi)
TW (1)	TW213923B (fi)
WO (1)	WO1992010576A1 (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050272652A1 (en)	1999-03-29	2005-12-08	Gault Victor A	Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
JP2000350590A (ja) *	1999-04-12	2000-12-19	Pfizer Prod Inc	成長ホルモン及び成長ホルモン放出ホルモン組成物
US6759393B1 (en)	1999-04-12	2004-07-06	Pfizer Inc.	Growth hormone and growth hormone releasing hormone compositions
WO2001036643A1 (en) *	1999-11-19	2001-05-25	Transkaryotic Therapies, Inc.	Nucleic acid construct for optimized production of products
EP1205551A1 (en) *	2000-11-09	2002-05-15	Pfizer Products Inc.	Growth hormone and growth hormone releasing hormone compositions
EP1694356B1 (en)	2003-12-09	2011-02-16	Novo Nordisk A/S	Regulation of food preference using glp-1 agonists
EP1758575A1 (en)	2004-06-11	2007-03-07	Novo Nordisk A/S	Counteracting drug-induced obesity using glp-1 agonists
US8263545B2 (en)	2005-02-11	2012-09-11	Amylin Pharmaceuticals, Inc.	GIP analog and hybrid polypeptides with selectable properties
CA2597649A1 (en)	2005-02-11	2006-08-17	Amylin Pharmaceuticals, Inc.	Gip analog and hybrid polypeptides with selectable properties
US7855279B2 (en)	2005-09-27	2010-12-21	Amunix Operating, Inc.	Unstructured recombinant polymers and uses thereof
CA2644712C (en) †	2006-03-06	2016-09-13	Amunix, Inc.	Unstructured recombinant polymers and uses thereof
US8497240B2 (en)	2006-08-17	2013-07-30	Amylin Pharmaceuticals, Llc	DPP-IV resistant GIP hybrid polypeptides with selectable properties
MX2011008094A (es)	2009-02-03	2012-02-13	Amunix Operating Inc	Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos.
AU2010290131C1 (en)	2009-08-24	2015-12-03	Amunix Operating Inc.	Coagulation factor VII compositions and methods of making and using same
EP2528935B1 (en)	2010-01-29	2019-03-27	Archer-Daniels-Midland Company	Peptide domains that bind small molecules of industrial significance
LT2822577T (lt)	2012-02-15	2019-03-25	Bioverativ Therapeutics Inc.	Rekombinantiniai faktoriaus viii baltymai
CA2864904C (en)	2012-02-15	2023-04-25	Amunix Operating Inc.	Factor viii compositions and methods of making and using same
EP3033097B1 (en)	2013-08-14	2021-03-10	Bioverativ Therapeutics Inc.	Factor viii-xten fusions and uses thereof
CN108472337B (zh)	2015-08-03	2022-11-25	比奥贝拉蒂治疗公司	因子ix融合蛋白以及其制备和使用方法
JP2020500874A (ja)	2016-12-02	2020-01-16	バイオベラティブセラピューティクスインコーポレイテッド	キメラ凝固因子を使用して血友病性関節症を処置する方法
CN111051338B (zh) *	2017-06-29	2024-12-03	乌雷卡有限公司	具有改进的药物学性能的前药肽
WO2019222682A1 (en)	2018-05-18	2019-11-21	Bioverativ Therapeutics Inc.	Methods of treating hemophilia a

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4703004A (en) *	1984-01-24	1987-10-27	Immunex Corporation	Synthesis of protein with an identification peptide
US4569794A (en) *	1984-12-05	1986-02-11	Eli Lilly And Company	Process for purifying proteins and compounds useful in such process
CA1340522C (en) *	1987-03-10	1999-05-04	Heinz Dobeli	Fusion proteins containing neighbouring histidines for improved purification
ES2063360T3 (es) *	1989-06-16	1995-01-01	Upjohn Co	Analogos potentes de grf, estabilizados.
WO1991015589A1 (en) *	1990-04-09	1991-10-17	The Upjohn Company	Improved process of purifying recombinant proteins and compounds useful in such process

