FI931682A - Tackykininreceptorantagonister, isokinoloner och deras framstaellning - Google Patents
Tackykininreceptorantagonister, isokinoloner och deras framstaellning Download PDFInfo
- Publication number
- FI931682A FI931682A FI931682A FI931682A FI931682A FI 931682 A FI931682 A FI 931682A FI 931682 A FI931682 A FI 931682A FI 931682 A FI931682 A FI 931682A FI 931682 A FI931682 A FI 931682A
- Authority
- FI
- Finland
- Prior art keywords
- tackykininreceptorantagonister
- isokinoloner
- deras framstaellning
- och deras
- och
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9529192 | 1992-04-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI931682A0 FI931682A0 (fi) | 1993-04-14 |
| FI931682A true FI931682A (fi) | 1993-10-16 |
Family
ID=14133676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI931682A FI931682A (fi) | 1992-04-15 | 1993-04-14 | Tackykininreceptorantagonister, isokinoloner och deras framstaellning |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5523305A (fi) |
| EP (1) | EP0566069A1 (fi) |
| KR (1) | KR930021202A (fi) |
| CN (1) | CN1083054A (fi) |
| AU (1) | AU657045B2 (fi) |
| CA (1) | CA2094117A1 (fi) |
| FI (1) | FI931682A (fi) |
| HU (1) | HUT70148A (fi) |
| NO (1) | NO179550C (fi) |
| NZ (1) | NZ247302A (fi) |
| TW (1) | TW241258B (fi) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0634402A1 (en) * | 1993-07-14 | 1995-01-18 | Takeda Chemical Industries, Ltd. | Isochinolinone derivatives, their production and use |
| TW263498B (fi) * | 1993-11-10 | 1995-11-21 | Takeda Pharm Industry Co Ltd | |
| US5770590A (en) * | 1995-03-24 | 1998-06-23 | Takeda Chemical Industries, Ltd. | Cyclic compounds, their prudiction and use |
| TW394773B (en) * | 1995-03-24 | 2000-06-21 | Takeda Chemical Industries Ltd | Cyclic compounds for antagonizing tachykinin receptor, substance p receptor and neurokinin a receptor, their production and pharmaceutical composition |
| CA2476162A1 (en) * | 2002-02-13 | 2003-08-21 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| JP4824563B2 (ja) | 2003-09-23 | 2011-11-30 | メルク・シャープ・エンド・ドーム・コーポレイション | イソキノリンカリウムチャネル阻害剤 |
| US7781457B2 (en) | 2003-09-23 | 2010-08-24 | Merck Sharp & Dohme Corp. | Isoquinolinone potassium channel inhibitors |
| ES2672099T3 (es) | 2011-07-04 | 2018-06-12 | Irbm - Science Park S.P.A. | Antagonistas del receptor NK-1 para el tratamiento de la neovascularización corneal |
| RU2020131446A (ru) | 2018-02-26 | 2022-03-28 | Оспедале Сан Раффаэле С.Р.Л. | Антагонисты nk-1 для применения в лечении глазной боли |
| WO2021180885A1 (en) | 2020-03-11 | 2021-09-16 | Ospedale San Raffaele S.R.L. | Treatment of stem cell deficiency |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2647902A (en) * | 1951-02-16 | 1953-08-04 | Smith Kline French Lab | Method for the preparation of tetrahydroisoquinolone derivatives |
| US2809969A (en) * | 1955-11-07 | 1957-10-15 | Bristol Lab Inc | Isoquinolone derivatives |
| US3247212A (en) * | 1963-03-19 | 1966-04-19 | Dow Chemical Co | Thio substituted 3 amino isoquinolines |
| US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
| DE2030675A1 (en) * | 1969-06-23 | 1971-02-11 | Arthur D Little, Inc , Cambridge, Mass (V St A) | 3-amino-4-phenyl-isoquinoline derivs |
| IL45823A (en) * | 1973-10-20 | 1977-10-31 | Hoechst Ag | Substituted 1-phenyl-4-alkyl(dialkyl or cyclic) aminoalkyl-1,4-dihydro-2h-isoquinoline-3-one derivatives |
| TW205037B (fi) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
| JPH03181465A (ja) * | 1989-12-11 | 1991-08-07 | Takeda Chem Ind Ltd | キノリン誘導体 |
| US5143919A (en) * | 1990-08-17 | 1992-09-01 | Takeda Chemical Industries, Ltd. | Thienopyridine derivatives and their pharmaceutical use |
| JPH059179A (ja) * | 1990-09-27 | 1993-01-19 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及びａｃａｔ阻害剤 |
| DE69110828T2 (de) * | 1990-10-16 | 1995-11-30 | Takeda Chemical Industries Ltd | Heterozyklische Aminderivate, deren Herstellung und deren Verwendung. |
-
1993
- 1993-03-30 TW TW082102343A patent/TW241258B/zh active
- 1993-03-31 NZ NZ247302A patent/NZ247302A/en unknown
- 1993-04-01 AU AU35663/93A patent/AU657045B2/en not_active Ceased
- 1993-04-13 US US08/045,219 patent/US5523305A/en not_active Expired - Fee Related
- 1993-04-14 HU HU9301080A patent/HUT70148A/hu unknown
- 1993-04-14 EP EP93106015A patent/EP0566069A1/en not_active Withdrawn
- 1993-04-14 NO NO931364A patent/NO179550C/no unknown
- 1993-04-14 FI FI931682A patent/FI931682A/fi not_active Application Discontinuation
- 1993-04-14 KR KR1019930006221A patent/KR930021202A/ko not_active IP Right Cessation
- 1993-04-15 CA CA002094117A patent/CA2094117A1/en not_active Abandoned
- 1993-04-15 CN CN93105950A patent/CN1083054A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUT70148A (en) | 1995-09-28 |
| NO931364L (no) | 1993-10-18 |
| KR930021202A (ko) | 1993-11-22 |
| NO179550B (no) | 1996-07-22 |
| NZ247302A (en) | 1994-12-22 |
| HU9301080D0 (en) | 1993-06-28 |
| FI931682A0 (fi) | 1993-04-14 |
| AU3566393A (en) | 1993-10-21 |
| CA2094117A1 (en) | 1993-10-16 |
| AU657045B2 (en) | 1995-02-23 |
| CN1083054A (zh) | 1994-03-02 |
| EP0566069A1 (en) | 1993-10-20 |
| NO931364D0 (no) | 1993-04-14 |
| US5523305A (en) | 1996-06-04 |
| TW241258B (fi) | 1995-02-21 |
| NO179550C (no) | 1996-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |