FI931625A - Kromaner och tiokromaner med retinoidlik aktivitet - Google Patents

Kromaner och tiokromaner med retinoidlik aktivitet Download PDF

Info

Publication number: FI931625A
Authority: FI; Finland
Prior art keywords: thiochromers; chromans; retinoid activity; retinoid; activity
Prior art date: 1990-10-09

Application number

FI931625A

Other languages

English (en)

Finnish (fi)

Other versions

FI931625A0 (fi

Inventor

Roshantha A S Chandraratna

Original Assignee

Allergan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-09

Filing date

1993-04-08

Publication date

1993-06-07

1993-04-08 Application filed by Allergan Inc filed Critical Allergan Inc

1993-04-08 Publication of FI931625A0 publication Critical patent/FI931625A0/fi

1993-06-07 Publication of FI931625A publication Critical patent/FI931625A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI931625A 1990-10-09 1993-04-08 Kromaner och tiokromaner med retinoidlik aktivitet FI931625A (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59488290A	1990-10-09	1990-10-09
PCT/US1991/006901 WO1992006084A1 (en)	1990-10-09	1991-09-24	Chromans and thiochromans with retinoid-like activity

Publications (2)

Publication Number	Publication Date
FI931625A0 FI931625A0 (fi)	1993-04-08
FI931625A true FI931625A (fi)	1993-06-07

Family

ID=24380813

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI931625A FI931625A (fi)	1990-10-09	1993-04-08	Kromaner och tiokromaner med retinoidlik aktivitet

Country Status (12)

Country	Link
EP (1)	EP0553156A4 (pt)
JP (1)	JPH06501948A (pt)
AU (1)	AU652189B2 (pt)
CA (1)	CA2092178A1 (pt)
FI (1)	FI931625A (pt)
HU (1)	HUT63405A (pt)
IE (1)	IE913569A1 (pt)
IL (1)	IL99617A0 (pt)
PL (1)	PL168679B1 (pt)
PT (1)	PT99188A (pt)
WO (1)	WO1992006084A1 (pt)
ZA (1)	ZA918026B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU648158B2 (en) *	1991-02-13	1994-04-14	Allergan, Inc.	Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity
FR2691149B1 (fr) *	1992-05-18	1994-07-08	Adir	Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5451603A (en) *	1993-03-11	1995-09-19	Zymogenetics, Inc.	3,4-diarylchromans for treatment of dermatitis
CN1255396C (zh) *	1996-03-18	2006-05-10	卫材株式会社	含有稠环的羧酸衍生物
US6740676B2 (en) *	2002-03-19	2004-05-25	Allergan, Inc.	4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome p450rai inhibitory activity
NZ598240A (en)	2009-07-16	2013-10-25	Stiefel Laboratories	Tazarotene derivatives
CN107176945B (zh)	2016-03-11	2021-06-08	中国科学院上海有机化学研究所	一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4810804A (en) *	1987-03-26	1989-03-07	Allergan, Inc.	Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
US4980369A (en) *	1989-09-19	1990-12-25	Allergan, Inc.	Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity
AU648158B2 (en) *	1991-02-13	1994-04-14	Allergan, Inc.	Chroman and thiochromans with phenylethynyl substituents at the 7-position having retinoid-like biological activity

1991
- 1991-09-24 JP JP3516762A patent/JPH06501948A/ja active Pending
- 1991-09-24 HU HU931030A patent/HUT63405A/hu unknown
- 1991-09-24 WO PCT/US1991/006901 patent/WO1992006084A1/en not_active Application Discontinuation
- 1991-09-24 PL PL91299061A patent/PL168679B1/pl unknown
- 1991-09-24 AU AU87210/91A patent/AU652189B2/en not_active Ceased
- 1991-09-24 CA CA002092178A patent/CA2092178A1/en not_active Abandoned
- 1991-09-24 EP EP19910917856 patent/EP0553156A4/en not_active Withdrawn
- 1991-10-01 IL IL99617A patent/IL99617A0/xx unknown
- 1991-10-08 ZA ZA918026A patent/ZA918026B/xx unknown
- 1991-10-09 PT PT99188A patent/PT99188A/pt not_active Application Discontinuation
- 1991-10-16 IE IE356991A patent/IE913569A1/en not_active Application Discontinuation
1993
- 1993-04-08 FI FI931625A patent/FI931625A/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
PT99188A (pt)	1992-09-30
AU8721091A (en)	1992-04-28
EP0553156A4 (en)	1993-11-18
AU652189B2 (en)	1994-08-18
CA2092178A1 (en)	1992-04-10
PL168679B1 (en)	1996-03-29
WO1992006084A1 (en)	1992-04-16
FI931625A0 (fi)	1993-04-08
ZA918026B (en)	1992-06-24
HUT63405A (en)	1993-08-30
IL99617A0 (en)	1992-08-18
JPH06501948A (ja)	1994-03-03
IE913569A1 (en)	1992-04-22
HU9301030D0 (en)	1993-07-28
EP0553156A1 (en)	1993-08-04

Publication	Publication Date	Title
BR9101311A (pt)	1991-11-26	Fralda
BR8901524A (pt)	1990-03-01	Artigo absorvente descartavel
DK104091D0 (da)	1991-05-31	Absorptionslegeme
DE59108611D1 (de)	1997-04-17	Picolinoxide
FI932114A0 (fi)	1993-05-10	Maolspecifika erytrocyter och tromboerytrocyter
BR9100157A (pt)	1991-10-22	Estrutura absorvente e metodo de fazer a mesma
FI923352A (fi)	1993-01-25	Fluorelastomera blandpolymerer modifierade med perfluoralkylvinyleter och baserade pao vinylidenfluorid
BR8902476A (pt)	1990-11-13	Estrutura absorvente e produto absorvente
FI931625A (fi)	1993-06-07	Kromaner och tiokromaner med retinoidlik aktivitet
DK89991A (da)	1991-05-14	Absorberende engangsartikel
TR25733A (tr)	1993-09-01	Fungusid aktivitesine sahip bilesik kombinasyonlari
NO914343L (no)	1992-06-05	Marin konstruksjon
NO914486L (no)	1992-05-18	Marin konstruksjon
FI960342A (fi)	1996-01-25	Bentsoksatsinonit ja bentsotiatsinonit, joilla on terapeuttista aktiivisuutta
DK124390A (da)	1990-05-18	Prostaglandinderivater med antitrombotisk virkning
SE8902995D0 (sv)	1989-09-12	Trappa och trappsteg
DK179288A (da)	1988-10-02	Dioxolan- og dioxanderivater
FI88480C (fi)	1993-05-25	Lastningsbrygga
SE8900412D0 (sv)	1989-02-07	Saett att bereda hudar och skinn
SE8800855D0 (sv)	1988-03-10	Monter- och demonteringsbart flytetyg
KR920007433U (ko)	1992-05-19	피부보호용 타이즈
BR9002261A (pt)	1991-11-12	Termokit-aquecedor e microsecadora
SE8803040D0 (sv)	1988-08-31	Nerings och jorforbettringsmedel
SE8802976D0 (sv)	1988-08-25	Dubbelsparig och enkelsparig jernveg
FI925277A (fi)	1994-05-21	Monterbar och demonterbar laettbyggd bostad

Legal Events

Date	Code	Title	Description
1995-10-14	FD	Application lapsed