1991
- 1991-12-12 CA CA002094512A patent/CA2094512A1/en not_active Abandoned
- 1991-12-12 HU HU9301705A patent/HUT69963A/hu unknown
- 1991-12-12 EP EP92901817A patent/EP0561971A1/en not_active Withdrawn
- 1991-12-12 SK SK60893A patent/SK60893A3/sk unknown
- 1991-12-12 AU AU91165/91A patent/AU662508B2/en not_active Ceased
- 1991-12-12 WO PCT/US1991/009152 patent/WO1992010576A1/en not_active Application Discontinuation
- 1991-12-12 RU RU93045577A patent/RU2114119C1/ru active
- 1991-12-12 CZ CS931093A patent/CZ109393A3/cs unknown
- 1991-12-12 JP JP4501996A patent/JPH06503473A/ja active Pending
- 1991-12-13 IE IE434791A patent/IE914347A1/en not_active Application Discontinuation
- 1991-12-17 TW TW080109839A patent/TW213923B/zh active
1993
- 1993-06-11 FI FI932680A patent/FI932680A0/fi not_active Application Discontinuation
- 1993-06-11 NO NO93932148A patent/NO932148L/no unknown

Also Published As

Publication number	Publication date
RU2114119C1 (ru)	1998-06-27
HUT69963A (en)	1995-09-28
JPH06503473A (ja)	1994-04-21
IE914347A1 (en)	1992-06-17
HU9301705D0 (en)	1993-10-28
EP0561971A1 (en)	1993-09-29
NO932148L (no)	1993-08-09
CZ109393A3 (en)	1994-01-19
AU662508B2 (en)	1995-09-07
AU9116591A (en)	1992-07-08
WO1992010576A1 (en)	1992-06-25
TW213923B (fi)	1993-10-01
CA2094512A1 (en)	1992-06-14
NO932148D0 (no)	1993-06-11
SK60893A3 (en)	1993-10-06
FI932680A0 (fi)	1993-06-11

Publication	Publication Date	Title
DE69119415D1 (de)	1996-06-13	Mitralklappenersatz
FI925335A0 (fi)	1992-11-25	Pulsresponsanordning
FI933013A (fi)	1993-06-30	Frysta dessertsammansaettningar och- produkter
FI931369A0 (fi)	1993-03-26	Flytande detergentkompositioner
FI930295A (fi)	1993-01-25	Haorformningsgelkomposition
FI930878A0 (fi)	1993-02-26	A-substituerade tryptofan-dipeptoidderivat
FI932680A0 (fi)	1993-06-11	Fusionspolypeptider
FI932636A0 (fi)	1993-06-09	Monteringsunderlag foer gejdstaenger
FI924291A (fi)	1992-09-25	Foertoejningssystem
NO913940D0 (no)	1991-10-08	Masseblekeopploesning
FI932219A (fi)	1993-05-14	Injektionsspruta
FI930781A0 (fi)	1993-02-22	Gjutformanordning
FI932197A (fi)	1993-05-14	Semduramicinfoerblandning
DE69118732D1 (de)	1996-05-23	Elektrophotorezeptor
FI924303A (fi)	1992-09-25	Belaeggningskomposition
FI923972A (fi)	1992-09-04	Tryckvattenreaktors braensle
DE69133418D1 (de)	2004-10-28	Photoumwandlerschaltung
FI905816A (fi)	1992-05-27	Säiliörakenne
NO176007C (no)	1995-01-18	Kantfölgeaggregat
KR920011282U (ko)	1992-07-24	큐봉
IT226094Y1 (it)	1997-04-18	Paraturacciolo
FI932081A (fi)	1993-05-07	Gerotorpumpar
SE9002375D0 (sv)	1990-07-06	Foerdelningsanordning
BR9101437A (pt)	1991-11-26	Copoliester
FI87989B (fi)	1992-12-15	Elektrisk bastuugn

Legal Events

Date	Code	Title	Description
1996-07-16	HC	Name/ company changed in application	Owner name: PHARMACIA & UPJOHN COMPANY
1998-06-30	FD	Application lapsed