FI930264A - 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel - Google Patents

4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel Download PDF

Info

Publication number: FI930264A
Authority: FI; Finland
Prior art keywords: formula; nitrogen; group; compounds; optionally substituted
Prior art date: 1992-01-23

Application number

FI930264A

Other languages

English (en)

Other versions

FI930264A0 (fi

Inventor

Ernest S Hamanaka

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-23

Filing date

1993-01-22

Publication date

1993-07-24

1993-01-22 Application filed by Pfizer filed Critical Pfizer

1993-01-22 Publication of FI930264A0 publication Critical patent/FI930264A0/fi

1993-07-24 Publication of FI930264A publication Critical patent/FI930264A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Quinoline Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)

FI930264A 1992-01-23 1993-01-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel FI930264A (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US82463992A	1992-01-23	1992-01-23

Publications (2)

Publication Number	Publication Date
FI930264A0 FI930264A0 (fi)	1993-01-22
FI930264A true FI930264A (fi)	1993-07-24

Family

ID=25241935

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FI930264A FI930264A (fi)	1992-01-23	1993-01-22	4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel
FI20010074A FI20010074A (fi)	1992-01-23	2001-01-12	Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
FI20010074A FI20010074A (fi)	1992-01-23	2001-01-12	Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia

Country Status (16)

Country	Link
EP (1)	EP0623112B1 (fi)
JP (1)	JP2668163B2 (fi)
KR (1)	KR950700284A (fi)
AT (1)	ATE175196T1 (fi)
AU (1)	AU3323393A (fi)
CA (1)	CA2128093C (fi)
DE (1)	DE69228069T2 (fi)
DK (1)	DK0623112T3 (fi)
ES (1)	ES2125325T3 (fi)
FI (2)	FI930264A (fi)
HU (1)	HUT63625A (fi)
IL (1)	IL104420A0 (fi)
MX (1)	MX9300361A (fi)
NO (1)	NO942757L (fi)
WO (1)	WO1993015058A1 (fi)
ZA (1)	ZA93482B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6133326A (en)	1994-08-31	2000-10-17	Pfizer Inc	Compositions and methods for decreasing sebum production
CA2321237A1 (en)	1998-02-25	1999-09-02	Masami Muraoka	Pyridone derivatives and process for producing the same
US6452008B2 (en)	1998-02-25	2002-09-17	Sumitomo Pharmaceuticals Company, Limited	Pyridone derivatives and process for preparing the same
AP2002002612A0 (en)	2000-02-02	2002-09-30	Warner Lambert Co	Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders
US8309562B2 (en)	2003-07-03	2012-11-13	Myrexis, Inc.	Compounds and therapeutical use thereof
CA2572442A1 (fr) *	2004-07-30	2006-03-09	Palumed S.A.	Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
FR2874922A1 (fr) *	2004-07-30	2006-03-10	Palumed Sa	Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
CA2592900A1 (en)	2005-01-03	2006-07-13	Myriad Genetics Inc.	Nitrogen containing bicyclic compounds and therapeutical use thereof
US8258145B2 (en)	2005-01-03	2012-09-04	Myrexis, Inc.	Method of treating brain cancer
US11618751B1 (en)	2022-03-25	2023-04-04	Ventus Therapeutics U.S., Inc.	Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE892088L (en) *	1988-07-12	1990-01-12	William Henry Deryk Morris	Quinoline derivatives, their production and use
WO1991004027A1 (en) *	1989-09-15	1991-04-04	Pfizer Inc.	New n-aryl and n-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat)
TW205037B (fi) *	1989-10-06	1993-05-01	Takeda Pharm Industry Co Ltd
CA2075632C (en) *	1990-02-10	2001-10-16	Kanji Meguro	Chromene derivatives, their production and use
DE9290049U1 (de) *	1991-04-26	1994-01-05	Pfizer Inc., New York, N.Y.	4-Aryl-3-(heteroarylureido)chinolin-Derivate

