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FI931707L - 1,2,4-OXADIAZOLYL-PHENOXIALKYLISOXAZOLER OCH DERAS ANVAENDNING SOM VIRUSMOTARBETANDE AEMNEN - Google Patents

1,2,4-OXADIAZOLYL-PHENOXIALKYLISOXAZOLER OCH DERAS ANVAENDNING SOM VIRUSMOTARBETANDE AEMNEN Download PDF

Info

Publication number
FI931707L
FI931707L FI931707A FI931707A FI931707L FI 931707 L FI931707 L FI 931707L FI 931707 A FI931707 A FI 931707A FI 931707 A FI931707 A FI 931707A FI 931707 L FI931707 L FI 931707L
Authority
FI
Finland
Prior art keywords
virusmotarbetande
phenoxialkylisoxazoler
aemnen
oxadiazolyl
och deras
Prior art date
Application number
FI931707A
Other languages
Finnish (fi)
Other versions
FI931707A0 (en
FI112229B (en
Inventor
Guy Dominic Diana
Theodore John Nitz
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of FI931707A0 publication Critical patent/FI931707A0/en
Publication of FI931707L publication Critical patent/FI931707L/en
Application granted granted Critical
Publication of FI112229B publication Critical patent/FI112229B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI931707A 1992-04-15 1993-04-15 Process for the preparation of novel therapeutically useful 1,2,4-oxadiazolylphenoxyalkylisoxazoles FI112229B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86928792 1992-04-15
US07/869,287 US5349068A (en) 1992-04-15 1992-04-15 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Publications (3)

Publication Number Publication Date
FI931707A0 FI931707A0 (en) 1993-04-15
FI931707L true FI931707L (en) 1993-10-16
FI112229B FI112229B (en) 2003-11-14

Family

ID=25353269

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931707A FI112229B (en) 1992-04-15 1993-04-15 Process for the preparation of novel therapeutically useful 1,2,4-oxadiazolylphenoxyalkylisoxazoles

Country Status (26)

Country Link
US (3) US5349068A (en)
EP (1) EP0566199B1 (en)
JP (1) JP3103845B2 (en)
KR (1) KR100314158B1 (en)
AT (1) ATE189958T1 (en)
AU (1) AU666528B2 (en)
CA (1) CA2094012C (en)
CZ (1) CZ285845B6 (en)
DE (1) DE69327913T2 (en)
DK (1) DK0566199T3 (en)
ES (1) ES2143487T3 (en)
FI (1) FI112229B (en)
GR (1) GR3033486T3 (en)
HU (2) HU220606B1 (en)
IL (1) IL105372A (en)
MX (1) MX9302169A (en)
MY (1) MY110191A (en)
NO (1) NO302700B1 (en)
NZ (1) NZ247411A (en)
PH (1) PH30454A (en)
PT (1) PT566199E (en)
RU (1) RU2114112C1 (en)
SG (1) SG50663A1 (en)
SK (1) SK279786B6 (en)
TW (1) TW239140B (en)
UA (1) UA35557C2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
US6528652B1 (en) 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
CA2449544A1 (en) * 2001-06-08 2002-12-19 Cytovia, Inc. Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs
US7129359B2 (en) 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
CA2459376A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
CA2459375A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
EP2193792B1 (en) 2001-12-07 2011-08-31 Ana Maria Sandino Neomycin for increasing the survival of aquatic animals exposed to IPNV
AU2003215246A1 (en) * 2002-02-14 2003-09-04 Viropharma Incorporated Methods of reducing rhinovirus contagion and related compositions
JP2006516250A (en) * 2002-12-18 2006-06-29 サイトビア インコーポレイティッド 3,5-disubstituted- [1,2,4] -oxadiazoles and their derivatives and their use as caspase activators and apoptosis inducers
US7259174B2 (en) * 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds
US20060030550A1 (en) * 2004-08-04 2006-02-09 Lithgow Theodore L Pharmaceutical formulations
JP2009526063A (en) * 2006-02-09 2009-07-16 シェーリング コーポレイション Pharmaceutical formulation
MX2008010353A (en) * 2006-02-09 2009-03-05 Schering Corp Pharmaceutical formulations.
JP2009526064A (en) * 2006-02-09 2009-07-16 シェーリング コーポレイション Pharmaceutical formulation
ES2550152T3 (en) 2006-12-13 2015-11-04 F. Hoffmann-La Roche Ag 2- (Piperidin-4-yl) -4-phenoxy-or phenylamino-pyrimidine derivatives as non-nucleoside reverse transcriptase inhibitors
KR101031584B1 (en) * 2009-04-21 2011-04-27 파인오토시스템(주) Infrared irradiation device for vehicles with the front part opened and closed
CN103102322B (en) * 2011-11-14 2016-02-24 上海交通大学 Oxazole compounds and preparation method thereof, medical composition and its use
KR20210046649A (en) 2018-08-21 2021-04-28 교린 세이야꾸 가부시키 가이샤 Bicyclic heteroaromatic ring derivatives
CA3152534A1 (en) * 2019-09-27 2021-04-01 Collaborations Pharmaceuticals, Inc. Isoxazole-3-carboxamide derivatives and their use for treatment of diseases caused by virus infection
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents

Also Published As

Publication number Publication date
HUT65574A (en) 1994-07-28
IL105372A (en) 1998-12-27
NO302700B1 (en) 1998-04-14
JPH0649066A (en) 1994-02-22
CZ285845B6 (en) 1999-11-17
AU3688193A (en) 1993-10-21
DK0566199T3 (en) 2000-06-19
AU666528B2 (en) 1996-02-15
UA35557C2 (en) 2001-04-16
CA2094012A1 (en) 1993-10-16
HU9301084D0 (en) 1993-06-28
PT566199E (en) 2000-09-29
PH30454A (en) 1997-05-28
KR930021637A (en) 1993-11-22
ATE189958T1 (en) 2000-03-15
CZ59793A3 (en) 1994-02-16
HU220606B1 (en) 2002-03-28
FI931707A0 (en) 1993-04-15
EP0566199A1 (en) 1993-10-20
MY110191A (en) 1998-02-28
IL105372A0 (en) 1993-08-18
DE69327913T2 (en) 2000-10-12
ES2143487T3 (en) 2000-05-16
CA2094012C (en) 2001-08-21
GR3033486T3 (en) 2000-09-29
SK35393A3 (en) 1994-06-08
NZ247411A (en) 1994-06-27
JP3103845B2 (en) 2000-10-30
TW239140B (en) 1995-01-21
US5643929A (en) 1997-07-01
HU211320A9 (en) 1995-11-28
NO931366D0 (en) 1993-04-14
NO931366L (en) 1993-10-18
KR100314158B1 (en) 2002-02-19
SK279786B6 (en) 1999-03-12
US5349068A (en) 1994-09-20
EP0566199B1 (en) 2000-03-01
SG50663A1 (en) 1998-07-20
RU2114112C1 (en) 1998-06-27
US5464848A (en) 1995-11-07
FI112229B (en) 2003-11-14
DE69327913D1 (en) 2000-04-06
MX9302169A (en) 1993-10-01

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Owner name: SANOFI

PC Transfer of assignment of patent

Owner name: SANOFI

MA Patent expired