FI931333A0 - Foerfarande foer framstaellning av formoterol och liknande foereningar - Google Patents

Foerfarande foer framstaellning av formoterol och liknande foereningar

Info

Publication number: FI931333A0
Authority: FI; Finland
Prior art keywords: faring; formal; directed; present; formoterol
Prior art date: 1990-09-26

Application number

FI931333A

Other languages

English (en)

Other versions

FI931333L (fi

FI111714B (fi

Inventor

Jan William Trofast

Edib Jakupovic

Lena Katarina Maonsson

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-26

Filing date

1993-03-25

Publication date

1993-03-25

1993-03-25 Application filed by Astra Ab filed Critical Astra Ab

1993-03-25 Publication of FI931333A0 publication Critical patent/FI931333A0/fi

1993-04-22 Publication of FI931333L publication Critical patent/FI931333L/fi

2003-09-15 Application granted granted Critical

2003-09-15 Publication of FI111714B publication Critical patent/FI111714B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)
Pyrrole Compounds (AREA)

FI931333A 1990-09-26 1993-03-25 Uusi menetelmä formoterolin ja lähisukuisten yhdisteiden valmistamiseksi FI111714B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE9003057A SE9003057D0 (sv)	1990-09-26	1990-09-26	New process
SE9003057		1990-09-26
PCT/SE1991/000643 WO1992005147A1 (en)	1990-09-26	1991-09-25	New process for preparing formoterol and related compounds
SE9100643		1991-09-25

Publications (3)

Publication Number	Publication Date
FI931333A0 true FI931333A0 (fi)	1993-03-25
FI931333L FI931333L (fi)	1993-04-22
FI111714B FI111714B (fi)	2003-09-15

Family

ID=20380456

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI931333A FI111714B (fi)	1990-09-26	1993-03-25	Uusi menetelmä formoterolin ja lähisukuisten yhdisteiden valmistamiseksi

Country Status (28)

Country	Link
EP (1)	EP0550612B1 (fi)
JP (1)	JP2801401B2 (fi)
KR (1)	KR0179639B1 (fi)
AT (1)	ATE134990T1 (fi)
AU (1)	AU652386B2 (fi)
BG (1)	BG61605B1 (fi)
CA (1)	CA2091343C (fi)
CZ (1)	CZ284256B6 (fi)
DE (1)	DE69117768T2 (fi)
DK (1)	DK0550612T3 (fi)
EE (1)	EE02979B1 (fi)
ES (1)	ES2084831T3 (fi)
FI (1)	FI111714B (fi)
GR (1)	GR3020134T3 (fi)
HK (1)	HK52297A (fi)
HU (1)	HU214054B (fi)
IE (1)	IE74387B1 (fi)
IS (1)	IS1684B (fi)
LT (1)	LT3813B (fi)
LV (1)	LV10770B (fi)
NO (1)	NO301709B1 (fi)
PL (1)	PL166434B1 (fi)
PT (1)	PT99051B (fi)
RU (1)	RU2079486C1 (fi)
SE (1)	SE9003057D0 (fi)
SG (1)	SG43150A1 (fi)
SK (1)	SK22793A3 (fi)
WO (1)	WO1992005147A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6299863B1 (en)	1992-04-03	2001-10-09	Sepracor Inc.	Aerosol formulations containing micronized optically pure (R,R) formoterol for bronchodilating therapy
US6866839B2 (en)	1991-04-05	2005-03-15	Sepracor Inc.	Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
US5795564A (en) *	1991-04-05	1998-08-18	Sepracor, Inc.	Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
US5629200A (en) *	1993-11-18	1997-05-13	Daicel Chemical Industries, Ltd.	Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
SE9404080L (sv) *	1993-12-28	1995-06-29	Ciba Geigy Ag	Förfarande för framställning av en optiskt ren enantiomer av formoterol
US6040344A (en)	1996-11-11	2000-03-21	Sepracor Inc.	Formoterol process
PT938467E (pt) *	1996-11-11	2002-11-29	Sepracor Inc	Processo para a preparacao de isomeros opticamente puros de formoterol
US6303145B2 (en)	1999-05-10	2001-10-16	Sepracor Inc.	(S,R) formoterol methods and compositions
AR028948A1 (es)	2000-06-20	2003-05-28	Astrazeneca Ab	Compuestos novedosos
DE10290562D2 (de) *	2001-02-22	2004-04-29	Universitaetsklinikum Charite	Zielkomplex als Mittel zur Hemmung von Tumorzellen und zur Stimulierung der Angiogenese
US6472563B1 (en)	2001-11-09	2002-10-29	Sepracor Inc.	Formoterol tartrate process and polymorph
TWI359675B (en)	2003-07-10	2012-03-11	Dey L P	Bronchodilating β-agonist compositions
TW200738634A (en)	2005-08-02	2007-10-16	Astrazeneca Ab	New salt
WO2008035380A2 (en) *	2006-09-19	2008-03-27	Natco Pharma Limited	An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts
TW200825084A (en)	2006-11-14	2008-06-16	Astrazeneca Ab	New compounds 521
EP2205966A2 (en) *	2007-10-29	2010-07-14	Generics Ýuk¨Limited	Novel chromatography methods
CN102089304A (zh)	2008-05-13	2011-06-08	阿斯利康(瑞典)有限公司	作为m3毒蕈碱性受体拮抗剂的奎宁环衍生物
CN101921200B (zh) *	2009-06-16	2014-01-15	上海医药工业研究院	一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法
WO2011061527A1 (en)	2009-11-17	2011-05-26	Astrazeneca Ab	Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
CN115368250B (zh) *	2022-09-02	2024-07-26	博诺康源(北京)药业科技有限公司	拆分福莫特罗手性中间体的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2305092A1 (de)	1972-02-05	1973-08-16	Yamanouchi Pharma Co Ltd	Alpha-aminomethylbenzylalkoholderivate
GB1468156A (en) *	1973-07-19	1977-03-23	Ici Ltd	Phenylethylamine derivatives
ES2005492A6 (es)	1987-12-23	1989-03-01	Lasa Lab	Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i).