1992
- 1992-12-21 AU AU33233/93A patent/AU3323393A/en not_active Abandoned
- 1992-12-21 DE DE69228069T patent/DE69228069T2/de not_active Expired - Fee Related
- 1992-12-21 JP JP5513207A patent/JP2668163B2/ja not_active Expired - Fee Related
- 1992-12-21 CA CA002128093A patent/CA2128093C/en not_active Expired - Fee Related
- 1992-12-21 EP EP93901257A patent/EP0623112B1/en not_active Expired - Lifetime
- 1992-12-21 AT AT93901257T patent/ATE175196T1/de not_active IP Right Cessation
- 1992-12-21 DK DK93901257T patent/DK0623112T3/da active
- 1992-12-21 WO PCT/US1992/010886 patent/WO1993015058A1/en active IP Right Grant
- 1992-12-21 ES ES93901257T patent/ES2125325T3/es not_active Expired - Lifetime
1993
- 1993-01-18 IL IL104420A patent/IL104420A0/xx unknown
- 1993-01-22 MX MX9300361A patent/MX9300361A/es unknown
- 1993-01-22 ZA ZA93482A patent/ZA93482B/xx unknown
- 1993-01-22 FI FI930264A patent/FI930264A/fi unknown
- 1993-01-22 HU HU9300197A patent/HUT63625A/hu unknown
1994
- 1994-07-22 NO NO942757A patent/NO942757L/no unknown
- 1994-07-22 KR KR1019940702519A patent/KR950700284A/ko not_active Application Discontinuation
2001
- 2001-01-12 FI FI20010074A patent/FI20010074A/fi unknown

Also Published As

Publication number	Publication date
JPH07503712A (ja)	1995-04-20
AU3323393A (en)	1993-09-01
IL104420A0 (en)	1993-05-13
EP0623112A1 (en)	1994-11-09
DE69228069D1 (de)	1999-02-11
MX9300361A (es)	1994-06-30
FI20010074A (fi)	2001-01-12
KR950700284A (ko)	1995-01-16
ES2125325T3 (es)	1999-03-01
NO942757D0 (no)	1994-07-22
WO1993015058A1 (en)	1993-08-05
CA2128093A1 (en)	1993-08-05
CA2128093C (en)	1998-02-03
ATE175196T1 (de)	1999-01-15
ZA93482B (en)	1994-07-22
DE69228069T2 (de)	1999-05-20
EP0623112B1 (en)	1998-12-30
HUT63625A (en)	1993-09-28
JP2668163B2 (ja)	1997-10-27
FI930264A0 (fi)	1993-01-22
NO942757L (no)	1994-07-22
HU9300197D0 (en)	1993-04-28
DK0623112T3 (da)	1999-08-30

Publication	Publication Date	Title
DK1026147T3 (da)	2004-03-22	Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
FI943561A0 (fi)	1994-07-29	Uudet ainekoostumukset
NO20013379L (no)	2001-07-06	4-okso-1,4-dihydro-3-kinolinkarboksamider som antivirusmidler
ES2105098T3 (es)	1997-10-16	Derivados de 4-benzoil-isoxazol y su uso como herbicidas.
DK254587A (da)	1987-11-21	Positionsspecifikke alkyleringsmidler
DK0918776T3 (da)	2004-07-12	Totalsyntese af antitumor acylfulvener
FI930264A (fi)	1993-07-24	4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel
DE69428142D1 (de)	2001-10-11	Quinolin- oder Quinazolinderivate, deren Herstellung und Verwendung
DE69314929D1 (de)	1997-12-04	Benzolderivate
ES2077697T3 (es)	1995-12-01	Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
TW349935B (en)	1999-01-11	Oxime ether compounds, their intermediates and their use as pesticides
YU90192A (sh)	1995-12-04	LANOSTA-7,9-DIEN-3β, 32-DIOL I POSTUPAK ZA NJEGOVO DOBIJANJE,9-DIEN-3BETA, 32-DIOL I POSTUPAK ZA NJEGOVU SINTEZU
ATE99306T1 (de)	1994-01-15	Antagonisten von leukotrien d4.