FI931625L - Cromaner and thiochromaner with retinoid activity - Google Patents

Cromaner and thiochromaner with retinoid activity Download PDF

Info

Publication number: FI931625L
Authority: FI; Finland
Prior art keywords: thiochromaner; cromaner; retinoid activity; retinoid; activity
Prior art date: 1990-10-09

Application number

FI931625A

Other languages

Finnish (fi)

Other versions

FI931625A0 (en

Inventor

Roshantha A S Chandraratna

Original Assignee

Allergan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-09

Filing date

1993-04-08

Publication date

1993-06-07

1993-04-08 Application filed by Allergan Inc filed Critical Allergan Inc

1993-04-08 Publication of FI931625A0 publication Critical patent/FI931625A0/en

1993-06-07 Publication of FI931625L publication Critical patent/FI931625L/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI931625A 1990-10-09 1993-04-08 Cromaner and thiochromaner with retinoid activity FI931625L (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59488290A	1990-10-09	1990-10-09
PCT/US1991/006901 WO1992006084A1 (en)	1990-10-09	1991-09-24	Chromans and thiochromans with retinoid-like activity

Publications (2)

Publication Number	Publication Date
FI931625A0 FI931625A0 (en)	1993-04-08
FI931625L true FI931625L (en)	1993-06-07

Family

ID=24380813

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI931625A FI931625L (en)	1990-10-09	1993-04-08	Cromaner and thiochromaner with retinoid activity

Country Status (12)

Country	Link
EP (1)	EP0553156A4 (en)
JP (1)	JPH06501948A (en)
AU (1)	AU652189B2 (en)
CA (1)	CA2092178A1 (en)
FI (1)	FI931625L (en)
HU (1)	HUT63405A (en)
IE (1)	IE913569A1 (en)
IL (1)	IL99617A0 (en)
PL (1)	PL168679B1 (en)
PT (1)	PT99188A (en)
WO (1)	WO1992006084A1 (en)
ZA (1)	ZA918026B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2101160A1 (en) *	1991-02-13	1992-08-14	Roshantha A. Chandraratna	Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity
FR2691149B1 (en) *	1992-05-18	1994-07-08	Adir	NOVEL THIOCHROMANIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US5451603A (en) *	1993-03-11	1995-09-19	Zymogenetics, Inc.	3,4-diarylchromans for treatment of dermatitis
CN1255396C (en) *	1996-03-18	2006-05-10	卫材株式会社	Carboxylic acid derivatives having fused rings
US6740676B2 (en) *	2002-03-19	2004-05-25	Allergan, Inc.	4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome p450rai inhibitory activity
SG177579A1 (en)	2009-07-16	2012-02-28	Stiefel Laboratories	Tazarotene derivatives
CN107176945B (en)	2016-03-11	2021-06-08	中国科学院上海有机化学研究所	A kind of retinoic acid compound, its preparation method, intermediate and application

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4810804A (en) *	1987-03-26	1989-03-07	Allergan, Inc.	Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
US4980369A (en) *	1989-09-19	1990-12-25	Allergan, Inc.	Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity
CA2101160A1 (en) *	1991-02-13	1992-08-14	Roshantha A. Chandraratna	Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity

1991
- 1991-09-24 EP EP19910917856 patent/EP0553156A4/en not_active Withdrawn
- 1991-09-24 AU AU87210/91A patent/AU652189B2/en not_active Ceased
- 1991-09-24 HU HU931030A patent/HUT63405A/en unknown
- 1991-09-24 WO PCT/US1991/006901 patent/WO1992006084A1/en not_active Application Discontinuation
- 1991-09-24 JP JP3516762A patent/JPH06501948A/en active Pending
- 1991-09-24 CA CA002092178A patent/CA2092178A1/en not_active Abandoned
- 1991-09-24 PL PL91299061A patent/PL168679B1/en unknown
- 1991-10-01 IL IL99617A patent/IL99617A0/en unknown
- 1991-10-08 ZA ZA918026A patent/ZA918026B/en unknown
- 1991-10-09 PT PT99188A patent/PT99188A/en not_active Application Discontinuation
- 1991-10-16 IE IE356991A patent/IE913569A1/en not_active Application Discontinuation
1993
- 1993-04-08 FI FI931625A patent/FI931625L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0553156A1 (en)	1993-08-04
HU9301030D0 (en)	1993-07-28
EP0553156A4 (en)	1993-11-18
HUT63405A (en)	1993-08-30
IE913569A1 (en)	1992-04-22
ZA918026B (en)	1992-06-24
IL99617A0 (en)	1992-08-18
PL168679B1 (en)	1996-03-29
JPH06501948A (en)	1994-03-03
PT99188A (en)	1992-09-30
FI931625A0 (en)	1993-04-08
AU652189B2 (en)	1994-08-18
WO1992006084A1 (en)	1992-04-16
AU8721091A (en)	1992-04-28
CA2092178A1 (en)	1992-04-10

Publication	Publication Date	Title
BR9101311A (en)	1991-11-26	DIAPER
BR1100580A (en)	2000-06-06	Compound and complex
BR9304732A (en)	1994-06-07	Absorbent structure and absorbent article
FI870026A (en)	1987-01-05	MEDICAL PROJECTORS AND WASHERS FOERTILLSLUTNINGSOEPPNINGARNA FOERSEDD KRANVENTIL.
IT1140999B (en)	1986-10-10	MODIFIED GLYCOSAMINOGLICANS EQUIPPED WITH ANTI-LIPEMIC ACTIVITY AND WITHOUT ANTI-COAGULANT ACTIVITY
DE59108611D1 (en)	1997-04-17	Picolin oxides
FI932114A0 (en)	1993-05-10	Maolspecifika erythrocytes and thromboerytrocytes
BR9100157A (en)	1991-10-22	ABSORBENT STRUCTURE AND METHOD OF DOING THE SAME
FI931625L (en)	1993-06-07	Cromaner and thiochromaner with retinoid activity
BR9102456A (en)	1992-01-21	CHAIR
TR25296A (en)	1993-01-01	COMBINATIONS WITH FUNGUSID ACTIVITY
TR25733A (en)	1993-09-01	COMBINATIONS WITH FUNGUSID ACTIVITY
DE69119398D1 (en)	1996-06-13	Checkweighers with length consideration
FI960342A0 (en)	1996-01-25	Benzoxazinones and benzothiazinones with therapeutic activity
BR9205281A (en)	1993-07-27	IMMUNO-REGULATING AND NEURO-REGULATING PENTAPEPTIDEOS
DK256090D0 (en)	1990-10-24	chopper
NO932219D0 (en)	1993-06-16	PESTICIDING RELATIONSHIPS
DK124390D0 (en)	1990-05-18	PROSTAGLAND INERIVATIVES WITH ANTITHROMOBOTIC EFFECT
BR9002261A (en)	1991-11-12	THERMOKIT-HEATER AND MICROSECADER
FI88480C (en)	1993-05-25	gantry
SE8902995L (en)	1990-03-24	STEPS AND STEPS
KR920008992U (en)	1992-06-16	Magnetic spit
KR920000051U (en)	1992-01-27	Fish and fish catching complex
KR920010884U (en)	1992-07-24	Squid
DK179288A (en)	1988-10-02	DIOXOLAN AND DIOXANDER DERIVATIVES

Legal Events

Date	Code	Title	Description
1995-10-14	FD	Application lapsed