1990
- 1990-09-26 SE SE9003057A patent/SE9003057D0/xx unknown
1991
- 1991-09-25 SG SG1996004479A patent/SG43150A1/en unknown
- 1991-09-25 PT PT99051A patent/PT99051B/pt not_active IP Right Cessation
- 1991-09-25 PL PL91298237A patent/PL166434B1/pl unknown
- 1991-09-25 JP JP3516242A patent/JP2801401B2/ja not_active Expired - Lifetime
- 1991-09-25 EP EP91917624A patent/EP0550612B1/en not_active Expired - Lifetime
- 1991-09-25 SK SK22793A patent/SK22793A3/sk unknown
- 1991-09-25 WO PCT/SE1991/000643 patent/WO1992005147A1/en active IP Right Grant
- 1991-09-25 RU RU9193005269A patent/RU2079486C1/ru active
- 1991-09-25 AT AT91917624T patent/ATE134990T1/de not_active IP Right Cessation
- 1991-09-25 IS IS3756A patent/IS1684B/is unknown
- 1991-09-25 CA CA002091343A patent/CA2091343C/en not_active Expired - Lifetime
- 1991-09-25 DE DE69117768T patent/DE69117768T2/de not_active Expired - Lifetime
- 1991-09-25 ES ES91917624T patent/ES2084831T3/es not_active Expired - Lifetime
- 1991-09-25 HU HU9300867A patent/HU214054B/hu unknown
- 1991-09-25 DK DK91917624.8T patent/DK0550612T3/da active
- 1991-09-25 CZ CZ93442A patent/CZ284256B6/cs not_active IP Right Cessation
- 1991-09-25 KR KR1019930700901A patent/KR0179639B1/ko not_active Expired - Lifetime
- 1991-09-25 AU AU86520/91A patent/AU652386B2/en not_active Expired
- 1991-09-26 IE IE337391A patent/IE74387B1/en not_active IP Right Cessation
1993
- 1993-03-23 NO NO931058A patent/NO301709B1/no not_active IP Right Cessation
- 1993-03-24 BG BG97576A patent/BG61605B1/bg unknown
- 1993-03-25 FI FI931333A patent/FI111714B/fi not_active IP Right Cessation
- 1993-08-10 LV LVP-93-1025A patent/LV10770B/en unknown
- 1993-12-30 LT LTIP1715A patent/LT3813B/lt not_active IP Right Cessation
1994
- 1994-11-23 EE EE9400425A patent/EE02979B1/xx unknown
1996
- 1996-05-31 GR GR960401514T patent/GR3020134T3/el unknown
1997
- 1997-04-24 HK HK52297A patent/HK52297A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2084831T3 (es)	1996-05-16
PL166434B1 (pl)	1995-05-31
AU652386B2 (en)	1994-08-25
HUT65912A (en)	1994-07-28
RU2079486C1 (ru)	1997-05-20
JP2801401B2 (ja)	1998-09-21
NO931058D0 (no)	1993-03-23
IE913373A1 (en)	1992-04-08
HU214054B (en)	1997-12-29
EP0550612B1 (en)	1996-03-06
PT99051B (pt)	1999-02-26
AU8652091A (en)	1992-04-15
CA2091343C (en)	2002-07-09
SE9003057D0 (sv)	1990-09-26
JPH06501262A (ja)	1994-02-10
BG61605B1 (bg)	1998-01-30
NO301709B1 (no)	1997-12-01
FI931333L (fi)	1993-04-22
SG43150A1 (en)	1997-10-17
KR0179639B1 (ko)	1999-05-15
CZ284256B6 (cs)	1998-10-14
NO931058L (no)	1993-03-23
LTIP1715A (en)	1995-07-25
CA2091343A1 (en)	1992-03-27
SK22793A3 (en)	1993-07-07
HU9300867D0 (en)	1993-06-28
DK0550612T3 (da)	1996-07-22
LV10770A (lv)	1995-08-20
WO1992005147A1 (en)	1992-04-02
DE69117768D1 (de)	1996-04-11
EP0550612A1 (en)	1993-07-14
BG97576A (bg)	1994-03-31
CZ44293A3 (en)	1994-01-19
PT99051A (pt)	1992-08-31
IE74387B1 (en)	1997-07-30
ATE134990T1 (de)	1996-03-15
LT3813B (en)	1996-03-25
IS1684B (is)	1998-02-24
HK52297A (en)	1997-05-02
DE69117768T2 (de)	1996-08-29
IS3756A7 (is)	1992-03-27
EE02979B1 (et)	1997-04-15
FI111714B (fi)	2003-09-15
LV10770B (en)	1996-04-20
GR3020134T3 (en)	1996-08-31

Publication	Publication Date	Title
FI931333A0 (fi)	1993-03-25	Foerfarande foer framstaellning av formoterol och liknande foereningar
FI925342L (fi)	1992-11-25	Menetelmä terapeuttisesti aktiivisen (+)- -(2,3-dimetoksifenyyli)-1-/2-(4-fluorifenyyli)etyyli/-4-piperidiinimetanolin valmistamiseksi
FI104170B1 (fi)	1999-11-30	Menetelmä terapeuttisesti käyttökelpoisten 3-amidopyratsolijohdannaisten valmistamiseksi
FI914905L (fi)	1992-04-19	Menetelmä uusien terapeuttisesti käyttökelpoisten merkaptoasetyyliamidopyrrolo- ja -pyridobentsatsepiinijohdannaisten valmistamiseksi
NO910395D0 (no)	1991-02-01	Analogifremgangsmaate for fremstilling av terapeutisk virksomme 4-isoxazolcarboxamidderivater.
RU93005269A (ru)	1996-04-27	Способ получения формотерола и родственных соединений
FI98455B (fi)	1997-03-14	Menetelmä terapeuttisesti aktiivisten indolijohdannaisten valmistamiseksi
NO914250L (no)	1992-05-04	Fremgangsmaate for fremstilling av piperazinderivater
NO912797D0 (no)	1991-07-17	Analogifremgangsmaate for fremstilling av terapeutisk virksomme karbostirilderivater.
NO924028L (no)	1992-10-16	Forbedret fremgangsmaate for fremstilling av substituerte indolonderivater
FI931033A (fi)	1993-09-11	Foerfarande foer framstaellning av dialkyl-2,3-pyridindikarboxylat och derivat daerav ur a,b-omaettade oximer och aminobutendioat
NO914053L (no)	1992-04-21	Fremgangsmaate for fremstilling av 8-klorokinolonderivater
NO912979D0 (no)	1991-07-31	Fremgangsmaate for fremstilling av 2-(9-fluorenoyl)-carbapenederivater.
NO912980D0 (no)	1991-07-31	Fremgangsmaate for fremstilling av 2-(9-fluorenoyl)-carbapenderivater
NO914985D0 (no)	1991-12-17	Fremgangsmaate for fremstilling av 15-nitro-tabersonin-derivater
ES2114891T3 (es)	1998-06-16	Nuevas formulaciones farmaceuticas de 5-(2-cloro-1-hidroxietil)-4-metiltiazol.
FI912733L (fi)	1991-12-08	Menetelmä terapeuttisesti käyttökelpoisten /(1-aryylipyrrolidin-2-yyli)metyyli/piperatsiinijohdannaisten valmistamiseksi
NO179909C (no)	1997-01-08	Analogifremgangsmåte for fremstilling av terapeutisk avtive 6-substituerte purinylpiperazinderivater
NO914452D0 (no)	1991-11-13	Fremgangsmaate for fremstilling av isokinolinderivater
ES2032573T3 (es)	1993-02-16	Procedimiento de preparacion de derivados de 4,4-dimetil-tetrahidropir-2-ona.
FI901953A (fi)	1991-10-20	Foerfarande och anordning foer rengoering av roekgaser.

Legal Events

Date	Code	Title	Description
2011-11-25	MA	Patent expired